Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Christian, Leuner"'
Autor:
Haftom Temesgen Abebe, Christian Leuner, Hagazi Tesfay, Samuel Berhane, Abraha Hailu, Gabriele Wehr, Tesfay Gebregziabher, Yonas Berhane, Mulugeta Naizgi, Temesgen Tsega, Hagos Kahsay, Marta Yemane Hadush
Publikováno v:
SSRN Electronic Journal.
Background: Rheumatic heart disease (RHD) remains the leading cardiovascular disease in Ethiopian children and adults. Early treatment of bacterial sore throat is important in primary prevention of acute rheumatic fever (ARF). In Ethiopian population
Autor:
Jana Mysicka, Kevin John Smith, Gerhard Josef Heun, Udo Hahn, Gill Mundin, Mathias Krämer, Christian Leuner
Publikováno v:
Expert Opinion on Drug Metabolism & Toxicology. 8:1495-1503
To formally establish the relationship between oxycodone dissolution, in vitro, from a prolonged-release, oral, combination of oxycodone and naloxone (OXN PR) tablets with in vivo absorption, by developing a validated Level A in vitro/in vivo correla
Autor:
Thorsten Lawrenz, Markus Bartelsmeier, Marc Schloesser, Bianca Borchert, Jens Reinhardt, Claudia Strunk-Mueller, Frank Lieder, Horst Kuhn, Christian Leuner, Dorothee Meyer Zu Vilsendorf, Christoph Stellbrink, Gerald Beer
Publikováno v:
Journal of the American College of Cardiology. 57(5):572-576
Objectives The purpose of this study was to examine the efficacy and safety of endocardial radiofrequency ablation of septal hypertrophy (ERASH) for left ventricular outflow tract (LVOT) gradient reduction in hypertrophic obstructive cardiomyopathy (
Autor:
Claudia Strunk-Mueller, Dorothee Meyer Zu Vilsendorf, Thorsten Lawrenz, Christian Leuner, Frank Lieder, Christoph Stellbrink, Markus Bartelsmeier, Jens Reinhardt, Horst Kuhn, Bianca Borchert, Andre Feuchtl
Publikováno v:
Journal of the American College of Cardiology. 49:2356-2363
Objectives This study analyzed changes in intracardiac conduction during transcoronary ablation of septal hypertrophy (TASH) to identify predictors for pacemaker dependency after TASH. Background Transcoronary ablation of septal hypertrophy is an acc
Autor:
H. Kuhn, Thorsten Lawrenz, Ludger Obergassel, F. Gietzen, Frank Lieder, Christian Leuner, Christoph Stellbrink
Publikováno v:
Clinical Research in Cardiology. 95:254-260
Relatively few reports on the clinical impact of atrial fibrillation (AF) in hypertrophic obstructive cardiomyopathy (HOCM) are available. The aims of our study are to report the effect of transcoronary ablation of septal hypertrophy (TASH) on clinic
Autor:
THORSTEN LAWRENZ, LUDGER OBERGASSEL, FRANK LIEDER, CHRISTIAN LEUNER, CLAUDIA STRUNK‐MUELLER, DOROTHEE MEYER, ZU VILSENDORF, GERALD BEER, HORST KUHN
Publikováno v:
Pacing and Clinical Electrophysiology. 28:295-300
Introduction: Transcoronary ablation of septal hypertrophy (TASH) is safe and effectively reduces the intraventricular gradient in patients with hypertrophic obstructive cardiomyopathy (HOCM). To analyze the potential of anti- and proarrhythmic effec
Publikováno v:
Heart. 90:638-644
To evaluate symptomatic and haemodynamic results of transcoronary ablation of septal hypertrophy for hypertrophic obstructive cardiomyopathy in elderly patients.Tertiary referral centre for patients with hypertrophic obstructive cardiomyopathy.Retros
Autor:
Nikoletta Fotaki, Christos Reppas, Eleftheria Nicolaides, Maria Vertzoni, Erika Stippler, Christian Leuner, Edmund Kostewicz, Jennifer B. Dressman
Publikováno v:
Journal of Pharmacy and Pharmacology. 56:453-462
The objective of this study was to test various aspects of dissolution media simulating the intralumenal composition of the small intestine, including the suitability of the osmolality-adjusting agents and of the buffers, the substitution of crude so
Autor:
Hugo Berghmans, Marcus E. Brewster, Mireille Thimon, Jennifer B. Dressman, Geert Verreck, K. Six, Laurent Meublat, Kristof Van Werde, Guy Van den Mooter, Christian Leuner, Luc Benoist, Jef Peeters, Jules Mullens
Publikováno v:
Pharmaceutical Research. 20:1047-1054
Purpose. This study was done to elucidate the physical and pharmaceutical properties of itraconazole-HPMC dispersions and the influence of water on the phase separation. Methods. Extrudates were prepared using a corotating twin-screw hot-stage extrud
Autor:
Jennifer B. Dressman, Christian Leuner
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 50:47-60
The solubility behaviour of drugs remains one of the most challenging aspects in formulation development. With the advent of combinatorial chemistry and high throughput screening, the number of poorly water soluble compounds has dramatically increase