Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Christian, Antoni"'
Autor:
Jorge Maspero, Guy Brusselle, Parameswaran Nair, Hongjie Zhu, Ariel Teper, Neil M.H. Graham, Asif Khan, Mario Castro, Lawrence Sher, Bolanle Akinlade, Heribert Staudinger, Brian N. Swanson, Gianluca Pirozzi, Christian Antoni, Klaus F. Rabe, Marcella Ruddy, Jingdong Chao, Nikhil Amin, Neil Stahl, Jennifer D. Hamilton, George D. Yancopoulos
Publikováno v:
New England Journal of Medicine. 378:2475-2485
Background Dupilumab is a fully human anti–interleukin-4 receptor α monoclonal antibody that blocks both interleukin-4 and interleukin-13 signaling. Its effectiveness in reducing oral glucocorticoid use in patients with severe asthma while maintai
Autor:
Christian Antoni, Corinne Esperet, Raphael Bejuit, Ganesh Raghu, Peter Wung, Bruno Crestani, Luca Richeldi, Christina Soubrane
Publikováno v:
The European respiratory journal. 52(6)
A phase 2b trial (NCT02345070) was conducted to evaluate the efficacy and safety of two dose levels/regimens of SAR156597 (a bispecific IgG4 antibody that binds and neutralises both circulating interleukin-4 and interleukin-13), in comparison with pl
Publikováno v:
The Journal of allergy and clinical immunology. 140(3)
Autor:
Möllerop, Christian Antoni
There is a lack of a feminist perspective within general theories of international relations, but also in those documents that represents the basis for foreign policy, and a feminist assessment of the same. Assessment-tools for foreign policy that co
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-178150
Autor:
Heiko Bruns, Robert L. Modlin, Philipp Schauenberg, Peter Kern, Steffen Stenger, Georg Härter, Christian Antoni, Christoph Meinken
Publikováno v:
Journal of Clinical Investigation. 119:1167-1177
The incidence of tuberculosis is increased during treatment of autoimmune diseases with anti-TNF antibodies. This is a significant clinical complication, but also provides a unique model to study immune mechanisms in human tuberculosis. Given the key
Autor:
Peter Charles, Michael J. Elliott, Diana Davis, Alison Potter, Joachim R. Kalden, Christian Antoni, Ferdinand C. Breedveld, Josef S. Smolen, Gabriele Eberl, Kim deWoody, Marc Feldmann, Ravinder N. Maini
Publikováno v:
The Journal of Immunology. 163:1521-1528
Treatment with a chimeric mAb to TNF-α has been shown to suppress inflammation and improve patient well-being in rheumatoid arthritis (RA), but the mechanisms of action of such treatment have not been fully explored. Here we show that in vivo admini
Autor:
Dhavalkumar D. Patel, C. Stephen Foster, Kristine Rose, Naomi S. Falk, Zoe Diana Draelos, Quan Dong Nguyen, Christian Antoni, Paul P. Tak, David S. Chu, Rosa Y. Kim, Andrew M Wright, Thaddeus P. Dryja, Irina Koroleva, Gerard Bruin, David Callanan, Asifa Haider, Wolfgang Hueber, Michael H. Gold, C. Michael Samson, Patrick Durez, Juan J. Gomez-Reino, Franco Di Padova
Publikováno v:
Science translational medicine, 2(52). American Association for the Advancement of Science
Interleukin-17A (IL-17A) is elaborated by the T helper 17 (T(H)17) subset of T(H) cells and exhibits potent proinflammatory properties in animal models of autoimmunity, including collagen-induced arthritis, experimental autoimmune encephalomyelitis,
Autor:
Arthur, Kavanaugh, Christian, Antoni, Philip, Mease, Dafna, Gladman, Songkai, Yan, Mohan, Bala, Bei, Zhou, Lisa T, Dooley, Anna, Beutler, Cynthia, Guzzo, Gerald G, Krueger
Publikováno v:
The Journal of rheumatology. 33(11)
To examine the effect of infliximab on employment status, time lost from work, and productivity in a double-blind, placebo-controlled study of patients with active psoriatic arthritis (PsA).Two hundred adult patients with PsA were randomized to intra
Autor:
Dafna D, Gladman, Philip J, Mease, Gerald, Krueger, Désirée M F M, van der Heidje, Christian, Antoni, Philip S, Helliwell, Arthur F, Kavanaugh, Peter, Nash, Christopher T, Ritchlin, C Vibeke, Strand, William, Taylor
Publikováno v:
The Journal of rheumatology. 32(11)
Recent advances in biologic therapies have provided hope for patients with psoriatic arthritis (PsA). However, studies have been hampered by the lack of acceptable and validated outcome measures. This article reviews outcome measures used in the asse
Autor:
Joachim R, Kalden, Christian, Antoni, Jose M, Alvaro-Gracia, Bernard, Combe, Paul, Emery, Joel M, Kremer, C Vibeke, Strand, Piet, Van Riel, Josef S, Smolen
Publikováno v:
The Journal of rheumatology. 32(8)
An Expert Panel Meeting was held in May 2004 to assess experience with combination therapy with leflunomide and biological agents in the treatment of rheumatoid arthritis (RA), to identify both optimal use of such combinations and precautions for use