Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Christer Wernstedt"'
A new highly toxic protein isolated from the death cap Amanita phalloides is an l-amino acid oxidase
Autor:
Ulf Hellman, Taras Stasyk, Rostyslav Stoika, Christer Wernstedt, Maxim Lutsik-Kordovsky, Olga Klyuchivska, Volodymyr Antonyuk, Serhiy Souchelnytskyi
Publikováno v:
FEBS Journal. 277:1260-1269
A new highly cytotoxic protein, toxophallin, was recently isolated from the fruit body of the death cap Amanita phalloides mushroom [Stasyk et al. (2008) Studia Biologica 2, 21-32]. The physico-chemical, chemical and biological characteristics of tox
Autor:
Serhiy Souchelnytskyi, Christer Wernstedt, Rostyslav Stoika, M. Lootsik, Taras Stasyk, Ulf Hellman
Publikováno v:
Біологічні студії, Vol 2, Iss 1, Pp 21-32 (2008)
Cytotoxic protein from fruit body of the death cap Amanita phalloides mushroom, designated as toxophallin, has been isolated and its principal physico-chemical and biological properties have been characterized. This protein possesses molecular mass 5
Autor:
Taro Matsumoto, Peetra U. Magnusson, Hideo Mugishima, Skjalg Bruheim, Tone Berge, Jiong Wu, Debrabata Mukhopadhyay, Johan Dixelius, Svante Bohman, Christer Wernstedt, Charlotte Wikner, Anne Spurkland, Anna Dimberg, Lena Claesson-Welsh, Ling Wang, Jian Hua Qi
Publikováno v:
The EMBO Journal. 24:2342-2353
Vascular endothelial growth factor receptor-2 (VEGFR-2) activation by VEGF-A is essential in vasculogenesis and angiogenesis. We have generated a pan-phosphorylation site map of VEGFR-2 and identified one major tyrosine phosphorylation site in the ki
Autor:
Marika J. Karkkainen, Johan Dixelius, Kari Alitalo, Christer Wernstedt, Lena Claesson-Welsh, Taija Makinen, Maria Wirzenius
Publikováno v:
Journal of Biological Chemistry. 278:40973-40979
Vascular endothelial growth factors (VEGFs) regulate the development and growth of the blood and lymphatic vascular systems. Of the three VEGF receptors (VEGFR), VEGFR-1 and -2 are expressed on blood vessels; VEGFR-2 is found also on lymphatic vessel
Publikováno v:
Experimental Cell Research. 288:110-118
We have previously demonstrated that ligand-stimulation of c-Kit induces phosphorylation of Tyr568 and Tyr570 in the juxtamembrane region of the receptor, leading to recruitment, phosphorylation and activation of members of the Src family of tyrosine
Autor:
Gustavo Salinas, Ulf Hellman, Carmen Lorenzo, Gualberto González-Sapienza, Christer Wernstedt, Andreina Brugnini
Publikováno v:
Biochemical Journal. 369:191-198
Antigen 5 (Ag5) is a dominant secreted component of the larval stage of Echinococcus granulosus, and is highly immunogenic in human infections. Although the diagnostic value of Ag5 has been thoroughly evaluated, there has been little progress in its
Autor:
Lena Hörnsten, Ulf Hellman, Anne Osbourn, Paola Garosi, Chao Su, Ernst H. Oliw, Christer Wernstedt
Publikováno v:
Journal of Biological Chemistry. 274:28219-28224
Linoleate diol synthase is a homotetrameric ferric hemeprotein, which catalyzes dioxygenation of linoleic acid to (8R)-hydroperoxylinoleate and isomerization of the hydroperoxide to (7S,8S)-dihydroxylinoleate. Ferryl intermediates and a tyrosyl radic
Publikováno v:
Journal of Biological Chemistry. 273:23410-23418
Receptor tyrosine phosphorylation is crucial for signal transduction by creating high affinity binding sites for Src homology 2 domain-containing molecules. By expressing the intracellular domain of Flt-1/vascular endothelial growth factor receptor-1
Publikováno v:
Journal of Biological Chemistry. 273:10147-10152
Prothymosin alpha (PTA) stimulates in a dose-dependent manner the phosphorylation of a 105-kDa protein (p105) in cell extracts from different cell types. Protein sequencing and immunological analysis indicated that this protein is elongation factor 2
Publikováno v:
Lund University
Hormone-sensitive lipase (HSL) is the rate-limiting enzyme in lipolysis. Stimulation of rat adipocytes with isoproterenol results in phosphorylation of HSL and a 50-fold increase in the rate of lipolysis. In this study, we used site-directed mutagene