Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christian, Korherr"'
Autor:
Ulrich Brinkmann, Johan Dixelius, Ira Pastan, Kerstin Koenig-Hoffmann, Christian Korherr, Hendrik Gille, Rolf Schäfer, Kristi A. Egland
Publikováno v:
Proceedings of the National Academy of Sciences. 103:4240-4245
A genome-wide phenotype screen was used to identify factors and pathways that induce proliferation of human umbilical vein endothelial cells (HUVEC). HUVEC proliferation is a recognized marker for factors that modulate vascularization. Screening “h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba98fbec61f18e6470a96bede8aca3a7
https://doi.org/10.1073/pnas.0511319103
https://doi.org/10.1073/pnas.0511319103
Autor:
Ulrich Brinkmann, Christoph Hergersberg, Rolf Schäfer, Matthias Klein, Kerstin Koenig-Hoffmann, Sascha Röhrig, Beate Gawin, Angelika L. Bonin-Debs, Irene Boche, Michael Kazinski, Andrea Gnirke, Frank Madeo, Dieter Link, Christian Korherr
Publikováno v:
International Journal of Cancer. 113:434-439
We have used a combination of high throughput functional genomics, computerized database mining and expression analyses to discover novel human tumor suppressor genes (TSGs). A genome-wide high throughput cDNA phenotype screen was established to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02de7fe3692800420e5ed315bbbff2e8
https://doi.org/10.1002/ijc.20601
https://doi.org/10.1002/ijc.20601
Autor:
Robert Hofmeister, Jürgen Radons, Werner Falk, Stefan Gabler, Christian Korherr, Holger Wesche
Publikováno v:
Journal of Biological Chemistry. 277:16456-16463
Interleukin (IL)-1 plays an important role in inflammation and regulation of immune responses. The activated IL-1 receptor complex, which consists of the IL-1 receptor type I and the IL-1 receptor accessory protein (IL-1RAcP), generates multiple cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f6afb01feaafc2ed57d04d898026c1
https://doi.org/10.1074/jbc.m201000200
https://doi.org/10.1074/jbc.m201000200
Autor:
Holger Wesche, Christian Korherr, Klaus Resch, Michael Kracht, Michael U. Martin, Werner Falk
Publikováno v:
Journal of Biological Chemistry. 272:7727-7731
Interleukin-1 (IL-1) is a central mediator of the immune system involved in acute and chronic inflammatory responses. Although the sequences of two types of IL-1 receptors are known, the exact molecular events resulting in signal transduction and cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62e01dc7fdd0e9a01db08ac1ba67cec
https://doi.org/10.1074/jbc.272.12.7727
https://doi.org/10.1074/jbc.272.12.7727
Publikováno v:
European Journal of Immunology. 27:262-267
Interleukin-1 (IL-1) is a central molecule in inflammation and immune responses whose pleiotropic activities are mediated by the type I IL-1 receptor (IL-1RI). The IL-1RI alone on the cell surface is silent after binding of the ligand. We show that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef71182056f400627f51d91012f0de4
https://doi.org/10.1002/eji.1830270139
https://doi.org/10.1002/eji.1830270139
Publikováno v:
Canadian Journal of Microbiology. 41:192-199
A 68-kDa extracellular glycoprotein from Physarum polycephalum that hydrolyses specifically poly(β-L-malic acid) by removing monomers of L-malic acid in an exolytic manner has been purified and characterized. The enzyme was purified 1740-fold from t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::745b71d43ed5cdb37e97721a763558f6
https://doi.org/10.1139/m95-187
https://doi.org/10.1139/m95-187
Autor:
Kerstin, Koenig-Hoffmann, Angelika L, Bonin-Debs, Irene, Boche, Beate, Gawin, Andrea, Gnirke, Christoph, Hergersberg, Frank, Madeo, Michael, Kazinski, Matthias, Klein, Christian, Korherr, Dieter, Link, Sascha, Röhrig, Rolf, Schäfer, Ulrich, Brinkmann
Publikováno v:
International journal of cancer. 113(3)
We have used a combination of high throughput functional genomics, computerized database mining and expression analyses to discover novel human tumor suppressor genes (TSGs). A genome-wide high throughput cDNA phenotype screen was established to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f64188b9d9f8ea9df062503d12a003a
https://pubmed.ncbi.nlm.nih.gov/15455385
https://pubmed.ncbi.nlm.nih.gov/15455385
Publikováno v:
Oncogene. 20(2)
Here, we report the identification and characterization of a new member of the RalGDS-family, which is widely expressed and interacts strongly and selectively with the GTP-bound forms of M-Ras and p21 Ras. This Ras pathway modulator (RPM), also terme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ab6245ab54767ae3e93473f7e553fa
https://pubmed.ncbi.nlm.nih.gov/11313946
https://pubmed.ncbi.nlm.nih.gov/11313946
Publikováno v:
Frontiers in Bioscience. :7243
Tank-Binding-Kinase 1 (TBK-1) has been proposed as a putative mediator in tumor angiogenesis. It was the aim of our study to gain insight into TBK-1s role in tumor angiogenesis and tumor-associated microvascular inflammation. TBK-1 overexpressing KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3329053cec8b33e993ebaf76262083b8
https://doi.org/10.2741/3225
https://doi.org/10.2741/3225
Publikováno v:
Experimental Hematology. 28:54
M-Ras is a novel member of the Ras superfamily which is oncogenic and activated by many of the same exchange factors as the classical p21 Ras proteins. However, M-Ras does not bind strongly to classical p21 Ras effectors such as Raf-1, Ral-GDS or PI3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a83c7f817a4f3e2209e19aa0a20978cf
https://doi.org/10.1016/s0301-472x(00)00258-7
https://doi.org/10.1016/s0301-472x(00)00258-7