Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Christi Boykin"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Classical Rho GTPases, including RhoA, Rac1, and Cdc42, are members of the Ras small GTPase superfamily and play essential roles in a variety of cellular functions. Rho GTPase signaling can be turned on and off by specific GEFs and GAPs, respectively
Externí odkaz:
https://doaj.org/article/c16c68c2904d47eab46eed448c2a3b31
Autor:
Qun Lu, Kathryn Verbanac, Emily M. Wilkerson, Laura E. Herring, Christi Boykin, Keith Pittman, George A. Howard, Yi Zhu
Chemotherapy-induced peripheral neuropathy (CIPN) is a major side effect of cancer therapy that frequently requires a reduction or cessation of treatments and negatively impacts the patient's quality of life. There is currently no effective means to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bf7126724acc6058d4ed0ad8df28a68
https://doi.org/10.1158/1541-7786.c.6541269
https://doi.org/10.1158/1541-7786.c.6541269
Autor:
Qun Lu, Kathryn Verbanac, Emily M. Wilkerson, Laura E. Herring, Christi Boykin, Keith Pittman, George A. Howard, Yi Zhu
SI Table I. General Experiment Schedule SI Table II. Weekly Experiment Schedule SI Table III. Information for primary antibodies SI Table IV. Predicted Functions of Dysregulated Proteins from Proteomic Analysis SI Figure 1. The effect of Y-27632 trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::556ce7d082e5aba234b83960958926e0
https://doi.org/10.1158/1541-7786.22516068
https://doi.org/10.1158/1541-7786.22516068
Autor:
Xin Ai, Qun Lu, Jongdee Nopparat, Mingchuan Li, Byron J. Aguilar, Jiao Zhang, Yan-Hua Chen, Yongguang Jiang, Christi Boykin, Yong Luo, Jie Du
Publikováno v:
Oncogene. 39:4358-4374
Only a small number of genes are bona fide oncogenes and tumor suppressors such as Ras, Myc, β-catenin, p53, and APC. However, targeting these cancer drivers frequently fail to demonstrate sustained cancer remission. Tumor heterogeneity and evolutio
Autor:
George Howard, Emily M. Wilkerson, Keith Pittman, Yi Zhu, Qun Lu, Kathryn M. Verbanac, Christi Boykin, Laura E. Herring
Chemotherapy-induced peripheral neuropathy (CIPN) is a major side effect of cancer therapy that frequently requires a reduction or cessation of treatments and negatively impacts the patient's quality of life. There is currently no effective means to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19678f3818242316defc704026a4e5d
https://europepmc.org/articles/PMC6774348/
https://europepmc.org/articles/PMC6774348/
Autor:
Heng Hong, Zheng D, Jongdee Nopparat, Neufer Pd, Lu Jp, Christi Boykin, Jiao Zhang, Fan Jm, Qun Lu, Chen Yh
Publikováno v:
Oncogene. 34:1542-1552
Mutations of Wnt/β-catenin signaling pathway has essential roles in development and cancer. Although β-catenin and adenomatous polyposis coli (APC) gene mutations are well established and are known to drive tumorigenesis, discoveries of mutations i
Autor:
Qun Lu, Yan-Hua Chen, Yongguang Jiang, Christi Boykin, Yong Luo, Jongdee Nopparat, Jie Du, Byron J. Aguilar, Jiao Zhang, Mingchuan Li, Xin Ai
Publikováno v:
Cancer Research. 79:2904-2904
Only a small number of genes are bona fide oncogenes and tumor suppressors such as Ras, Myc, p53 and PTEN. However, targeting these cancer drivers frequently fail to demonstrate sustained cancer remission. Tumor heterogeneity and evolution contribute
Publikováno v:
The FASEB Journal. 27
Publikováno v:
British Journal of Cancer
Background: Cucurbitacin (Cuc) and triterpene-derived natural products exhibit anti-cancer potential in addition to their conspicuous anti-bacterial and anti-inflammatory activity. Recently, inhibition of Janus kinase 2 (JAK2)/signal transducer and a
Publikováno v:
Molecular Cancer Research. 12:A35-A35
Ras activation is at the center of many signaling cascades that drive cell transformation and carcinogenesis. Strategies targeting inhibition of cellular functions of Ras can be multifaceted, from its upstream elements such as growth factors and inte