Zobrazeno 1 - 10
of 427
pro vyhledávání: '"Christer Larsson"'
Autor:
Kamil Demircan, Ylva Bengtsson, Thilo Samson Chillon, Johan Vallon-Christersson, Qian Sun, Christer Larsson, Martin Malmberg, Lao H. Saal, Lisa Rydén, Åke Borg, Jonas Manjer, Lutz Schomburg
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Introduction Low serum selenium and altered tumour RNA expression of certain selenoproteins are associated with a poor breast cancer prognosis. Selenoprotein expression stringently depends on selenium availability, hence circulating selenium
Externí odkaz:
https://doaj.org/article/cff4db4e410142088f7f14e1fff6b03b
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 10, Pp 4803-4821 (2022)
Smac mimetics are a group of compounds able to facilitate cell death in cancer cells. TNF-related apoptosis-inducing ligand (TRAIL) is a death receptor ligand currently explored in combination with Smac mimetics. The molecular mechanisms determining
Externí odkaz:
https://doaj.org/article/2370a8b21a8142a89caaa340af35d919
Autor:
Johan Staaf, Jari Häkkinen, Cecilia Hegardt, Lao H. Saal, Siker Kimbung, Ingrid Hedenfalk, Tonje Lien, Therese Sørlie, Bjørn Naume, Hege Russnes, Rachel Marcone, Ayyakkannu Ayyanan, Cathrin Brisken, Rebecka R. Malterling, Bengt Asking, Helena Olofsson, Henrik Lindman, Pär-Ola Bendahl, Anna Ehinger, Christer Larsson, Niklas Loman, Lisa Rydén, Martin Malmberg, Åke Borg, Johan Vallon-Christersson
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-17 (2022)
Abstract Multigene assays for molecular subtypes and biomarkers can aid management of early invasive breast cancer. Using RNA-sequencing we aimed to develop single-sample predictor (SSP) models for clinical markers, subtypes, and risk of recurrence (
Externí odkaz:
https://doaj.org/article/d2e56c524d0b4a448d746df4499518bd
Autor:
Christer Larsson, Lena Sjöberg
Publikováno v:
Nordic Journal of Studies in Educational Policy, Vol 7, Iss 1, Pp 3-15 (2021)
A key concern in international educational policy during the 21st century has been the impact of teacher professionalism on outcomes of schooling. Sweden makes for an interesting case because of the country’s initiatives to improve the quality of e
Externí odkaz:
https://doaj.org/article/65220074c80f4550906c2b3bbb0326ed
Autor:
Hasan Tükenmez, Souvik Sarkar, Saber Anoosheh, Anastasiia Kruchanova, Isabel Edström, Gregory A. Harrison, Christina L. Stallings, Fredrik Almqvist, Christer Larsson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is a major health threat listed among the top 10 causes of death worldwide. Treatment of multidrug-resistant Mtb requires use of additional second-line drugs that prolong the treatmen
Externí odkaz:
https://doaj.org/article/6c9eede13e994821b7d67d8a10ff5bf1
Autor:
Dominik Glodzik, Ana Bosch, Johan Hartman, Mattias Aine, Johan Vallon-Christersson, Christel Reuterswärd, Anna Karlsson, Shamik Mitra, Emma Niméus, Karolina Holm, Jari Häkkinen, Cecilia Hegardt, Lao H. Saal, Christer Larsson, Martin Malmberg, Lisa Rydén, Anna Ehinger, Niklas Loman, Anders Kvist, Hans Ehrencrona, Serena Nik-Zainal, Åke Borg, Johan Staaf
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
BRCA-deficient breast cancer is characterised by homologous recombination deficiency. Here, the authors show that hypermethylated BRCA1 phenotypically copies mutated BRCA1 in triple negative breast cancers.
Externí odkaz:
https://doaj.org/article/364ce59486504bf6a831a413fa23b595
Autor:
Marzieh Mohammadi, Marzieh Shafiei, Keikhosro Karimi, Amir Abdolmaleki, Jyri-Pekka Mikkola, Christer Larsson
Publikováno v:
Electronic Journal of Biotechnology, Vol 41, Iss , Pp 95-99 (2019)
Background: Pretreatment is the critically important step for the production of ethanol from lignocelluloses. In this study, hardwood birch (Betula pendula) and softwood spruce (Norway spruce) woods were pretreated with a newly synthesized morpholini
Externí odkaz:
https://doaj.org/article/8834a4da8dd4465cb9bb52791da20668
Autor:
Hani Saghir, Srinivas Veerla, Martin Malmberg, Lisa Rydén, Anna Ehinger, Lao H. Saal, Johan Vallon-Christersson, Åke Borg, Cecilia Hegardt, Christer Larsson, Alaa Haidar, Ingrid Hedenfalk, Niklas Loman, Siker Kimbung
Publikováno v:
Cancers, Vol 14, Iss 16, p 4000 (2022)
In early breast cancer, a preoperative core-needle biopsy (CNB) is vital to confirm the malignancy of suspected lesions and for assessing the expression of treatment predictive and prognostic biomarkers in the tumor to choose the optimal treatments,
Externí odkaz:
https://doaj.org/article/fecdc7ca4f294569a55903914642535e
Autor:
Rolf Søkilde, Helena Persson, Anna Ehinger, Anna Chiara Pirona, Mårten Fernö, Cecilia Hegardt, Christer Larsson, Niklas Loman, Martin Malmberg, Lisa Rydén, Lao Saal, Åke Borg, Johan Vallon-Christerson, Carlos Rovira
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Accurate classification of breast cancer using gene expression profiles has contributed to a better understanding of the biological mechanisms behind the disease and has paved the way for better prognostication and treatment predi
Externí odkaz:
https://doaj.org/article/87fb28887c884bf19a69a6e920caeda5
Autor:
Michael Bartoschek, Nikolay Oskolkov, Matteo Bocci, John Lövrot, Christer Larsson, Mikael Sommarin, Chris D. Madsen, David Lindgren, Gyula Pekar, Göran Karlsson, Markus Ringnér, Jonas Bergh, Åsa Björklund, Kristian Pietras
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Cancer-associated fibroblasts (CAFs) are an important component of the breast tumour microenvironment. Here, single-cell RNA sequencing of CAFs from a mouse model of breast cancer defines three transcriptomically distinct subpopulations with putative
Externí odkaz:
https://doaj.org/article/1659aa31381d4c7a92e2ff7e1c638daf