Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Christian, Gervais"'
Autor:
Matthew Stuible, Joseph D. Schrag, Joey Sheff, Daria Zoubchenok, Simon Lord-Dufour, Brian Cass, Denis L’Abbé, Alex Pelletier, Martin A. Rossotti, Jamshid Tanha, Christian Gervais, Roger Maurice, Majida El Bakkouri, Mauro Acchione, Yves Durocher
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract SARS-CoV-2 subunit vaccines continue to be the focus of intense clinical development worldwide. Protein antigens in these vaccines most commonly consist of the spike ectodomain fused to a heterologous trimerization sequence, designed to mimi
Externí odkaz:
https://doaj.org/article/dc399963cdec43a6ac763c16fa63044f
Autor:
Bassel Akache, Tyler M. Renner, Matthew Stuible, Nazanin Rohani, Yuneivy Cepero-Donates, Lise Deschatelets, Renu Dudani, Blair A. Harrison, Christian Gervais, Jennifer J. Hill, Usha D. Hemraz, Edmond Lam, Sophie Régnier, Anne E. G. Lenferink, Yves Durocher, Michael J. McCluskie
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-7 (2022)
Abstract Using our strongly immunogenic SmT1 SARS-CoV-2 spike antigen platform, we developed antigens based on the Beta & Delta variants of concern (VOC). These antigens elicited higher neutralizing antibody activity to the corresponding variant than
Externí odkaz:
https://doaj.org/article/d6403fda9ca74d4599cc113bbc9a49d9
Autor:
Martin A. Rossotti, Henk van Faassen, Anh T. Tran, Joey Sheff, Jagdeep K. Sandhu, Diana Duque, Melissa Hewitt, Xiaoxue Wen, Jegarubee Bavananthasivam, Saina Beitari, Kevin Matte, Geneviève Laroche, Patrick M. Giguère, Christian Gervais, Matthew Stuible, Julie Guimond, Sylvie Perret, Greg Hussack, Marc-André Langlois, Yves Durocher, Jamshid Tanha
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-19 (2022)
Isolation and extensive characterization of a collection of 37 anti-SARS-CoV-2 spike glycoprotein nanobodies show broad neutralization efficacies in vitro and in vivo in a hamster model of SARS-CoV-2 infection.
Externí odkaz:
https://doaj.org/article/2f48dc9abf474ef9b75e5e6b1b33d3f4
Autor:
Abdelhadi Djaïleb, Étienne Lavallée, Megan-Faye Parker, Marie-Pierre Cayer, Florence Desautels, Marie Joëlle de Grandmont, Matthew Stuible, Christian Gervais, Yves Durocher, Sylvie Trottier, Denis Boudreau, Jean-Francois Masson, Danny Brouard, Joelle N. Pelletier
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionEarly in the COVID-19 pandemic, reagent availability was not uniform, and infrastructure had to be urgently adapted to undertake COVID-19 surveillance.MethodsBefore the validation of centralized testing, two enzyme-linked immunosorbent as
Externí odkaz:
https://doaj.org/article/2871f1688d804235ae4c973f9907ee41
Autor:
Bassel Akache, Tyler M. Renner, Anh Tran, Lise Deschatelets, Renu Dudani, Blair A. Harrison, Diana Duque, Julie Haukenfrers, Martin A. Rossotti, Francis Gaudreault, Usha D. Hemraz, Edmond Lam, Sophie Régnier, Wangxue Chen, Christian Gervais, Matthew Stuible, Lakshmi Krishnan, Yves Durocher, Michael J. McCluskie
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract The huge worldwide demand for vaccines targeting SARS-CoV-2 has necessitated the continued development of novel improved formulations capable of reducing the burden of the COVID-19 pandemic. Herein, we evaluated novel protein subunit vaccine
Externí odkaz:
https://doaj.org/article/9618e29b6e8e4f74b75065bea762626c
Autor:
Maryam Hojjat Jodaylami, Abdelhadi Djaïleb, Pierre Ricard, Étienne Lavallée, Stella Cellier-Goethebeur, Megan-Faye Parker, Julien Coutu, Matthew Stuible, Christian Gervais, Yves Durocher, Florence Desautels, Marie-Pierre Cayer, Marie Joëlle de Grandmont, Samuel Rochette, Danny Brouard, Sylvie Trottier, Denis Boudreau, Joelle N. Pelletier, Jean-Francois Masson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract SARS-CoV-2 variants of concern (VOCs) have emerged worldwide, with implications on the spread of the pandemic. Characterizing the cross-reactivity of antibodies against these VOCs is necessary to understand the humoral response of non-hospit
Externí odkaz:
https://doaj.org/article/a83b93cecef64506a2384cd39a901c51
Autor:
Karen Colwill, Yannick Galipeau, Matthew Stuible, Christian Gervais, Corey Arnold, Bhavisha Rathod, Kento T Abe, Jenny H Wang, Adrian Pasculescu, Mariam Maltseva, Lynda Rocheleau, Martin Pelchat, Mahya Fazel‐Zarandi, Mariam Iskilova, Miriam Barrios‐Rodiles, Linda Bennett, Kevin Yau, François Cholette, Christine Mesa, Angel X Li, Aimee Paterson, Michelle A Hladunewich, Pamela J Goodwin, Jeffrey L Wrana, Steven J Drews, Samira Mubareka, Allison J McGeer, John Kim, Marc‐André Langlois, Anne‐Claude Gingras, Yves Durocher
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 3, Pp n/a-n/a (2022)
Abstract Objectives Antibody testing against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has been instrumental in detecting previous exposures and analyzing vaccine‐elicited immune responses. Here, we describe a scalable soluti
Externí odkaz:
https://doaj.org/article/5e0ee81ad5a14b2c90b3b4fd0393afdc
Autor:
Monica Bubenik, Pavel Mader, Philippe Mochirian, Fréderic Vallée, Jillian Clark, Jean-François Truchon, Alexander L. Perryman, Victor Pau, Igor Kurinov, Karl E. Zahn, Marie-Eve Leclaire, Robert Papp, Marie-Claude Mathieu, Martine Hamel, Nicole M. Duffy, Claude Godbout, Matias Casas-Selves, Jean-Pierre Falgueyret, Prasamit S. Baruah, Olivier Nicolas, Rino Stocco, Hugo Poirier, Giovanni Martino, Alexanne Bonneau Fortin, Anne Roulston, Amandine Chefson, Stéphane Dorich, Miguel St-Onge, Purvish Patel, Charles Pellerin, Stéphane Ciblat, Thomas Pinter, Francis Barabé, Majida El Bakkouri, Paranjay Parikh, Christian Gervais, Agnel Sfeir, Yael Mamane, Stephen J. Morris, W. Cameron Black, Frank Sicheri, Michel Gallant
Publikováno v:
Journal of Medicinal Chemistry. 65:13198-13215
Autor:
Maryam Hojjat Jodaylami, Abdelhadi Djaïleb, Pierre Ricard, Étienne Lavallée, Stella Cellier-Goetghebeur, Megan-Faye Parker, Julien Coutu, Matthew Stuible, Christian Gervais, Yves Durocher, Florence Desautels, Marie-Pierre Cayer, Marie Joëlle de Grandmont, Samuel Rochette, Danny Brouard, Sylvie Trottier, Denis Boudreau, Joelle N. Pelletier, Jean-Francois Masson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/102a975fa01342808f18935407920293
Autor:
Malama Chisanga, Matthew Stuible, Christian Gervais, Denis L'Abbé, Brian Cass, Louis Bisson, Alex Pelletier, Simon Lord-Dufour, Yves Durocher, Denis Boudreau, Sylvie Trottier, Joelle N. Pelletier, Jean-Francois Masson
Publikováno v:
Sensors & Diagnostics. 1:851-866
Monitoring antibody response to SARS-CoV-2 is critical for assessing the humoral response, especially important considering the emergence of multiple SARS-CoV-2 variants of concern (VOCs).