Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Christian, Wadsack"'
Autor:
Désirée Forstner, Jacqueline Guettler, Beatrice A. Brugger, Freya Lyssy, Lena Neuper, Christine Daxboeck, Gerhard Cvirn, Julia Fuchs, Kristin Kraeker, Alina Frolova, Daniela S. Valdes, Christina Stern, Birgit Hirschmugl, Herbert Fluhr, Christian Wadsack, Berthold Huppertz, Olivia Nonn, Florian Herse, Martin Gauster
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Tissue insults in response to inflammation, hypoxia and ischemia are accompanied by the release of ATP into the extracellular space. There, ATP modulates several pathological processes, including chemotaxis, inflammasome induction and platelet activa
Externí odkaz:
https://doaj.org/article/a66dbffd2a5348b3ace6efb87477d991
Autor:
Natascha Berger, Tom van der Wel, Birgit Hirschmugl, Thomas Baernthaler, Juergen Gindlhuber, Nermeen Fawzy, Thomas Eichmann, Ruth Birner-Gruenberger, Robert Zimmermann, Mario van der Stelt, Christian Wadsack
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionLipids and fatty acids are key components in metabolic processes of the human placenta, thereby contributing to the development of the fetus. Placental dyslipidemia and aberrant activity of lipases have been linked to diverse pregnancy as
Externí odkaz:
https://doaj.org/article/554df234a0eb4e46ba913fb591099917
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Hofbauer cells (HBCs) are resident macrophages of the human placenta, regulating immune tolerance and tissue homeostasis. HBCs of a normal placenta (CTR) exhibit mainly an anti-inflammatory M2 phenotype. Under exaggerated chronic inflammation during
Externí odkaz:
https://doaj.org/article/0fa763a8e83e4ca09c7ab8557fef1445
Autor:
Meekha George, Magdalena Lang, Chaitanya Chakravarthi Gali, Joshua Adekunle Babalola, Carmen Tam-Amersdorfer, Anika Stracke, Herbert Strobl, Robert Zimmermann, Ute Panzenboeck, Christian Wadsack
Publikováno v:
Cells, Vol 12, Iss 8, p 1186 (2023)
Oxysterols are oxidized cholesterol derivatives whose systemic levels are found elevated in pregnancy disorders such as gestational diabetes mellitus (GDM). Oxysterols act through various cellular receptors and serve as a key metabolic signal, coordi
Externí odkaz:
https://doaj.org/article/a5f735ac4f3546cc84246a90c443a31f
Publikováno v:
Antioxidants, Vol 12, Iss 4, p 795 (2023)
Preeclampsia (PE) is linked to an overall increased cardiovascular risk for both the mother and child. Functional impairment of high-density lipoproteins (HDL) may contribute to the excess cardiovascular risk associated with PE. In this study, we inv
Externí odkaz:
https://doaj.org/article/88816416203a4ad4b52975286284b2d7
Autor:
Michael M. Gruber, Birgit Hirschmugl, Natascha Berger, Magdalena Holter, Snježana Radulović, Gerd Leitinger, Laura Liesinger, Andrea Berghold, Eva Roblegg, Ruth Birner-Gruenberger, Vesna Bjelic-Radisic, Christian Wadsack
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background Nanoparticles, which are exposed to biological fluids are rapidly interacting with proteins and other biomolecules forming a corona. In addition to dimension, charge and material the distinct protein corona influences the interpla
Externí odkaz:
https://doaj.org/article/e8d861398ea7426d81263d366b590ad2
Autor:
Julia T. Stadler, Mireille N. M. van Poppel, Christian Wadsack, Michael Holzer, Anja Pammer, David Simmons, David Hill, Gernot Desoye, Gunther Marsche, DALI Core Investigator Group
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 199 (2023)
Pregravid obesity is one of the major risk factors for pregnancy complications such as gestational diabetes mellitus (GDM) and an increased risk of cardiovascular events in children of affected mothers. However, the biological mechanisms that underpi
Externí odkaz:
https://doaj.org/article/dc8bc87061ee4335b8bfa7d701bba95b
Autor:
Julia T. Stadler, M. N. M. van Poppel, Christina Christoffersen, David Hill, Christian Wadsack, David Simmons, Gernot Desoye, Gunther Marsche, DALI Core Investigator Group
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 68 (2022)
Gestational hypertension (GHTN) is associated with an increased cardiovascular risk for mothers and their offspring later in life. High-density lipoproteins (HDL) are anti-atherogenic by promoting efflux of cholesterol from macrophages and suppressio
Externí odkaz:
https://doaj.org/article/eae7cd87a4db4fe99943d1b33fc9faac
Autor:
Lenka Tupova, Birgit Hirschmugl, Simona Sucha, Veronika Pilarova, Virág Székely, Éva Bakos, Lucie Novakova, Csilla Özvegy-Laczka, Christian Wadsack, Martina Ceckova
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 129, Iss , Pp 110506- (2020)
Special attention is required when pharmacological treatment is indicated for a pregnant woman. P-glycoprotein (MDR1) is a well-known transporter localized in the maternal blood-facing apical membrane of placental syncytiotrophoblast and is considere
Externí odkaz:
https://doaj.org/article/d4e484f433464d4d84578391241d9a20
Autor:
Susana Contreras-Duarte, Nicolás Santander, Ruth Birner-Gruenberger, Christian Wadsack, Attilio Rigotti, Dolores Busso
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-5 (2018)
Abstract Scavenger receptor class B type 1 (SR-B1) plays an essential role in high density lipoprotein (HDL) metabolism. SR-B1 deficient (SR-B1 KO) mice are prone to atherosclerosis and exhibit abnormally large, cholesterol-rich, dysfunctional HDL. I
Externí odkaz:
https://doaj.org/article/3b58e5572496421e8e8aeff5902c7fa6