Výsledky vyhledávání - "Christiaan H. Arendzen"

Akademický článek

Generation of human induced pluripotent stem cell line EURACi006-A and its isogenic gene-corrected line EURACi006-A-1 from an arrhythmogenic cardiomyopathy patient carrying the c.1643delG PKP2 mutation

Autor: Viviana Meraviglia, Sravya Ganesh, Christiaan H. Arendzen, Christian Freund, Elena Sommariva, Alessandra Rossini, Milena Bellin

Publikováno v: Stem Cell Research, Vol 54, Iss , Pp 102426- (2021)

Arrhythmogenic Cardiomyopathy (ACM) is a rare genetic cardiac disease predominantly associated with mutations in genes of the desmosomes and characterized by arrhythmia and fibro-fatty replacement of the myocardium. We generated human induced pluripo

Externí odkaz: https://doaj.org/article/8582f8f1cc1745cea5b803e330c4f30f

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Akademický článek

Generation of human induced pluripotent stem cell line LUMCi027-A and its isogenic gene-corrected line from a patient affected by arrhythmogenic cardiomyopathy and carrying the c.2013delC PKP2 mutation

Autor: Viviana Meraviglia, Christiaan H. Arendzen, Merve Tok, Christian Freund, Angela Serena Maione, Elena Sommariva, Milena Bellin

Publikováno v: Stem Cell Research, Vol 46, Iss , Pp 101835- (2020)

Arrhythmogenic Cardiomyopathy (ACM) is a rare inherited heart muscle disease characterised by progressive fibro-fatty replacement of the ventricular myocardium leading to life-threatening arrhythmias. We generated human induced pluripotent stem cells

Externí odkaz: https://doaj.org/article/83bf51a2312947fc89fe29c2685411d1

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Akademický článek

Generation of two human induced pluripotent stem cell lines, LUMCi020-A and LUMCi021-A, from two patients with Catecholaminergic Polymorphic Ventricular Tachycardia carrying heterozygous mutations in the RYR2 gene

Autor: Viviana Meraviglia, Christiaan H. Arendzen, Christian Freund, Douwe E. Atsma, Christine L. Mummery, Milena Bellin

Publikováno v: Stem Cell Research, Vol 45, Iss , Pp - (2020)

Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is a malignant channelopathy associated with exercise- and stress-induced cardiac sudden death. The autosomal dominant form of CPVT is due to mutations in the ryanodine receptor 2 (RYR2) ge

Externí odkaz: https://doaj.org/article/04f096cec0ac49378a48a48f736017ae

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AAV-mediated gene augmentation therapy of CRB1 patient-derived retinal organoids restores the histological and transcriptional retinal phenotype

Autor: Nanda Boon, Xuefei Lu, Charlotte A. Andriessen, Ioannis Moustakas, Thilo M. Buck, Christian Freund, Christiaan H. Arendzen, Stefan Böhringer, Camiel J.F. Boon, Hailiang Mei, Jan Wijnholds

Publikováno v: Stem Cell Reports, 18, 1123-1137. Cell Press

Retinitis pigmentosa and Leber congenital amaurosis are inherited retinal dystrophies that can be caused by mutations in the Crumbs homolog 1 (CRB1) gene. CRB1 is required for organizing apical-basal polarity and adhesion between photoreceptors and M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6cc80884161b66ff80c5d37922936fc
https://hdl.handle.net/20.500.11755/dd79ec68-21cc-40df-b549-eac78660bb5f

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Generation of LUMCi041-A-2

Autor: U Chaudhari, A Ranga, Christiaan H. Arendzen, Christian Freund, O Pourquie, Harald Mikkers, Christine L. Mummery, S J Cramer

Publikováno v: Stem Cell Research, Vol 57, Iss, Pp 102592-(2021)
Stem Cell Research, 57. ELSEVIER

An induced pluripotent stem cell (iPSC) line, in which a H2B-fluorescent protein fusion is temporally expressed, is a valuable tool to track cells and study cell divisions and apoptosis. To this end we introduced a 3rd generation "all-in-one" doxycyc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d315ab315879becb2125f470c0dab47
https://hdl.handle.net/1887/3276395

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Autor: Milena Bellin, Christiaan H. Arendzen, Alessandra Rossini, Christian Freund, Sravya Ganesh, Elena Sommariva, Viviana Meraviglia

Publikováno v: Stem Cell Research
Stem Cell Research, 54. ELSEVIER
Stem Cell Research, Vol 54, Iss, Pp 102426-(2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d55c2d4cc2d75835cb5f2e849c55a1
https://hdl.handle.net/1887/3221405

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Reprogramming Urine-Derived Cells using Commercially Available Self-Replicative RNA and a Single Electroporation

Autor: Marga J. Bouma, Christine L. Mummery, Christiaan H. Arendzen, Christian Freund, Harald Mikkers

Publikováno v: Current Protocols in Stem Cell Biology

We describe a protocol for efficient generation of human‐induced pluripotent stem cells (hiPSCs) from urine‐derived cells (UDCs) obtained from adult donors using self‐replicative RNA containing the reprogramming factors OCT3/4, SOX2, KLF4, GLIS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb982b3100272b6f75a7a349fcd2914
https://pubmed.ncbi.nlm.nih.gov/32956580

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Autor: Christine L. Mummery, Milena Bellin, Christiaan H. Arendzen, Christian Freund, Douwe E. Atsma, Viviana Meraviglia

Publikováno v: Stem Cell Research, Vol 45, Iss, Pp-(2020)

Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is a malignant channelopathy associated with exercise- and stress -induced cardiac sudden death. The autosomal dominant form of CPVT is due to mutations in the ryanodine receptor 2 ( RYR2 )

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6cab7c9237c7a8e979f57d61ad0ddcd
https://pubmed.ncbi.nlm.nih.gov/32315959

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