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pro vyhledávání: '"Christensen, Lea Cecilie"'
Autor:
Christensen, Lea Cecilie, Jensen, Njal Winther, Vala, Andrea, Kamarauskaite, Jurate, Johansson, Linda, Winther, Jakob Rahr, Hofmann, Kay, Teilum, Kaare, Ellgaard, Lars
Publikováno v:
In Journal of Biological Chemistry 27 July 2012 287(31):26388-26399
Autor:
Timms, Richard T., Menzies, Sam A., Tchasovnikarova, Iva A., Christensen, Lea Cecilie, Williamson, James C., Antrobus, Robin, Dougan, Gordon, Ellgaard, Lars, Lehner, Paul J.
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Timms, R T, Menzies, S A, Tchasovnikarova, I A, Christensen, L C, Williamson, J C, Antrobus, R, Dougan, G, Ellgaard, L & Lehner, P J 2016, ' Genetic dissection of mammalian ERAD through comparative haploid and CRISPR forward genetic screens ', Nature Communications, vol. 7, 11786 . https://doi.org/10.1038/ncomms11786
Timms, R T, Menzies, S A, Tchasovnikarova, I A, Christensen, L C, Williamson, J C, Antrobus, R, Dougan, G, Ellgaard, L & Lehner, P J 2016, ' Genetic dissection of mammalian ERAD through comparative haploid and CRISPR forward genetic screens ', Nature Communications, vol. 7, 11786 . https://doi.org/10.1038/ncomms11786
The application of forward genetic screens to cultured human cells represents a powerful method to study gene function. The repurposing of the bacterial CRISPR/Cas9 system provides an effective method to disrupt gene function in mammalian cells, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::73ee85ff35cde0a75e139e765ffef7bd
https://doaj.org/article/ace455e4f2ee40ba943423c1d8c92321
https://doaj.org/article/ace455e4f2ee40ba943423c1d8c92321