Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Christian, Graeff"'
Autor:
Olga Sokol, Laura Cella, Daria Boscolo, Felix Horst, Caterina Oliviero, Roberto Pacelli, Giuseppe Palma, Micol De Simoni, Manuel Conson, Mara Caroprese, Ulrich Weber, Christian Graeff, Katia Parodi, Marco Durante
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Sharp dose gradients and high biological effectiveness make ions such as 12C an ideal tool to treat deep-seated tumors, however, at the same time, sensitive to errors in the range prediction. Tumor safety margins mitigate these uncertainties
Externí odkaz:
https://doaj.org/article/434fe321c8574934960630f920251992
Autor:
Lennart Volz, Claire-Anne Reidel, Marco Durante, Yolanda Prezado, Christoph Schuy, Uli Weber, Christian Graeff
Publikováno v:
Instruments, Vol 7, Iss 2, p 18 (2023)
Particle minibeam therapy has demonstrated the potential for better healthy tissue sparing due to spatial fractionation of the delivered dose. Especially for heavy ions, the spatial fractionation could enhance the already favorable differential biolo
Externí odkaz:
https://doaj.org/article/ade6c8231a12421e9e8458fbe499e3c7
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Particle therapy is a rapidly growing field in cancer therapy. Worldwide, over 100 centers are in operation, and more are currently in construction phase. The interest in particle therapy is founded in the superior target dose conformity and healthy
Externí odkaz:
https://doaj.org/article/cdb2a5f7eecb4481b5f5c4144ee57da1
Autor:
Michelle Lis, Wayne Newhauser, Marco Donetti, Moritz Wolf, Timo Steinsberger, Athena Paz, Christian Graeff
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
PurposeThe purpose of this study was to validate the dosimetric performance of scanned ion beam deliveries with motion-synchronization to heterogenous targets.MethodsA 4D library of treatment plans, comprised of up to 10 3D sub-plans, was created wit
Externí odkaz:
https://doaj.org/article/090a489d7f6f4f5cac631d223fab5bc3
Autor:
Daria Boscolo, Daria Kostyleva, Mohammad Javad Safari, Vasiliki Anagnostatou, Juha Äystö, Soumya Bagchi, Tim Binder, Georgios Dedes, Peter Dendooven, Timo Dickel, Vasyl Drozd, Bernhard Franczack, Hans Geissel, Chiara Gianoli, Christian Graeff, Tuomas Grahn, Florian Greiner, Emma Haettner, Roghieh Haghani, Muhsin N. Harakeh, Felix Horst, Christine Hornung, Jan-Paul Hucka, Nasser Kalantar-Nayestanaki, Erika Kazantseva, Birgit Kindler, Ronja Knöbel, Natalia Kuzminchuk-Feuerstein, Bettina Lommel, Ivan Mukha, Chiara Nociforo, Shunki Ishikawa, Giulio Lovatti, Munetaka Nitta, Ikechi Ozoemelam, Stephane Pietri, Wolfgang R. Plaß, Andrej Prochazka, Sivaji Purushothaman, Claire-Anne Reidel, Heidi Roesch, Fabio Schirru, Christoph Schuy, Olga Sokol, Timo Steinsberger, Yoshiki K. Tanaka, Isao Tanihata, Peter Thirolf, Walter Tinganelli, Bernd Voss, Uli Weber, Helmut Weick, John S. Winfield, Martin Winkler, Jianwei Zhao, Christoph Scheidenberger, Katia Parodi, Marco Durante, the Super-FRS Experiment Collaboration
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Several techniques are under development for image-guidance in particle therapy. Positron (β+) emission tomography (PET) is in use since many years, because accelerated ions generate positron-emitting isotopes by nuclear fragmentation in the human b
Externí odkaz:
https://doaj.org/article/33b862ca45f24852bdc997b710c3a1aa
Autor:
Timo Steinsberger, Marco Donetti, Michelle Lis, Lennart Volz, Moritz Wolf, Marco Durante, Christian Graeff
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 115:1257-1268
Treatment of locally advanced lung cancer is limited by toxicity and insufficient local control. Particle therapy could enable more conformal treatment than intensity modulated photon therapy, but is challenged by irregular tumor motion, associated r
Autor:
Michelle Lis, Wayne Newhauser, Marco Donetti, Moritz Wolf, Timo Steinsberger, Athena Paz, Marco Durante, Christian Graeff
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundQuality management and safety are integral to modern radiotherapy. New radiotherapy technologies require new consensus guidelines on quality and safety. Established analysis strategies, such as the failure modes and effects analysis (FMEA)
Externí odkaz:
https://doaj.org/article/3cad391e3b524b2bbdc7bb4a285a925e
Autor:
Vincenzo Patera, Yolanda Prezado, Faical Azaiez, Giuseppe Battistoni, Diego Bettoni, Sytze Brandenburg, Aleksandr Bugay, Giacomo Cuttone, Denis Dauvergne, Gilles de France, Christian Graeff, Thomas Haberer, Taku Inaniwa, Sebastien Incerti, Elena Nasonova, Alahari Navin, Marco Pullia, Sandro Rossi, Charlot Vandevoorde, Marco Durante
Publikováno v:
Frontiers in Physics, Vol 8 (2020)
Biomedical applications at high-energy particle accelerators have always been an important section of the applied nuclear physics research. Several new facilities are now under constructions or undergoing major upgrades. While the main goal of these
Externí odkaz:
https://doaj.org/article/50a6ae4399ed4f5cb80a537ba949f652
Publikováno v:
Applied Sciences, Vol 11, Iss 15, p 6806 (2021)
Radiation therapy (RT) is a constantly evolving therapeutic technique; improvements are continuously being introduced for both methodological and practical aspects. Among the features that have undergone a huge evolution in recent decades, dose calcu
Externí odkaz:
https://doaj.org/article/af4ad46400a74921bd213a1f69906e52
Autor:
Antje-Christin Knopf, Katarzyna Czerska, Francesco Fracchiolla, Christian Graeff, Silvia Molinelli, Ilaria Rinaldi, Antoni Rucincki, Edmond Sterpin, Kristin Stützer, Petra Trnkova, Ye Zhang, Joe Y Chang, Huan Giap, Wei Liu, Steven E Schild, Charles B. Simone, Antony J Lomax, Arturs Meijers
Publikováno v:
Radiotherapy and Oncology, Vol. 169, no.00, p. 77-85 (2022)
Radiotherapy & Oncology, 169
Radiotherapy and Oncology 169(2022), 77-85
Radiotherapy and oncology 169, 77-85 (2022). doi:10.1016/j.radonc.2022.02.018
Radiotherapy & Oncology, 169
Radiotherapy and Oncology 169(2022), 77-85
Radiotherapy and oncology 169, 77-85 (2022). doi:10.1016/j.radonc.2022.02.018
4D multi-image-based (4DMIB) optimization is a form of robust optimization where different uncertainty scenarios, due to anatomy variations, are considered via multiple image sets (e.g., 4DCT). In this review, we focused on providing an overview of d