Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Christian, Krapp"'
Autor:
David Bajor, Nashat Gabrail, Alain Algazi, Diwakar Davar, Douglas Laux, Morteza Aghmesheh, Joan Morris, Vinod Ganju, Vibeke Miller Breinholt, Mette Kriegbaum, Alexander I Spira, Christian Krapp, Telma Lança, Stina Singel, Thomas Tuxen Poulsen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/69f075075b164ef298aa8033a3763d55
Autor:
Aida S. Hansen, Lea S. Jensen, Kristine R. Gammelgaard, Kristoffer G. Ryttersgaard, Christian Krapp, Jesper Just, Kasper L. Jønsson, Pia B. Jensen, Thomas Boesen, Mogens Johannsen, Anders Etzerodt, Bent W. Deleuran, Martin R. Jakobsen
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 8, Pp n/a-n/a (2023)
Abstract A key phenomenon in cancer is the establishment of a highly immunosuppressive tumour microenvironment (TME). Despite advances in immunotherapy, where the purpose is to induce tumour recognition and hence hereof tumour eradication, the majori
Externí odkaz:
https://doaj.org/article/243433d9b85349ca81ff3bd193a23e6f
Autor:
Gloria Griffante, Weronika Hewelt-Belka, Camilla Albano, Francesca Gugliesi, Selina Pasquero, Sergio Fernando Castillo Pacheco, Greta Bajetto, Paolo Ettore Porporato, Erica Mina, Marta Vallino, Christian Krapp, Martin Roelsgaard Jakobsen, John Purdy, Jens von Einem, Santo Landolfo, Valentina Dell’Oste, Matteo Biolatti
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Cellular lipid metabolism plays a pivotal role in human cytomegalovirus (HCMV) infection, as increased lipogenesis in HCMV-infected cells favors the envelopment of newly synthesized viral particles. As all cells are equipped with restriction
Externí odkaz:
https://doaj.org/article/b40fe9f446da4f5a9789a39792830e92
Autor:
David Olagnier, Aske M. Brandtoft, Camilla Gunderstofte, Nikolaj L. Villadsen, Christian Krapp, Anne L. Thielke, Anders Laustsen, Suraj Peri, Anne Louise Hansen, Lene Bonefeld, Jacob Thyrsted, Victor Bruun, Marie B. Iversen, Lin Lin, Virginia M. Artegoitia, Chenhe Su, Long Yang, Rongtuan Lin, Siddharth Balachandran, Yonglun Luo, Mette Nyegaard, Bernadette Marrero, Raphaela Goldbach-Mansky, Mona Motwani, Dylan G. Ryan, Katherine A. Fitzgerald, Luke A. O’Neill, Anne K. Hollensen, Christian K. Damgaard, Frank v. de Paoli, Hanne C. Bertram, Martin R. Jakobsen, Thomas B. Poulsen, Christian K. Holm
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Understanding how regulators of inflammation affect nucleic acid sensing is important for targeting research against inflammatory diseases and conditions. Here, the authors identify Nrf2 as an important negative regulator of STING and suggest a link
Externí odkaz:
https://doaj.org/article/5fc54bf6fbd8427c94401b47231854b6
Autor:
Gloria, Griffante, Weronika, Hewelt-Belka, Albano, Camilla, Gugliesi, Francesca, Pasquero, Selina, Sergio Fernando Castillo Pacheco, Bajetto, Greta, Porporato, Paolo Ettore, Mina, Erica, Vallino, Marta, Christian, Krapp, Martin Roelsgaard Jakobsen, John, Purdy, Jens von Einem, Landolfo, Santo Giuseppe, Dell'Oste, Valentina, Biolatti, Matteo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______970::27645003bc703055356805f0e6f75b14
http://hdl.handle.net/2318/1854454
http://hdl.handle.net/2318/1854454
Autor:
Aida S. Hansen, Lea S. Jensen, Kristoffer G. Ryttersgaard, Christian Krapp, Jesper Just, Kasper L. Joensson, Anders Etzerodt, Bent W. Deleuran, Martin R. Jakobsen
Publikováno v:
Cancer Immunology Research. 10:B12-B12
Despite recent years advancement reported for cancer immunotherapies within multiple cancer types, we still see a large group of patients failing to respond to treatment. Activation of the innate immune pathway controlled by STimulator of INterferon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ffdf40e9cf2f2a1d2b63bd1276790f1
https://doi.org/10.1158/2326-6074.tumimm22-b12
https://doi.org/10.1158/2326-6074.tumimm22-b12
Autor:
Matteo Ferrari, Christian Krapp, Michela Muscolini, Angela Santoni, Martin R. Jakobsen, Alessandra Zevini, Alessandra Zingoni, David Olagnier, John Hiscott, Enrico Palermo, Giovanna Peruzzi, Luciano Castiello, Elisabetta Vulpis
Publikováno v:
Castiello, L, Zevini, A, Vulpis, E, Muscolini, M, Ferrari, M, Palermo, E, Peruzzi, G, Krapp, C, Jakobsen, M, Olagnier, D, Zingoni, A, Santoni, A & Hiscott, J 2019, ' An optimized retinoic acid-inducible gene I agonist M8 induces immunogenic cell death markers in human cancer cells and dendritic cell activation ', Cancer Immunology, Immunotherapy, vol. 68, no. 9, pp. 1479-1492 . https://doi.org/10.1007/s00262-019-02380-2
RIG-I is a cytosolic RNA sensor that recognizes short 5 ' triphosphate RNA, commonly generated during virus infection. Upon activation, RIG-I initiates antiviral immunity, and in some circumstances, induces cell death. Because of this dual capacity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a021b4cf5bcdbe0488874886620a2142
https://doi.org/10.1007/s00262-019-02380-2
https://doi.org/10.1007/s00262-019-02380-2
Autor:
Martin R. Jakobsen, Martin K. Thomsen, Lars Østergaard, Rikke Olesen, Katharina Mack, Christian Krapp, Jesper F Højen, Martin Tolstrup, Frederik Dagnæs-Hansen, Paul W. Denton, Anna H. F. Andersen, Kasper L Jønsson
Publikováno v:
Andersen, A H F, Olesen, R, Jønsson, K L, Højen, J F, Krapp, C, Mack, K, Thomsen, M K, Østergaard, L, Tolstrup, M, Dagnæs-Hansen, F, Jakobsen, M R & Denton, P W 2019, ' cAIMP administration in humanized mice induces a chimerization-level-dependent STING response ', Immunology, vol. 157, no. 2, pp. 163-172 . https://doi.org/10.1111/imm.13061
Andersen, A H F, Olesen, R, Jønsson, K L, Højen, J F, Krapp, C, Mack, K, Thomsen, M K, Østergaard, L, Tolstrup, M, Dagnaes-Hansen, F, Jacobsen, M R & Denton, P W 2019, ' cAIMP administration in humanized mice induces a chimerization-level-dependent STING response ' Immunology . https://doi.org/10.1111/imm.13061
Immunology
Andersen, A H F, Olesen, R, Jønsson, K L, Højen, J F, Krapp, C, Mack, K, Thomsen, M K, Østergaard, L, Tolstrup, M, Dagnaes-Hansen, F, Jacobsen, M R & Denton, P W 2019, ' cAIMP administration in humanized mice induces a chimerization-level-dependent STING response ' Immunology . https://doi.org/10.1111/imm.13061
Immunology
It is well conceived that the STING signalling pathway is critical for generating a robust innate immune response to pathogens. Human and mouse STING signaling pathways are not identical, however. For example, mice lack IFI16 which has been proven im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1f8f27964c177fba22bbf3f7aa9c1e
https://doi.org/10.1111/imm.13061
https://doi.org/10.1111/imm.13061
Autor:
Biolatti, Matteo, Griffante, Gloria, Albano, Camilla, Gugliesi, Francesca, Pasquero, Selina, CASTILLO PACHECO, SERGIO FERNANDO, Porporato, Paolo Ettore, Mina, Erica, Weronika, Hewelt-Belka, Marta, Vallino, Christian, Krapp, Martin, Jakobsen, John, Purdy, Landolfo, Santo Giuseppe, Dell'Oste, Valentina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______970::3ba60aae3af3d7c83e8acc203637a941
http://hdl.handle.net/2318/1799682
http://hdl.handle.net/2318/1799682
Autor:
Matt Porteus, Niels Uldbjerg, Nadia R. Roan, L Kjær, Satish K. Pillai, Anders Laustsen, J H Egedahl, Paul W. Denton, Christian Krapp, Hai Q Tang, Martin R. Jakobsen, Rasmus O. Bak, Charlotte Christie Petersen, Mette Nyegaard
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Laustsen, A, Bak, R, Krapp, C, Kjær, L, Egedahl, J H, Petersen, C C, Pillai, S, Tang, H Q, Uldbjerg, N, Porteus, M, Roan, N R, Nyegaard, M, Denton, P W & Jakobsen, M R 2018, ' Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and function ', Nature Communications, vol. 9, no. 1, 3525 . https://doi.org/10.1038/s41467-018-05816-y
Nature Communications
Laustsen, A, Bak, R, Krapp, C, Kjær, L, Egedahl, J H, Petersen, C C, Pillai, S, Tang, H Q, Uldbjerg, N, Porteus, M, Roan, N R, Nyegaard, M, Denton, P W & Jakobsen, M R 2018, ' Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and function ', Nature Communications, vol. 9, no. 1, 3525 . https://doi.org/10.1038/s41467-018-05816-y
Plasmacytoid dendritic cells (pDC) are essential for immune competence. Here we show that pDC precursor differentiated from human CD34+ hematopoietic stem and progenitor cells (HSPC) has low surface expression of pDC markers, and has limited inductio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380e30600f8b9cde2bcb29ca6e932fec
http://link.springer.com/article/10.1038/s41467-018-05816-y
http://link.springer.com/article/10.1038/s41467-018-05816-y