Výsledky vyhledávání - "Christian, Singer"

Akademický článek

Clinical characterization, prognostic, and predictive values of HER2-low in patients with early breast cancer in the PALLAS trial (ABCSG-42/AFT-05/BIG-14–13/PrE0109)

Publikováno v: Breast Cancer Research, Vol 26, Iss 1, Pp 1-10 (2024)

Abstract Background Bidirectional crosstalk between HER2 and estrogen receptor (ER) pathways may influence outcomes and the efficacy of endocrine therapy (ET). Low HER2 expression levels (HER2-low) have emerged as a predictive biomarker in patients w

Externí odkaz: https://doaj.org/article/c4f4965043a847fba7a786c64cdbe554

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Akademický článek

Impact of Electronic Patient-Reported Outcomes on Unplanned Consultations and Hospitalizations in Patients With Cancer Undergoing Systemic Therapy: Results of a Patient-Reported Outcome Study Compared With Matched Retrospective Data

Autor: Andreas Trojan, Christian Kühne, Michael Kiessling, Johannes Schumacher, Stefan Dröse, Christian Singer, Christian Jackisch, Christoph Thomssen, Gerd A Kullak-Ublick

Publikováno v: JMIR Formative Research, Vol 8, p e55917 (2024)

BackgroundThe evaluation of electronic patient-reported outcomes (ePROs) is increasingly being used in clinical studies of patients with cancer and enables structured and standardized data collection in patients’ everyday lives. So far, few studies

Externí odkaz: https://doaj.org/article/869aa6dfcdec43b9ab44d038d3dac136

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Akademický článek

Late onset toxicities associated with the use of CDK 4/6 inhibitors in hormone receptor positive (HR+), human epidermal growth factor receptor-2 negative (HER2-) metastatic breast cancer patients: a multidisciplinary, pan-EU position paper regarding their optimal management. The GIOCONDA project

Autor: Marina Elena Cazzaniga, Antonio Ciaccio, Romano Danesi, Francois P. Duhoux, Corrado Girmenia, Kalhil Zaman, Henrik Lindman, Fabrizio Luppi, Dimitrios Mavroudis, Ida Paris, Ayodele Olubukola, Ahmed Samreen, Christian Schem, Christian Singer, Anton Snegovoy

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

The personalization of therapies in breast cancer has favoured the introduction of new molecular-targeted therapies into clinical practice. Among them, cyclin-dependent kinases 4 and 6 (CDK4/6) inhibitors have acquired increasing importance, with the

Externí odkaz: https://doaj.org/article/b92d0fe6abaa453fb0590fe813591377

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Akademický článek

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Akademický článek

Liver function indicators in patients with breast cancer before and after detection of hepatic metastases-a retrospective study.

Autor: Carmen Leser, Georg Dorffner, Maximilian Marhold, Anemone Rutter, Mert Döger, Christian Singer, Deirdre Maria König-Castillo, Christine Deutschmann, Iris Holzer, Daniel König-Castillo, Daphne Gschwantler-Kaulich

Publikováno v: PLoS ONE, Vol 18, Iss 3, p e0278454 (2023)

BackgroundLiver metastases are common in patients with breast cancer, and determining the factors associated with such metastases may improve both their early detection and treatment. Given that liver function protein level changes in these patients

Externí odkaz: https://doaj.org/article/9c0e5b8ae4b04754b1c79b7e716a61dd

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Akademický článek

Chemotherapy-associated oral microbiome changes in breast cancer patients

Autor: Ingeborg Klymiuk, Ceren Bilgilier, Alexander Mahnert, Andreas Prokesch, Christoph Heininger, Ingeborg Brandl, Hanka Sahbegovic, Christian Singer, Thorsten Fuereder, Christoph Steininger

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

Cytotoxic chemotherapy with or without a combination of humanized monoclonal antibodies is regarded as the gold standard of personalized medicine for the treatment of breast cancer patients. Significant medication-related side effects are common acco

Externí odkaz: https://doaj.org/article/239be78d48c54942bbe40904be480778

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Akademický článek

CDK4/6 inhibition in low burden and extensive metastatic breast cancer: summary of an ESMO Open—Cancer Horizons pro and con discussion

Autor: Christoph Zielinski, Ahmad Awada, Joseph Gligorov, Guy Jerusalem, Christian Singer

Publikováno v: ESMO Open, Vol 4, Iss 6 (2019)

In December 2017, ESMO Open—Cancer Horizons convened a round-table discussion on the background and latest data regarding cyclin-dependent kinase (CDK)4/6 inhibitors with endocrine therapy (ET) in the treatment of endocrine-sensitive breast cancer

Externí odkaz: https://doaj.org/article/121850df68c94877b7e6b3e388ac4381

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Altered Expression of RB and pRB in Tissue Arrays of Primary Breast Cancers and Matched Axillary Lymph Node Metastases

Autor: Carmen Leser, Angelika Reiner, Georg Dorffner, Marie-Theres Kastner, Martin Igaz, Christian Singer, Deirdre Maria König-Castillo, Christine Deutschmann, Daniel König, Iris Holzer, Daphne Gschwantler-Kaulich

Publikováno v: The Breast Journal. 2022:1-6

Objectives. The retinoblastoma (RB) pathway is crucial in the development and progression of many cancers. To better understand the biology of progressive breast cancer (BC), we examined protein expression of the RB pathway in primary BCs and matched

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df390e74400b742847e5a53fa8c2cf23
https://doi.org/10.1155/2022/5221257

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