Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Christiaan P. J. de Kock"'
Autor:
Stan L. W. Driessens, Anna A. Galakhova, Djai B. Heyer, Isabel J. Pieterse, René Wilbers, Eline J. Mertens, Femke Waleboer, Tim S. Heistek, Loet Coenen, Julia R. Meijer, Sander Idema, Philip C. de Witt Hamer, David P. Noske, Christiaan P. J. de Kock, Brian R. Lee, Kimberly Smith, Jonathan T. Ting, Ed S. Lein, Huibert D. Mansvelder, Natalia A. Goriounova
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract GWAS have identified numerous genes associated with human cognition but their cell type expression profiles in the human brain are unknown. These genes overlap with human accelerated regions (HARs) implicated in human brain evolution and mig
Externí odkaz:
https://doaj.org/article/50832097a77b45fca91162348467e082
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 15 (2023)
Information transfer between principal neurons in neocortex occurs through (glutamatergic) synaptic transmission. In this focussed review, we provide a detailed overview on the strength of synaptic neurotransmission between pairs of excitatory neuron
Externí odkaz:
https://doaj.org/article/762a4867924848c48df5583221a79016
Autor:
Matthijs N. Oude Lohuis, Jean L. Pie, Pietro Marchesi, Jorrit S. Montijn, Christiaan P. J. de Kock, Cyriel M. A. Pennartz, Umberto Olcese
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
How primary sensory cortices contribute to decision making remains poorly understood. Here the authors report that increasing task demands extend the temporal window in which the primary visual cortex is required for detecting identical stimuli.
Externí odkaz:
https://doaj.org/article/4b69656efb054dd6bfc59378dedc6068
Autor:
Christiaan P. J. de Kock, Jean Pie, Anton W. Pieneman, Rebecca A. Mease, Arco Bast, Jason M. Guest, Marcel Oberlaender, Huibert D. Mansvelder, Bert Sakmann
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
In order to investigate the information encoded by spiking activity in different neuronal cell types in the primary somatosensory cortex, de Kock et al performed electrophysiological recordings in untrained rats. They demonstrated that an increase in
Externí odkaz:
https://doaj.org/article/545cc6b7f83a4daf9de820113342a7e0
Autor:
Joshua Obermayer, Antonio Luchicchi, Tim S. Heistek, Sybren F. de Kloet, Huub Terra, Bastiaan Bruinsma, Ouissame Mnie-Filali, Christian Kortleven, Anna A. Galakhova, Ayoub J. Khalil, Tim Kroon, Allert J. Jonker, Roel de Haan, Wilma D. J. van de Berg, Natalia A. Goriounova, Christiaan P. J. de Kock, Tommy Pattij, Huibert D. Mansvelder
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
VIP interneurons have been shown to disinhibit pyramidal neurons by inhibiting other interneuron types. Here, the authors report that ChAT-VIP subtype of interneurons directly excite pyramidal neurons in multiple layers via fast cholinergic neurotran
Externí odkaz:
https://doaj.org/article/59339fd0ec524e8d8a59a8fece53b4cb
Autor:
Matthijs N. Oude Lohuis, Jean L. Pie, Pietro Marchesi, Jorrit S. Montijn, Christiaan P. J. de Kock, Cyriel M. A. Pennartz, Umberto Olcese
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/852be8979df1479692b887079a6459eb
Autor:
Matthijs B. Verhoog, Joshua Obermayer, Christian A. Kortleven, René Wilbers, Jordi Wester, Johannes C. Baayen, Christiaan P. J. De Kock, Rhiannon M. Meredith, Huibert D. Mansvelder
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nicotinic acetylcholine receptors (nAChRs) are differentially expressed across cortical layers, yet it is unclear whether they show layer-specific effects on synaptic plasticity in the prefrontal cortex. Here, the authors compare nAChRs across L6 and
Externí odkaz:
https://doaj.org/article/dfb3fee0fe6243589a8dcbee3f84b457
Autor:
Joshua Obermayer, Antonio Luchicchi, Tim S. Heistek, Sybren F. de Kloet, Huub Terra, Bastiaan Bruinsma, Ouissame Mnie-Filali, Christian Kortleven, Anna A. Galakhova, Ayoub J. Khalil, Tim Kroon, Allert J. Jonker, Roel de Haan, Wilma D. J. van de Berg, Natalia A. Goriounova, Christiaan P. J. de Kock, Tommy Pattij, Huibert D. Mansvelder
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/a04239147e064305a9366bd3092f352a
Autor:
Roel de Haan, Judith Lim, Sven A. van der Burg, Anton W. Pieneman, Vinod Nigade, Huibert D. Mansvelder, Christiaan P. J. de Kock
Publikováno v:
Frontiers in Neural Circuits, Vol 12 (2018)
Selecting behavioral outputs in a dynamic environment is the outcome of integrating multiple information streams and weighing possible action outcomes with their value. Integration depends on the medial prefrontal cortex (mPFC), but how mPFC neurons
Externí odkaz:
https://doaj.org/article/ff9076949f3f4787a8de07c473fb1711
Autor:
Guy Eyal, Matthijs B. Verhoog, Guilherme Testa-Silva, Yair Deitcher, Ruth Benavides-Piccione, Javier DeFelipe, Christiaan P. J. de Kock, Huibert D. Mansvelder, Idan Segev
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
We present detailed models of pyramidal cells from human neocortex, including models on their excitatory synapses, dendritic spines, dendritic NMDA- and somatic/axonal Na+ spikes that provided new insights into signal processing and computational cap
Externí odkaz:
https://doaj.org/article/17b62b6a092e44dfbfb424500128d161