Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Christian, Goosmann"'
FlhE functions as a chaperone to prevent formation of periplasmic flagella in Gram-negative bacteria
Autor:
Manuel Halte, Ekaterina P. Andrianova, Christian Goosmann, Fabienne F. V. Chevance, Kelly T. Hughes, Igor B. Zhulin, Marc Erhardt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The bacterial flagellum, which facilitates motility, is composed of ~20 structural proteins organized into a long extracellular filament connected to a cytoplasmic rotor-stator complex via a periplasmic rod. Flagellum assembly is regulated b
Externí odkaz:
https://doaj.org/article/1fae30fb18c340a380f649d28be01a86
Autor:
Stefanie Koster, Rajendra Kumar Gurumurthy, Naveen Kumar, Pon Ganish Prakash, Jayabhuvaneshwari Dhanraj, Sofia Bayer, Hilmar Berger, Shilpa Mary Kurian, Marina Drabkina, Hans-Joachim Mollenkopf, Christian Goosmann, Volker Brinkmann, Zachary Nagel, Mandy Mangler, Thomas F. Meyer, Cindrilla Chumduri
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Here, Koster et al., model human papillomavirus and Chlamydia coinfection dynamics in patient-derived ectocervical organoids, and characterize the effects of multiple infections in the cellular microenvironment, potentially contributing to neoplasia.
Externí odkaz:
https://doaj.org/article/2fb21c954d7549fe9ee43a376dd4e07a
Autor:
Xuhui Zheng, Gerben Marsman, Keenan A. Lacey, Jessica R. Chapman, Christian Goosmann, Beatrix M. Ueberheide, Victor J. Torres
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The pathogen Staphylococcus aureus releases several pore-forming toxins, termed leukocidins, that kill immune cells. Here, Zheng et al. show that the retention of a leukocidin on bacterial cells and its release are modulated by lipoteichoic acid and
Externí odkaz:
https://doaj.org/article/5b83eef527514fa19ea34ec32cc64ae8
Autor:
Julian Heuberger, Jakob Trimpert, Daria Vladimirova, Christian Goosmann, Manqiang Lin, Rosa Schmuck, Hans‐Joachim Mollenkopf, Volker Brinkmann, Frank Tacke, Nikolaus Osterrieder, Michael Sigal
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 4, Pp n/a-n/a (2021)
Abstract SARS‐CoV‐2, the agent that causes COVID‐19, invades epithelial cells, including those of the respiratory and gastrointestinal mucosa, using angiotensin‐converting enzyme‐2 (ACE2) as a receptor. Subsequent inflammation can promote r
Externí odkaz:
https://doaj.org/article/5396e49c30f44e5e8e0a119b1c47a08f
Autor:
Ludovico P. Sepe, Kimberly Hartl, Amina Iftekhar, Hilmar Berger, Naveen Kumar, Christian Goosmann, Sascha Chopra, Sven Christian Schmidt, Rajendra Kumar Gurumurthy, Thomas F. Meyer, Francesco Boccellato
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Carcinoma of the gallbladder (GBC) is the most frequent tumor of the biliary tract. Despite epidemiological studies showing a correlation between chronic infection with Salmonella enterica Typhi/Paratyphi A and GBC, the underlying molecular
Externí odkaz:
https://doaj.org/article/1ae6b72acc6640248948774430ee9160
Publikováno v:
Cell Reports, Vol 23, Iss 3, Pp 756-767 (2018)
Summary: Proteins of the stomatin/prohibitin/flotillin/HfIK/C (SPFH) family are membrane-anchored and perform diverse cellular functions in different organelles. Here, we investigate the SPFH proteins of the murine malaria model parasite Plasmodium b
Externí odkaz:
https://doaj.org/article/33dedb0300e045e7b1fd081da48ceca2
Autor:
Pablo Suárez-Cortés, Giulia Costa, Manuela Andres, Daniel Eyermann, Cornelia Kreschel, Liane Spohr, Christian Goosmann, Volker Brinkmann, Elena A. Levashina
Fluorescence reporter strains of human malaria parasites are powerful tools to study the interaction of the parasites with both human and mosquito hosts. However, low fluorescence intensity in transmission-relevant parasite stages and the choice of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1610981246e1fec20ad0be8a2b27f33c
https://doi.org/10.1101/2023.05.23.542002
https://doi.org/10.1101/2023.05.23.542002
Autor:
Dior Beerens, Sandra Franch-Arroyo, Timothy J. Sullivan, Christian Goosmann, Volker Brinkmann, Emmanuelle Charpentier
Publikováno v:
Viruses, Vol 13, Iss 4, p 612 (2021)
Bacteriophages exert strong evolutionary pressure on their microbial hosts. In their lytic lifecycle, complete bacterial subpopulations are utilized as hosts for bacteriophage replication. However, during their lysogenic lifecycle, bacteriophages can
Externí odkaz:
https://doaj.org/article/3a262b2a412141c6868c3dd4694ce4d2
Publikováno v:
Development
Proven roles for hemocytes (blood cells) have expanded beyond the control of infections in Drosophila. Despite this, the crucial role of hemocytes in post-embryonic development has long thought to be limited to control of microorganisms during metamo
Autor:
Kathleen D. Metzler, Christian Goosmann, Aleksandra Lubojemska, Arturo Zychlinsky, Venizelos Papayannopoulos
Publikováno v:
Cell Reports, Vol 8, Iss 3, Pp 883-896 (2014)
Neutrophils contain granules loaded with antimicrobial proteins and are regarded as impermeable organelles that deliver cargo via membrane fusion. However, during the formation of neutrophil extracellular traps (NETs), neutrophil elastase (NE) transl
Externí odkaz:
https://doaj.org/article/c05456111b6543e59c62a14bc2623df7