Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Christian, Steinhäuser"'
Autor:
Paula Baum, Anna Beinhauer, Lara Zirwes, Linda Loenneker, Ronald Jabs, Rajeevan T. Narayanan, Marcel Oberlaender, Gerald Seifert, Helmut Kettenmann, Christian Steinhäuser
Publikováno v:
iScience, Vol 27, Iss 10, Pp 111043- (2024)
Summary: Astrocytes and oligodendrocytes in the ventrobasal thalamus are electrically coupled through gap junctions. We have previously shown that these cells form large panglial networks, which have a key role in the transfer of energy substrates to
Externí odkaz:
https://doaj.org/article/c812d3324e424deea19c757ab5b7a461
Autor:
Nine Kompier, Marcus Semtner, Sophie Walter, Natali Kakabadze, Christian Steinhäuser, Christiane Nolte, Helmut Kettenmann
Publikováno v:
Current Research in Neurobiology, Vol 7, Iss , Pp 100137- (2024)
We established a longitudinal acute slice preparation of transgenic mouse optic nerve to characterize membrane properties and coupling of glial cells by patch-clamp and dye-filling, complemented by immunohistochemistry. Unlike in cortex or hippocampu
Externí odkaz:
https://doaj.org/article/442aab50b1714340a191a36b1ddd9ebb
Autor:
Antonio Cibelli, Randy Stout, Aline Timmermann, Laura de Menezes, Peng Guo, Karen Maass, Gerald Seifert, Christian Steinhäuser, David C. Spray, Eliana Scemes
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The neurovascular unit (NVU) consists of cells intrinsic to the vessel wall, the endothelial cells and pericytes, and astrocyte endfeet that surround the vessel but are separated from it by basement membrane. Endothelial cells are primarily
Externí odkaz:
https://doaj.org/article/ad79486a15d049f9b8d3ca38056578a7
Autor:
Marijke De Bock, Maarten De Smet, Stijn Verwaerde, Hanane Tahiri, Steffi Schumacher, Valérie Van Haver, Katja Witschas, Christian Steinhäuser, Nathalie Rouach, Roosmarijn E. Vandenbroucke, Luc Leybaert
Publikováno v:
JCI Insight, Vol 7, Iss 16 (2022)
The blood-brain barrier is formed by capillary endothelial cells expressing connexin 37 (Cx37), Cx40, and Cx43 and is joined by closely apposed astrocytes expressing Cx43 and Cx30. We investigated whether connexin-targeting peptides could limit barri
Externí odkaz:
https://doaj.org/article/066b30bb320c47808fa69a498209687e
Autor:
Peter Bedner, Christian Steinhäuser
Publikováno v:
Cells, Vol 12, Iss 12, p 1669 (2023)
The gap-junction-coupled astroglial network plays a central role in the regulation of neuronal activity and synchronisation, but its involvement in the pathogenesis of neuronal diseases is not yet understood. Here, we present the current state of kno
Externí odkaz:
https://doaj.org/article/2893151a1b7a483c90aecf5c25208966
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/4ccaf5454e6c4b98b34d8c0f8a3f3e80
Autor:
Amira A. H. Ali, Anna Stahr, Marc Ingenwerth, Martin Theis, Christian Steinhäuser, Charlotte von Gall
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-12 (2019)
Abstract Background The astroglial connexins Cx30 and Cx43 contribute to many important CNS functions including cognitive behaviour, motoric capacity and regulation of the sleep-wake cycle. The sleep wake cycle, is controlled by the circadian system.
Externí odkaz:
https://doaj.org/article/20b89121e6754f589c53ff3338d929ce
Autor:
Stefan Hardt, Dario Tascio, Stefan Passlick, Aline Timmermann, Ronald Jabs, Christian Steinhäuser, Gerald Seifert
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Synaptic and axonal glutamatergic signaling to NG2 glia in white matter is critical for the cells’ differentiation and activity dependent myelination. However, in gray matter the impact of neuron-to-NG2 glia signaling is still elusive, because most
Externí odkaz:
https://doaj.org/article/f5ed9c22b65242efab86a5cf20ba8f2b
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Blood–brain barrier (BBB) dysfunction following brain insults has been associated with the development and progression of focal epilepsy, although the underlying molecular mechanisms are not fully elucidated yet. Activation of transforming growth f
Externí odkaz:
https://doaj.org/article/a3bcdd17b7ce4d19902ebd00e5beb561
Autor:
Julia Müller, Aline Timmermann, Lukas Henning, Hendrik Müller, Christian Steinhäuser, Peter Bedner
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
An imbalance of excitation and inhibition has been associated with the pathophysiology of epilepsy. Loss of GABAergic interneurons and/or synaptic inhibition has been shown in various epilepsy models and in human epilepsy. Despite this loss, several
Externí odkaz:
https://doaj.org/article/147e6ad988c0446dab8a0e8c24dded0e