High bandwidth synaptic communication and frequency tracking in human neocortex.

Autor: Guilherme Testa-Silva, Matthijs B Verhoog, Daniele Linaro, Christiaan P J de Kock, Johannes C Baayen, Rhiannon M Meredith, Chris I De Zeeuw, Michele Giugliano, Huibert D Mansvelder

Publikováno v: PLoS Biology, Vol 12, Iss 11, p e1002007 (2014)

Neuronal firing, synaptic transmission, and its plasticity form the building blocks for processing and storage of information in the brain. It is unknown whether adult human synapses are more efficient in transferring information between neurons than

Externí odkaz: https://doaj.org/article/9d69cd699b934365ad539fdbc5d4baf5

3D reconstruction and standardization of the rat vibrissal cortex for precise registration of single neuron morphology.

Autor: Robert Egger, Rajeevan T Narayanan, Moritz Helmstaedter, Christiaan P J de Kock, Marcel Oberlaender

Publikováno v: PLoS Computational Biology, Vol 8, Iss 12, p e1002837 (2012)

The three-dimensional (3D) structure of neural circuits is commonly studied by reconstructing individual or small groups of neurons in separate preparations. Investigation of structural organization principles or quantification of dendritic and axona

Externí odkaz: https://doaj.org/article/f0973d7dc1b94adb87fca2311c6f5479

Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex

Autor: Sarah Hunt, Yoni Leibner, Eline J Mertens, Natalí Barros-Zulaica, Lida Kanari, Tim S Heistek, Mahesh M Karnani, Romy Aardse, René Wilbers, Djai B Heyer, Natalia A Goriounova, Matthijs B Verhoog, Guilherme Testa-Silva, Joshua Obermayer, Tamara Versluis, Ruth Benavides-Piccione, Philip de Witt-Hamer, Sander Idema, David P Noske, Johannes C Baayen, Ed S Lein, Javier DeFelipe, Henry Markram, Huibert D Mansvelder, Felix Schürmann, Idan Segev, Christiaan P J de Kock

Publikováno v: Hunt, S, Leibner, Y, Mertens, E J, Barros-Zulaica, N, Kanari, L, Heistek, T S, Karnani, M M, Aardse, R, Wilbers, R, Heyer, D B, Goriounova, N A, Verhoog, M B, Testa-Silva, G, Obermayer, J, Versluis, T, Benavides-Piccione, R, de Witt-Hamer, P, Idema, S, Noske, D P, Baayen, J C, Lein, E S, DeFelipe, J, Markram, H, Mansvelder, H D, Schürmann, F, Segev, I & de Kock, C P J 2023, ' Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex ', Cerebral cortex (New York, N.Y. : 1991), vol. 33, no. 6, pp. 2857-2878 . https://doi.org/10.1093/cercor/bhac246
Cerebral cortex (New York, N.Y. : 1991), 33(6), 2857-2878. Oxford University Press
Hunt, S, Leibner, Y, Mertens, E J, Barros-Zulaica, N, Kanari, L, Heistek, T S, Karnani, M M, Aardse, R, Wilbers, R, Heyer, D B, Goriounova, N A, Verhoog, M B, Testa-Silva, G, Obermayer, J, Versluis, T, Benavides-Piccione, R, de Witt-Hamer, P, Idema, S, Noske, D P, Baayen, J C, Lein, E S, DeFelipe, J, Markram, H, Mansvelder, H D, Schürmann, F, Segev, I & de Kock, C P J 2023, ' Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex ', Cerebral cortex (New York, N.Y. : 1991), vol. 33, no. 6, pp. 2857-2878 . https://doi.org/10.1093/cercor/bhac246, https://doi.org/10.1093/cercor/bhac246
Cerebral cortex (New York, N.Y. : 1991), 33(6), 2857-2878. Oxford University press

Synaptic transmission constitutes the primary mode of communication between neurons. It is extensively studied in rodent but not human neocortex. We characterized synaptic transmission between pyramidal neurons in layers 2 and 3 using neurosurgically

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91045113000d5b810c2551415662a60a
https://doi.org/10.1093/cercor/bhac246

Human neocortical expansion involves glutamatergic neuron diversification

Autor: Tim S. Heistek, Thomas Braun, Natalia A. Goriounova, Michael Tieu, Lindsay Ng, Michael Hawrylycz, Kris Bickley, Anton Arkhipov, Colin Farrell, Trangthanh Pham, Alexandra Glandon, Daniel Park, Gábor Molnár, Herman Tung, Allan R. Jones, Lisa Keene, Gáspár Oláh, Thomas Chartrand, Amy Torkelson, Jae Geun Yoon, Rachel A. Dalley, Aaron Szafer, Nick Dee, Brian E. Kalmbach, Eliza Barkan, Allison Beller, Krissy Brouner, Andrew L. Ko, Alex M. Henry, Viktor Szemenyei, Julie Nyhus, Staci A. Sorensen, Samuel Dingman Lee, Norbert Mihut, Amy Bernard, Lisa Kim, Anatoly Buchin, Melissa Gorham, Lucas T. Graybuck, Lydia Potekhina, Katelyn Ward, Caitlin S. Latimer, Aaron Oldre, Gabe J. Murphy, Boaz P. Levi, Trygve E. Bakken, René Wilbers, Jonathan T. Ting, Kimberly A. Smith, Amanda Gary, Songlin Ding, Alice Mukora, Matthew Kroll, Anoop P. Patel, Wayne Wakeman, Hongkui Zeng, Nadezhda Dotson, Rusty Mann, Victoria Omstead, Leona Mezei, Desiree A. Marshall, Shea Ransford, Lydia Ng, Sara Kebede, Gábor Tamás, Jeffrey G. Ojemann, Stephanie Mok, Nathan Hansen, Christina A. Pom, Brian Lee, Jim Berg, Ramkumar Rajanbabu, John W. Phillips, Philip R. Nicovich, Matthew Mallory, Richard G. Ellenbogen, Rachel Enstrom, Luke Esposito, Tim Jarsky, Di Jon Hill, Idan Segev, Darren Bertagnolli, Agata Budzillo, Sander Idema, Daniel L. Silbergeld, Costas A. Anastassiou, Chris Hill, Michelle Maxwell, Mean Hwan Kim, Charles Cobbs, Delissa McMillen, Bosiljka Tasic, Olivia Fong, Medea McGraw, Hong Gu, Kirsten Crichton, David Reid, Kristen Hadley, Lauren Alfiler, Manuel Ferreira, Elliot R. Thomsen, Kiet Ngo, Josef Sulc, Augustin Ruiz, Katherine Baker, Zizhen Yao, Erica J. Melief, Femke Waleboer, Hanchuan Peng, Grace Williams, Rebecca D. Hodge, Kyla Berry, Katherine E. Link, David Sandman, Tsega Desta, Christine Rimorin, Jeff Goldy, Ryder P. Gwinn, Djai B. Heyer, Changkyu Lee, Jeremy A. Miller, Nathan W. Gouwens, Pál Barzó, Attila Ozsvár, Huibert D. Mansvelder, Sergey L. Gratiy, Rafael Yuste, David Feng, Jessica Trinh, Clare Gamlin, Tamara Casper, C. Dirk Keene, Susan M. Sunkin, Tom Egdorf, Philip C. De Witt Hamer, Rebecca de Frates, Peter Chong, Szabina Furdan, Patrick R. Hof, Jasmine Bomben, Christiaan P. J. de Kock, Eline J. Mertens, Ed S. Lein, Anna A. Galakhova, Florence D’Orazi, Christof Koch, Madie Hupp

Publikováno v: Berg, J, Sorensen, S A, Ting, J T, Miller, J A, Chartrand, T, Buchin, A, Bakken, T E, Budzillo, A, Dee, N, Ding, S L, Gouwens, N W, Hodge, R D, Kalmbach, B, Lee, C, Lee, B R, Alfiler, L, Baker, K, Barkan, E, Beller, A, Berry, K, Bertagnolli, D, Bickley, K, Bomben, J, Braun, T, Brouner, K, Casper, T, Chong, P, Crichton, K, Dalley, R, de Frates, R, Desta, T, Lee, S D, D’Orazi, F, Dotson, N, Egdorf, T, Enstrom, R, Farrell, C, Feng, D, Fong, O, Furdan, S, Galakhova, A A, Gamlin, C, Gary, A, Glandon, A, Goldy, J, Gorham, M, Goriounova, N A, Gratiy, S, Graybuck, L, Gu, H, Hadley, K, Hansen, N, Heistek, T S, Henry, A M, Heyer, D B, Hill, D J, Hill, C, Hupp, M, Jarsky, T, Kebede, S, Keene, L, Kim, L, Kim, M H, Kroll, M, Latimer, C, Levi, B P, Link, K E, Mallory, M, Mann, R, Marshall, D, Maxwell, M, McGraw, M, McMillen, D, Melief, E, Mertens, E J, Mezei, L, Mihut, N, Mok, S, Molnar, G, Mukora, A, Ng, L, Ngo, K, Nicovich, P R, Nyhus, J, Olah, G, Oldre, A, Omstead, V, Ozsvar, A, Park, D, Peng, H, Pham, T, Pom, C A, Potekhina, L, Rajanbabu, R, Ransford, S, Reid, D, Rimorin, C, Ruiz, A, Sandman, D, Sulc, J, Sunkin, S M, Szafer, A, Szemenyei, V, Thomsen, E R, Tieu, M, Torkelson, A, Trinh, J, Tung, H, Wakeman, W, Waleboer, F, Ward, K, Wilbers, R, Williams, G, Yao, Z, Yoon, J G, Anastassiou, C, Arkhipov, A, Barzo, P, Bernard, A, Cobbs, C, de Witt Hamer, P C, Ellenbogen, R G, Esposito, L, Ferreira, M, Gwinn, R P, Hawrylycz, M J, Hof, P R, Idema, S, Jones, A R, Keene, C D, Ko, A L, Murphy, G J, Ng, L, Ojemann, J G, Patel, A P, Phillips, J W, Silbergeld, D L, Smith, K, Tasic, B, Yuste, R, Segev, I, de Kock, C P J, Mansvelder, H D, Tamas, G, Zeng, H, Koch, C & Lein, E S 2021, ' Human neocortical expansion involves glutamatergic neuron diversification ', Nature, vol. 598, no. 7879, pp. 151-158 . https://doi.org/10.1038/s41586-021-03813-8
Nature, 598(7879), 151-158. Nature Publishing Group
Nature
Nature, Vol. 598, No. 7879
Berg, J, Sorensen, S A, Ting, J T, Miller, J A, Chartrand, T, Buchin, A, Bakken, T E, Budzillo, A, Dee, N, Ding, S-L, Gouwens, N W, Hodge, R D, Kalmbach, B, Lee, C, Lee, B R, Alfiler, L, Baker, K, Barkan, E, Beller, A, Berry, K, Bertagnolli, D, Bickley, K, Bomben, J, Braun, T, Brouner, K, Casper, T, Chong, P, Crichton, K, Dalley, R, de Frates, R, Desta, T, Lee, S D, D’Orazi, F, Dotson, N, Egdorf, T, Enstrom, R, Farrell, C, Feng, D, Fong, O, Furdan, S, Galakhova, A A, Gamlin, C, Gary, A, Glandon, A, Goldy, J, Gorham, M, Goriounova, N A, Gratiy, S, Graybuck, L, Gu, H, Hadley, K, Hansen, N, Heistek, T S, Henry, A M, Heyer, D B, Hill, D, Hill, C, Hupp, M, Jarsky, T, Kebede, S, Keene, L, Kim, L, Kim, M-H, Kroll, M, Latimer, C, Levi, B P, Link, K E, Mallory, M, Mann, R, Marshall, D, Maxwell, M, McGraw, M, McMillen, D, Melief, E, Mertens, E J, Mezei, L, Mihut, N, Mok, S, Molnar, G, Mukora, A, Ng, L, Ngo, K, Nicovich, P R, Nyhus, J, Olah, G, Oldre, A, Omstead, V, Ozsvar, A, Park, D, Peng, H, Pham, T, Pom, C A, Potekhina, L, Rajanbabu, R, Ransford, S, Reid, D, Rimorin, C, Ruiz, A, Sandman, D, Sulc, J, Sunkin, S M, Szafer, A, Szemenyei, V, Thomsen, E R, Tieu, M, Torkelson, A, Trinh, J, Tung, H, Wakeman, W, Waleboer, F, Ward, K, Wilbers, R, Williams, G, Yao, Z, Yoon, J-G, Anastassiou, C, Arkhipov, A, Barzo, P, Bernard, A, Cobbs, C, de Witt Hamer, P C, Ellenbogen, R G, Esposito, L, Ferreira, M, Gwinn, R P, Hawrylycz, M J, Hof, P R, Idema, S, Jones, A R, Keene, C D, Ko, A L, Murphy, G J, Ng, L, Ojemann, J G, Patel, A P, Phillips, J W, Silbergeld, D L, Smith, K, Tasic, B, Yuste, R, Segev, I, de Kock, C P J, Mansvelder, H D, Tamas, G, Zeng, H, Koch, C & Lein, E S 2021, ' Human neocortical expansion involves glutamatergic neuron diversification ', Nature, vol. 598, no. 7879, pp. 151-158 . https://doi.org/10.1038/s41586-021-03813-8

The neocortex is disproportionately expanded in human compared with mouse1,2, both in its total volume relative to subcortical structures and in the proportion occupied by supragranular layers composed of neurons that selectively make connections wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c41f5015a297892f279cb761e2d9f21
https://hdl.handle.net/1871.1/df908a46-b182-41b3-b732-326dddbab23b

Cellular Substrates of Functional Network Integration and Memory in Temporal Lobe Epilepsy

Autor: Martin Klein, Philip C. De Witt Hamer, Fernando A. N. Santos, René Wilbers, Jeroen J. G. Geurts, Ida A. Nissen, Djai B. Heyer, Arjan Hillebrand, Huibert D. Mansvelder, Jaap C. Reijneveld, Sophie M D D Fitzsimmons, Cornelis J. Stam, Linda Douw, Johannes C. Baayen, Natalia A. Goriounova, Elisabeth C.W. van Straaten, Hunt S, Matthijs B. Verhoog, Christiaan P. J. de Kock

Publikováno v: Cerebral cortex (New York, N.Y. : 1991), 32(11), 2424-2436. Oxford University press
Douw, L, Nissen, I A, Fitzsimmons, S M D D, Santos, F A N, Hillebrand, A, Van Straaten, E C W, Stam, C J, De Witt Hamer, P C, Baayen, J C, Klein, M, Reijneveld, J C, Heyer, D B, Verhoog, M B, Wilbers, R, Hunt, S, Mansvelder, H D, Geurts, J J G, De Kock, C P J & Goriounova, N A 2022, ' Cellular Substrates of Functional Network Integration and Memory in Temporal Lobe Epilepsy ', Cerebral cortex (New York, N.Y. : 1991), vol. 32, no. 11, pp. 2424-2436 . https://doi.org/10.1093/cercor/bhab349, https://doi.org/10.1093/cercor/bhab349
Cerebral cortex (New York, N.Y. : 1991), 32(11), 2424-2436. Oxford University Press
Douw, L, Nissen, I A, Fitzsimmons, S M D D, Santos, F A N, Hillebrand, A, van Straaten, E C W, Stam, C J, de Witt Hamer, P C, Baayen, J C, Klein, M, Reijneveld, J C, Heyer, D B, Verhoog, M B, Wilbers, R, Hunt, S, Mansvelder, H D, Geurts, J J G, de Kock, C P J & Goriounova, N A 2022, ' Cellular Substrates of Functional Network Integration and Memory in Temporal Lobe Epilepsy ', Cerebral cortex (New York, N.Y. : 1991), vol. 32, no. 11, pp. 2424-2436 . https://doi.org/10.1093/cercor/bhab349

Temporal lobe epilepsy (TLE) patients are at risk of memory deficits, which have been linked to functional network disturbances, particularly of integration of the default mode network (DMN). However, the cellular substrates of functional network int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a21f7cab97a6db4869ff28c7f3ee3eb
https://research.vu.nl/en/publications/b2e284f1-fc64-46de-be45-2eb44f65ce08