Blood-Based Nanoparticle-Enhanced Quaking-Induced Conversion (Nano-QuIC): Inhibitor-Resistant Detection of Seeding Activity in Patients Diagnosed with Parkinson's Disease.

Autor: Christenson PR; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota 55455, United States.; Minnesota Center for Prion Research and Outreach, University of Minnesota, St. Paul, Minnesota 55108, United States., Jeong H; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota 55455, United States., Li M; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota 55455, United States.; Minnesota Center for Prion Research and Outreach, University of Minnesota, St. Paul, Minnesota 55108, United States., Ahn H; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota 55455, United States., Schmeichel AM; Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905, United States., Misra P; Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905, United States., Li D; Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, United States., Savica R; Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905, United States., Low PA; Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905, United States., Singer W; Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905, United States., Larsen PA; Minnesota Center for Prion Research and Outreach, University of Minnesota, St. Paul, Minnesota 55108, United States.; Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, Minnesota 55108, United States., Park HY; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota 55455, United States., Oh SH; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota 55455, United States.; Minnesota Center for Prion Research and Outreach, University of Minnesota, St. Paul, Minnesota 55108, United States.

Publikováno v: Nano letters [Nano Lett] 2024 Nov 27; Vol. 24 (47), pp. 15016-15024. Date of Electronic Publication: 2024 Nov 01.

A field-deployable diagnostic assay for the visual detection of misfolded prions.

Autor: Christenson PR; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, 55455, USA.; Minnesota Center for Prion Research and Outreach (MNPRO), University of Minnesota, St. Paul, MN, 55108, USA., Li M; Minnesota Center for Prion Research and Outreach (MNPRO), University of Minnesota, St. Paul, MN, 55108, USA.; Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN, 55108, USA., Rowden G; Minnesota Center for Prion Research and Outreach (MNPRO), University of Minnesota, St. Paul, MN, 55108, USA.; Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN, 55108, USA., Schwabenlander MD; Minnesota Center for Prion Research and Outreach (MNPRO), University of Minnesota, St. Paul, MN, 55108, USA.; Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN, 55108, USA., Wolf TM; Minnesota Center for Prion Research and Outreach (MNPRO), University of Minnesota, St. Paul, MN, 55108, USA.; Department of Veterinary Population Medicine, University of Minnesota, St. Paul, MN, 55108, USA., Oh SH; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, 55455, USA. sang@umn.edu.; Minnesota Center for Prion Research and Outreach (MNPRO), University of Minnesota, St. Paul, MN, 55108, USA. sang@umn.edu., Larsen PA; Minnesota Center for Prion Research and Outreach (MNPRO), University of Minnesota, St. Paul, MN, 55108, USA. plarsen@umn.edu.; Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN, 55108, USA. plarsen@umn.edu.

Publikováno v: Scientific reports [Sci Rep] 2022 Jul 18; Vol. 12 (1), pp. 12246. Date of Electronic Publication: 2022 Jul 18.