Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Christian, Darne"'
1
Akademický článek
Continuous Long-Term Exposure to Low Concentrations of MWCNTs Induces an Epithelial-Mesenchymal Transition in BEAS-2B Cells
Autor: Hélène Barthel, Christian Darne, Laurent Gaté, Athanase Visvikis, Carole Seidel
Publikováno v: Nanomaterials, Vol 11, Iss 7, p 1742 (2021)
In the field of nanotechnology, the use of multi-walled carbon nanotubes (MWCNTs) is growing. Pulmonary exposure during their production, use, and handling is raising concerns about their potential adverse health effects. The purpose of this study is
Externí odkaz: https://doaj.org/article/3d619a81590c45c58defc26a6994f541
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2
Continuous Long-Term Exposure to Low Concentrations of MWCNTs Induces an Epithelial-Mesenchymal Transition in BEAS-2B Cells
Autor: Carole Seidel, Hélène Barthel, Christian Darne, Athanase Visvikis, Laurent Gaté
Publikováno v: Nanomaterials, Vol 11, Iss 1742, p 1742 (2021)
Nanomaterials
Volume 11
Issue 7
In the field of nanotechnology, the use of multi-walled carbon nanotubes (MWCNTs) is growing. Pulmonary exposure during their production, use, and handling is raising concerns about their potential adverse health effects. The purpose of this study is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e2b95225467c3d683489276778d25fc
https://www.mdpi.com/2079-4991/11/7/1742
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3
Akademický článek
In Vitro Study of Mutagenesis Induced by Crocidolite-Exposed Alveolar Macrophages NR8383 in Cocultured Big Blue Rat2 Embryonic Fibroblasts
Autor: Yves Guichard, Laurent Gaté, Christian Darne, Marie-Claire Bottin, Cristina Langlais, Jean-Claude Micillino, Michèle Goutet, Schmit Julien, Binet Stéphane
Publikováno v: Journal of Toxicology, Vol 2010 (2010)
Asbestos-induced mutagenicity in the lung may involve reactive oxygen/nitrogen species (ROS/RNS) released by alveolar macrophages. With the aim of proposing an alternative in vitro mutagenesis test, a coculture system of rat alveolar macrophages (NR8
Externí odkaz: https://doaj.org/article/2f276caf0b5f471bb5b73647a2660f17
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5
In vitro cell transformation induced by synthetic amorphous silica nanoparticles
Autor: Yves Guichard, Carole Seidel, Laurent Gaté, Christian Darne, Léa Marpeaux, Anaïs Kirsch, Aurélie Remy, Caroline Fontana
Publikováno v: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 823:22-27
Synthetic amorphous silica nanoparticles (SAS) are among the most widely produced and used nanomaterials, but little is known about their carcinogenic potential. This study aims to evaluate the ability of four different SAS, two precipitated, NM-200
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d754ad7835ced401e299905ed7188e3a
https://doi.org/10.1016/j.mrgentox.2017.08.002
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6
A non-damaging purification method: decoupling the toxicity of multi-walled carbon nanotubes and their associated metal impurities
Autor: Yves Guichard, François Le Normand, Fabrice Valsaque, Alexandre Desforges, Jérôme Gleize, Dominique Begin, Christian Darne, Jaafar Ghanbaja, Caroline Fontana, Nawal Berrada, Brigitte Vigolo, Laurent Gaté
Publikováno v: Environmental science‎.Nano
Environmental science‎.Nano, Royal Society of Chemistry, 2019, 6 (6), pp.1852-1865. ⟨10.1039/c8en01276h⟩
Environmental science‎.Nano, 2019, 6 (6), pp.1852-1865. ⟨10.1039/c8en01276h⟩
International audience; Multi walled carbon nanotubes (MWCNTs) are purified by a gas-phase method allowing selective removal of the metallic impurities (Fe and Al catalyst residues) while the MWCNTs remain untouched. Contrary to works using standard
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c523f4d887bca7ed030bed03c23bde1
https://hal.univ-lorraine.fr/hal-02270532
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7
Epigenetic changes in the early stage of silica-induced cell transformation
Autor: Carole Seidel, Laurent Gaté, Yves Guichard, Anaïs Kirsch, Christian Darne, Caroline Fontana, Athanase Visvikis, Aurélie Remy
Publikováno v: Nanotoxicology
Nanotoxicology, Taylor & Francis, 2017, 11 (7), pp.923-935. ⟨10.1080/17435390.2017.1382599⟩
International audience; The increasing use of nanomaterials in numerous domains has led to growing concern about their potential toxicological properties, and the potential risk to human health posed by silica nanoparticles remains under debate. Rece
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c1eabef7d6641657455503851e3508
https://pubmed.ncbi.nlm.nih.gov/28958182
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8
Cytotoxicity and Genotoxicity of Panel of Single- and Multiwalled Carbon Nanotubes:In VitroEffects on Normal Syrian Hamster Embryo and Immortalized V79 Hamster Lung Cells
Autor: Stéphane Binet, Yves Guichard, C. Coulais, F. Terzetti, Caroline Fontana, Laurent Gaté, Christian Darne
Publikováno v: Journal of Toxicology, Vol 2014 (2014)
Journal of Toxicology
Carbon nanotubes (CNTs) belong to a specific class of nanomaterials with unique properties. Because of their anticipated use in a wide range of industrial applications, their toxicity is of increasing concern. In order to determine whether specific p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e0a8bde126a1d5c88d50ade4c49559
https://doi.org/10.1155/2014/872195
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9
Genotoxicity of styrene-7,8-oxide and styrene in Fisher 344 rats: A 4-week inhalation study
Autor: Yves Guichard, Cristina Langlais, Hervé Nunge, Frédéric Cosnier, Jean-Claude Micillino, Stéphane Binet, Sylvie Sébillaud, Laurent Gate, Christian Darne
Publikováno v: Toxicology Letters. 211:211-219
The cytogenetic alterations in leukocytes and the increased risk for leukemia, lymphoma, or all lymphohematopoietic cancer observed in workers occupationally exposed to styrene have been associated with its hepatic metabolisation into styrene-7,8-oxi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faab1c36ec50d07c5b4b296aee29efc9
https://doi.org/10.1016/j.toxlet.2012.03.796
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10
In vitro comet and micronucleus assays do not predict morphological transforming effects of silica particles in Syrian Hamster Embryo cells
Autor: Yves Guichard, Christian Darne, Laurent Gaté, F. Terzetti, Caroline Fontana, Stéphane Binet, C. Coulais
Publikováno v: Mutation research. Genetic toxicology and environmental mutagenesis. 796
Crystalline silica particles and asbestos have both been classified as carcinogenic by the International Agency for Research on Cancer (IARC). However, because of the limited data available, amorphous silica was not classifiable. In vitro, the carcin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7c4ca15d6b5244fa39c5e9e56a2dbf
https://pubmed.ncbi.nlm.nih.gov/26778506
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