Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Christiaan van Ooij"'
Publikováno v:
mBio, Vol 15, Iss 1 (2024)
ABSTRACTMalaria parasites alter multiple properties of the host erythrocyte by exporting proteins into the host cell. Many exported proteins contain a five-amino acid motif called the Plasmodium export element (PEXEL) that is cleaved by the parasite
Externí odkaz:
https://doaj.org/article/42d4fced97374e76b7ebac8126bedc36
Autor:
Tansy Vallintine, Christiaan van Ooij
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT Malaria parasites modify their host erythrocyte in multiple ways, leading to changes in the deformability, adhesiveness, and permeability of the host erythrocyte. Most of these changes are mediated by proteins exported from the parasite to t
Externí odkaz:
https://doaj.org/article/19bbe789f24647ac86f1ff3fc08966e1
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Malaria parasites are unicellular eukaryotic pathogens that develop through a complex lifecycle involving two hosts, an anopheline mosquito and a vertebrate host. Throughout this lifecycle, the parasite encounters widely differing conditions and surv
Externí odkaz:
https://doaj.org/article/c72e313b8ae8429f9bb6b2f2d1bd2d50
Autor:
Margarida Ressurreição, James A Thomas, Stephanie D Nofal, Christian Flueck, Robert W Moon, David A Baker, Christiaan van Ooij
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235798 (2020)
During the course of the asexual erythrocytic stage of development, Plasmodium spp. parasites undergo a series of morphological changes and induce alterations in the host cell. At the end of this stage, the parasites egress from the infected cell, af
Externí odkaz:
https://doaj.org/article/80f4886ea7234c70a100a8f50abd34f2
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Successful establishment of CRISPR/Cas9 genome editing technology in Plasmodium spp. has provided a powerful tool to transform Plasmodium falciparum into a genetically more tractable organism. Conditional gene regulation approaches are requi
Externí odkaz:
https://doaj.org/article/d5e83861321b4d35ab33c4b412310346
Autor:
Emma S Sherling, Ellen Knuepfer, Joseph A Brzostowski, Louis H Miller, Michael J Blackman, Christiaan van Ooij
Publikováno v:
eLife, Vol 6 (2017)
Merozoites of the protozoan parasite responsible for the most virulent form of malaria, Plasmodium falciparum, invade erythrocytes. Invasion involves discharge of rhoptries, specialized secretory organelles. Once intracellular, parasites induce incre
Externí odkaz:
https://doaj.org/article/bb952e33652c46da9d8642ac43d29c35
Autor:
Aurélie Fougère, Andrew P Jackson, Dafni Paraskevi Bechtsi, Joanna A M Braks, Takeshi Annoura, Jannik Fonager, Roberta Spaccapelo, Jai Ramesar, Séverine Chevalley-Maurel, Onny Klop, Annelies M A van der Laan, Hans J Tanke, Clemens H M Kocken, Erica M Pasini, Shahid M Khan, Ulrike Böhme, Christiaan van Ooij, Thomas D Otto, Chris J Janse, Blandine Franke-Fayard
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006128 (2017)
[This corrects the article DOI: 10.1371/journal.ppat.1005917.].
Externí odkaz:
https://doaj.org/article/c2c38d1a6c904cbaac48c2316a158103
Autor:
Aurélie Fougère, Andrew P Jackson, Dafni Paraskevi Bechtsi, Joanna A M Braks, Takeshi Annoura, Jannik Fonager, Roberta Spaccapelo, Jai Ramesar, Séverine Chevalley-Maurel, Onny Klop, Annelies M A van der Laan, Hans J Tanke, Clemens H M Kocken, Erica M Pasini, Shahid M Khan, Ulrike Böhme, Christiaan van Ooij, Thomas D Otto, Chris J Janse, Blandine Franke-Fayard
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006107 (2016)
[This corrects the article DOI: 10.1371/journal.ppat.1005917.].
Externí odkaz:
https://doaj.org/article/ec08579f63af4a1ba5b098efdaa08eea
Autor:
Aurélie Fougère, Andrew P Jackson, Dafni Paraskevi Bechtsi, Joanna A M Braks, Takeshi Annoura, Jannik Fonager, Roberta Spaccapelo, Jai Ramesar, Séverine Chevalley-Maurel, Onny Klop, Annelies M A van der Laan, Hans J Tanke, Clemens H M Kocken, Erica M Pasini, Shahid M Khan, Ulrike Böhme, Christiaan van Ooij, Thomas D Otto, Chris J Janse, Blandine Franke-Fayard
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1005917 (2016)
Many variant proteins encoded by Plasmodium-specific multigene families are exported into red blood cells (RBC). P. falciparum-specific variant proteins encoded by the var, stevor and rifin multigene families are exported onto the surface of infected
Externí odkaz:
https://doaj.org/article/18e245b6a4594c4c94809d78d35545b0
Autor:
Pamela A Tamez, Souvik Bhattacharjee, Christiaan van Ooij, N Luisa Hiller, Manuel Llinás, Bharath Balu, John H Adams, Kasturi Haldar
Publikováno v:
PLoS Pathogens, Vol 4, Iss 8, p e1000118 (2008)
Plasmodium falciparum is the protozoan parasite that causes the most virulent of human malarias. The blood stage parasites export several hundred proteins into their host erythrocyte that underlie modifications linked to major pathologies of the dise
Externí odkaz:
https://doaj.org/article/b796dcb1af6a448e945f1ecba50272b6