Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Christian, Hertig"'
Publikováno v:
Plants, Vol 12, Iss 8, p 1594 (2023)
Endosperm development in barley starts with the formation of a multinucleate syncytium, followed by cellularization in the ventral part of the syncytium generating endosperm transfer cells (ETCs) as first differentiating subdomain, whereas aleurone (
Externí odkaz:
https://doaj.org/article/481d5c17735e4d599132fb77d3ce8ed1
Autor:
Sophia V. Gerasimova, Christian Hertig, Anna M. Korotkova, Ekaterina V. Kolosovskaya, Ingrid Otto, Stefan Hiekel, Alex V. Kochetov, Elena K. Khlestkina, Jochen Kumlehn
Publikováno v:
BMC Plant Biology, Vol 20, Iss S1, Pp 1-12 (2020)
Abstract Background The naked caryopsis character in barley is a domestication-associated trait defined by loss-of-function of the NUD gene. The functional NUD gene encodes an Apetala 2/Ethylene-Response Factor (AP2/ERF) controlling the formation of
Externí odkaz:
https://doaj.org/article/53fcb4d81c5b4b0c881c5f28f942083f
Autor:
Ralf Gutzmer, Caroline Robert, Gabriella Liszkay, Grant McArthur, Jacek Mackiewicz, Rodrigo Munhoz, Paolo Ascierto, Judit Olah, Paola Queirolo, Luis De La Cruz Marino, Kalpit Shah, Harper Forbes, Christian Hertig, Yibing Yan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/f0de46026009415e8098531206f1d714
Autor:
Paolo A Ascierto, Daniil Stroyakovskiy, Helen Gogas, Caroline Robert, Karl Lewis, Svetlana Protsenko, Rodrigo P Pereira, Thomas Eigentler, Piotr Rutkowski, Lev Demidov, Natalia Zhukova, Jacob Schachter, Yibing Yan, Ivor Caro, Christian Hertig, Cloris Xue, Lieke Kusters, Grant A McArthur, Ralf Gutzmer
Publikováno v:
The Lancet Oncology. 24:33-44
Autor:
Stephen Couban, Giulia Benevolo, William Donnellan, Jennifer Cultrera, Steffen Koschmieder, Srdan Verstovsek, Gregory Hooper, Christian Hertig, Maneesh Tandon, Natalie Dimier, Vikram Malhi, Francesco Passamonti
Publikováno v:
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-4 (2018)
Abstract Background The JAK inhibitor (JAKi) ruxolitinib is standard treatment for myelofibrosis (MF), but some patients are unresponsive. Pre-clinical and clinical data suggest that addition of a Hedgehog pathway inhibitor (HPI) to ruxolitinib might
Externí odkaz:
https://doaj.org/article/f3b5023c148b4fdd86ea6f5993a73a76
Autor:
Krzysztof Michalski, Christian Hertig, Dariusz R. Mańkowski, Jochen Kumlehn, Janusz Zimny, Anna M. Linkiewicz
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7038 (2021)
Cas endonuclease-mediated genome editing provides a long-awaited molecular biological approach to the modification of predefined genomic target sequences in living organisms. Although cas9/guide (g)RNA constructs are straightforward to assemble and c
Externí odkaz:
https://doaj.org/article/5fa8b0a4796345afb616ed024bb6fd58
Autor:
Paolo A, Ascierto, Daniil, Stroyakovskiy, Helen, Gogas, Caroline, Robert, Karl, Lewis, Svetlana, Protsenko, Rodrigo P, Pereira, Thomas, Eigentler, Piotr, Rutkowski, Lev, Demidov, Natalia, Zhukova, Jacob, Schachter, Yibing, Yan, Ivor, Caro, Christian, Hertig, Cloris, Xue, Lieke, Kusters, Grant A, McArthur, Ralf, Gutzmer
Publikováno v:
The Lancet. Oncology.
Primary analysis of the phase 3 IMspire150 study showed improved investigator-assessed progression-free survival with first-line atezolizumab, vemurafenib, and cobimetinib (atezolizumab group) versus placebo, vemurafenib, and cobimetinib (control gro
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2647 (2019)
Domestication and breeding have created productive crops that are adapted to the climatic conditions of their growing regions. Initially, this process solely relied on the frequent occurrence of spontaneous mutations and the recombination of resultan
Externí odkaz:
https://doaj.org/article/71e38eb6eb1b4f9180cb8c109bae36ba
Autor:
Elena K. Khlestkina, Alex V. Kochetov, Stefan Hiekel, Christian Hertig, Ekaterina V. Kolosovskaya, Jochen Kumlehn, Ingrid Otto, Sophia V. Gerasimova, Anna M. Korotkova
Publikováno v:
BMC Plant Biology, Vol 20, Iss S1, Pp 1-12 (2020)
BMC Plant Biology
BMC Plant Biology
Background The naked caryopsis character in barley is a domestication-associated trait defined by loss-of-function of the NUD gene. The functional NUD gene encodes an Apetala 2/Ethylene-Response Factor (AP2/ERF) controlling the formation of a cementi
Autor:
Jochen Kumlehn, Christian Hertig, D. R. Mańkowski, A. M. Linkiewicz, Krzysztof Michalski, Janusz Zimny
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7038, p 7038 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences
Volume 22
Issue 13
Cas endonuclease-mediated genome editing provides a long-awaited molecular biological approach to the modification of predefined genomic target sequences in living organisms. Although cas9/guide (g)RNA constructs are straightforward to assemble and c