Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Christian, Henneberger"'
Autor:
Lorenzo Squadrani, Carlos Wert-Carvajal, Daniel Müller-Komorowska, Kirsten Bohmbach, Christian Henneberger, Pietro Verzelli, Tatjana Tchumatchenko
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Astrocytes play a key role in the regulation of synaptic strength and are thought to orchestrate synaptic plasticity and memory. Yet, how specifically astrocytes and their neuroactive transmitters control learning and memory is currently an
Externí odkaz:
https://doaj.org/article/77e8b030752b4a83b95fef24fe8dbf8c
Publikováno v:
eLife, Vol 13 (2024)
Ischemia leads to a severe dysregulation of glutamate homeostasis and excitotoxic cell damage in the brain. Shorter episodes of energy depletion, for instance during peri-infarct depolarizations, can also acutely perturb glutamate signaling. It is le
Externí odkaz:
https://doaj.org/article/5cfb633bde8249dca841a174ef157cc7
Autor:
Kirsten Bohmbach, Nicola Masala, Eva M. Schönhense, Katharina Hill, André N. Haubrich, Andreas Zimmer, Thoralf Opitz, Heinz Beck, Christian Henneberger
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
How glial cells like astrocytes shape complex brain functions remains unclear. Here, the authors identified an astrocyte-mediated excitatory signaling loop between neurons and their own dendritic signal integration that supports spatial memory.
Externí odkaz:
https://doaj.org/article/54da0d4cedc44b3692f8f04a7d0a5037
Autor:
Linda Patt, Dario Tascio, Catia Domingos, Aline Timmermann, Ronald Jabs, Christian Henneberger, Christian Steinhäuser, Gerald Seifert
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13490 (2023)
NG2 glia receive synaptic input from neurons, but the functional impact of this glial innervation is not well understood. In the developing cerebellum and somatosensory cortex the GABAergic input might regulate NG2 glia differentiation and myelinatio
Externí odkaz:
https://doaj.org/article/b9be56e1a4a24ac9a5d6572ee9b03a2d
Autor:
Cátia Domingos, Franziska E. Müller, Stefan Passlick, Dagmar Wachten, Evgeni Ponimaskin, Martin K. Schwarz, Susanne Schoch, André Zeug, Christian Henneberger
Publikováno v:
Cells, Vol 12, Iss 2, p 331 (2023)
Structural changes of astrocytes and their perisynaptic processes occur in response to various physiological and pathophysiological stimuli. They are thought to profoundly affect synaptic signalling and neuron-astrocyte communication. Understanding t
Externí odkaz:
https://doaj.org/article/5a44943070434b2c8ecc0c48ef588060
Publikováno v:
Cells, Vol 11, Iss 19, p 3150 (2022)
The concept of the tripartite synapse describes the close interaction of pre- and postsynaptic elements and the surrounding astrocyte processes. For glutamatergic synapses, it is established that the presence of astrocytic processes and their structu
Externí odkaz:
https://doaj.org/article/ae8e406ed8f147f8b0883cd7958ebb26
Autor:
Daniel Minge, Cátia Domingos, Petr Unichenko, Charlotte Behringer, Alberto Pauletti, Stefanie Anders, Michel K. Herde, Andrea Delekate, Polina Gulakova, Susanne Schoch, Gabor C. Petzold, Christian Henneberger
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
The fine processes of single astrocytes can contact many thousands of synapses whose function they can modulate through bi-directional signaling. The spatial arrangement of astrocytic processes and neuronal structures is relevant for such interaction
Externí odkaz:
https://doaj.org/article/01476609db6c4d2cb092389cbc0e5087
Autor:
João Filipe Viana, João Luís Machado, Daniela Sofia Abreu, Alexandra Veiga, Sara Barsanti, Gabriela Tavares, Manuella Martins, Vanessa Morais Sardinha, Sónia Guerra‐Gomes, Cátia Domingos, Alberto Pauletti, Jérôme Wahis, Chen Liu, Corrado Calì, Christian Henneberger, Matthew G. Holt, João Filipe Oliveira
Publikováno v:
Glia 71(7), 1667-1682 (2023). doi:10.1002/glia.24362
Astrocytes are integral components of brain circuits, where they sense, process, and respond to surrounding activity, maintaining homeostasis and regulating synaptic transmission, the sum of which results in behavior modulation. These interactions ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ab4634e034ded0025122b7ee1a7786
https://doi.org/10.1002/glia.24362
https://doi.org/10.1002/glia.24362
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
High-affinity, Na+-dependent glutamate transporters are the primary means by which synaptically released glutamate is removed from the extracellular space. They restrict the spread of glutamate from the synaptic cleft into the perisynaptic space and
Externí odkaz:
https://doaj.org/article/f089a72e10c548b89c684added8fb4fa
Autor:
Michel K. Herde, Kirsten Bohmbach, Cátia Domingos, Natascha Vana, Joanna A. Komorowska-Müller, Stefan Passlick, Inna Schwarz, Colin J. Jackson, Dirk Dietrich, Martin K. Schwarz, Christian Henneberger
Publikováno v:
Cell Reports, Vol 32, Iss 12, Pp 108182- (2020)
Summary: Synaptically released glutamate is largely cleared by glutamate transporters localized on perisynaptic astrocyte processes. Therefore, the substantial variability of astrocyte coverage of individual hippocampal synapses implies that the effi
Externí odkaz:
https://doaj.org/article/db94c07843ce4150be52cf0a045b7c15