Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Christi S. Kleoudis"'
Autor:
Susan P. Duke, Eric Lewis, Deanna D. Hill, Dimitri Bennett, Christi S. Kleoudis, Margaret Polinkovsky
Publikováno v:
Pharmaceutical Medicine. 31:113-118
Rare but serious adverse events are often reasons for the modification of drug product labelling, termination of further development and even withdrawal of a treatment from the market. Our objective was to use analytical methods to evaluate adverse e
Autor:
Amy Pierce, John Langan, Kai Hermanns, John I. Wurzelmann, Christi S. Kleoudis, Daniel Lorch, Jerry Snidow, E. Mortensen, Ben Lasko, Jan-Peter Jansen
Publikováno v:
The Journal of Pain. 12:185-193
Gastrointestinal (GI) side effects are common with opioid medication, and constipation affects ∼40% of patients. Such symptoms considerably impair patients' quality of life. Alvimopan is an orally administered, systemically available, peripherally
Autor:
Allen W. Mangel, Mark R. Heath, Christi S. Kleoudis, Teresa B. Perschy, Nicholas J. Talley, George E. Dukes, L. R. Saez, S van Zanten
Publikováno v:
Alimentary Pharmacology & Therapeutics. 15:525-537
Background: Functional dyspepsia is characterized by upper abdominal pain or discomfort. Aim: To assess the benefit of the 5-HT3-receptor antagonist alosetron in a pilot, dose-ranging, placebo-controlled, multicentre, randomized clinical trial. Metho
Autor:
Richard N. Fedorak, Christi S. Kleoudis, Kim L. Isaacs, M.Gennette Pike, Brian G. Feagan, Susan Gordon, John W.D. McDonald, Stephen B. Hanauer, Charles A. Sninsky, William J. Tremaine, Lloyd R. Sutherland, Robert H. Murdock, Dennis C. Mays, James J. Lipsky, William J. Sandborn, Douglas C. Wolf, Stephan R. Targan
Publikováno v:
Gastroenterology. 117:527-535
Background & Aims: Azathioprine is effective for Crohn's disease but acts slowly. A loading dose may decrease the time to response. Methods: A placebo-controlled study was conducted in patients with active Crohn's disease despite prednisone treatment
Autor:
E. Mortensen, Gordon Irving, Michael J. Cousins, John I. Wurzelmann, Egilius L.H. Spierings, Christi S. Kleoudis, Richard Rauck, Brian Ramjattan, Jerry Snidow, Janos Pénzes, Amy Pierce
Publikováno v:
The journal of pain. 12(2)
The balance between the pain relief provided by opioid analgesics and the side effects caused by such agents is of particular significance to patients who take opioids for the long-term relief of non-cancer pain. The spectrum of signs and symptoms af
Autor:
E. Mortensen, Jan Peter Jansen, Gordon Irving, Lynn R. Webster, Ben Lasko, John F. Peppin, Bart Morlion, Amy Pierce, Jerry Snidow, Christi S. Kleoudis, Eric G. Carter
Publikováno v:
PainReferences. 137(2)
Our objective was to investigate the efficacy and safety of alvimopan, a peripherally acting mu-opioid receptor (PAM-OR) antagonist, in subjects with non-cancer pain and opioid-induced bowel dysfunction (OBD), and to identify at least one treatment r
Autor:
Marianne T. Silver, Beverley Greenwood-Van Meerveld, Philip E. Jaffe, David L. Earnest, Christi S. Kleoudis, Sheila Rodriguez-Stanley, Malcolm Robinson, Robert H. Murdock, Lynn E. Wilson
Publikováno v:
Archives of internal medicine. 158(21)
Background: Many otherwise healthy individuals with episodic heartburn self-medicate with overthe-counter antacids. We evaluated clinical characteristics of subjects who had never been medically diagnosed as having any upper gastrointestinal tract di
Publikováno v:
Clinical therapeutics. 18(6)
As many as 89% of gastric ulcer patients experience ulcer recurrences within 1 year of successful healing with conventional antiulcer therapies. Because ranitidine is effective in the healing of gastric and duodenal ulcers and the maintenance of heal
Autor:
Bart Morlion, Amy Pierce, L. Frank, T. Bell, N. Aggarwal, Christi S. Kleoudis, Jerry Snidow, C. Wachter, A. Rentz, T. Tusker
Publikováno v:
European Journal of Pain. 10:S183c-S184
Autor:
Christi S. Kleoudis, Amy Pierce, Jerry Snidow, R. Sabatowski, L. Frank, T. Bell, M. Tark, A. Rentz
Publikováno v:
European Journal of Pain. 10:S181c-S182