Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Christelle Perrault"'
Autor:
Oren Levy, Luke J. Mortensen, Gerald Boquet, Zhixiang Tong, Christelle Perrault, Brigitte Benhamou, Jidong Zhang, Tara Stratton, Edward Han, Helia Safaee, Juliet Musabeyezu, Zijiang Yang, Marie-Christine Multon, Jonathan Rothblatt, Jean-Francois Deleuze, Charles P. Lin, Jeffrey M. Karp
Publikováno v:
Cell Reports, Vol 10, Iss 8, Pp 1261-1268 (2015)
Poor homing of systemically infused cells to disease sites may limit the success of exogenous cell-based therapy. In this study, we screened 9,000 signal-transduction modulators to identify hits that increase mesenchymal stromal cell (MSC) surface ex
Externí odkaz:
https://doaj.org/article/37d12a5599884621ad399829629b5472
Autor:
Chrystelle Girardet, Magali Mathieu, François Vallée, Jacques Le-Roux, Fangxian Sun, Laurence Fabien, Corinne Terrier, Celine Ginesty, Bruno Filoche-Romme, Florence Gruss-Leleu, Maysoun Shomali, Monsif Bouaboula, Sylvie Beccari, Pascal Desmazeau, Gilles Lebourg, Tsiala Benard, Victor Certal, Pascale Vicat, Andrew Hebert, Carlos Garcia-Echeverria, Laurent Schio, Youssef El-Ahmad, Gary Mccort, Claire Muller, Maurice Brollo, Mikhail Levit, Luc Bertin, Hong Cheng, Véronique Loyau, Valerie Steier, Fabienne Thompson, Audrey Louboutin, Fabienne Pilorge, Alexey Rak, Frank Halley, Patrick Richepin, Christelle Perrault, Pierre-Yves Abecassis, Michel Tabart, Albane Courjaud
Publikováno v:
Journal of Medicinal Chemistry. 63:512-528
More than 75% of breast cancers are estrogen receptor alpha (ERα) positive (ER+), and resistance to current hormone therapies occurs in one-third of ER+ patients. Tumor resistance is still ERα-dependent, but mutations usually confer constitutive ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb6b8e31876cd3009f301f509589bd98
https://doi.org/10.1021/acs.jmedchem.9b01293
https://doi.org/10.1021/acs.jmedchem.9b01293
Autor:
William M. Siders, Qingping Wang, Rui Kuai, Jonathan Rothblatt, Francisco J. Quintana, Juliet Musabeyezu, Yuka Milton, Heidi Kuang, Manal Alaamery, Ivan D. Mascanfroni, Martina Heinelt, Veit Rothhammer, Ali H. Alhasan, Haoyue Lan, Jessica E. Kenison, Marie-Christine Multon, Jeffrey M. Karp, Helia Safaee, Christelle Perrault, Oren Levy, Michael De Biasio, Tahir Majid, Salam Massadeh, Ada Yeste, Zhixiang Tong
Publikováno v:
J Mol Med (Berl)
Mesenchymal stem cells (MSCs) are promising candidates for the development of cell-based drug delivery systems for autoimmune inflammatory diseases, such as multiple sclerosis (MS). Here, we investigated the effect of Ro-31-8425, an ATP-competitive k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652ad45816e0721a288e4e55fa707693
https://pubmed.ncbi.nlm.nih.gov/33398468
https://pubmed.ncbi.nlm.nih.gov/33398468
Autor:
François Lanza, Paquita Nurden, Renhao Li, Frédéric Adam, Valérie Proulle, Marie-Jeanne Baas, Catherine Strassel, Christelle Perrault, Alexandre Kauskot, Pierre Mangin, Marijke Bryckaert, Sylvie Moog, Alan T. Nurden
Publikováno v:
British Journal of Haematology. 186
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fffeecbcba9b190e89a05c22c3a04f76
https://doi.org/10.1111/bjh.16068
https://doi.org/10.1111/bjh.16068
Autor:
Judith Sudhalter, Qiang Gao, Stephan Reiling, Isabelle Schreiber, Albane Courjaud, Jack Pollard, Eric Yang, Luc Bonnet, Joshua Murtie, Carlos Garcia-Echeverria, Matthieu Barrague, Fangxian Sun, Timothy He, Claudine Grepin, Monsif Bouaboula, Francisco Adrian, Bailin Zhang, Malvika Koundinya, M. Paola Castaldi, Gaetan Touyer, Bruno Lionne, Mark Munson, Richard Newcombe, Isabelle Menguy, Rosalia Arrebola, Stuart Licht, Yanjun Wang, Christopher Winter, Ronald Tomlinson, Patricia Gee, Hui Cao, Christelle Perrault, Stephanie Vougier, Aaron J. Morris, David Harper, Brigitte Benhamou, Hong Cheng, Ivan Cornella-Taracido, Daniel Simard
Publikováno v:
Cell Chemical Biology. 25:705-717.e11
Summary Activating KRAS mutations are major oncogenic drivers in multiple tumor types. Synthetic lethal screens have previously been used to identify targets critical for the survival of KRAS mutant cells, but their application to drug discovery has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab8adef1cb348b566c4cf6075801bafc
https://doi.org/10.1016/j.chembiol.2018.03.005
https://doi.org/10.1016/j.chembiol.2018.03.005
Autor:
Jidong Zhang, Oren Levy, Edward Han, Charles P. Lin, Jonathan Rothblatt, Luke J. Mortensen, Zijiang Yang, Brigitte Benhamou, Zhixiang Tong, Gerald Boquet, Juliet Musabeyezu, Jean-François Deleuze, Christelle Perrault, Jeffrey M. Karp, Tara Stratton, Marie-Christine Multon, Helia Safaee
Publikováno v:
Cell Reports, Vol 10, Iss 8, Pp 1261-1268 (2015)
Elsevier
Elsevier
Poor homing of systemically infused cells to disease sites may limit the success of exogenous cell-based therapy. In this study, we screened 9,000 signal-transduction modulators to identify hits that increase mesenchymal stromal cell (MSC) surface ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403a63e8e71b5d664378f7c05df3f2e5
https://europepmc.org/articles/PMC4361231/
https://europepmc.org/articles/PMC4361231/
Autor:
Jean-Pierre Cazenave, Sentot Santoso, Monique Freund, Josiane Dambach, Catherine Ravanat, Corinne de la Salle, Marie-Jeanne Baas, Martine Santer, Eric Rubinstein, Sylvie Moog, Christelle Perrault, François Lanza
Publikováno v:
Thrombosis and Haemostasis. 86:1238-1248
SummaryGPIb is disulfide-linked to GPIbα to form GPIb, a platelet receptor for von Willebrand factor (vWF). GPIb is in turn non covalently linked to GPIX and GPV to form the GPIb/V/IX complex. Apart from its contribution to controlling surface expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fab176053c3c98864a09d6ca2176ef99
https://doi.org/10.1055/s-0037-1616057
https://doi.org/10.1055/s-0037-1616057
Autor:
Simone Schuhler, Jean-Pierre Cazenave, and Alain van Dorsselaer, Concetta Pietropaolo, Damarys Loew, François Lanza, Martine Morales, Rosaria Arcone, Christelle Perrault, Sylvie Moog, Catherine Ravanat
Publikováno v:
Biochemistry. 39:10812-10822
Protease-activated receptors (PARs) mediate cell activation after proteolytic cleavage of their extracellular amino terminus. Thrombin selectively cleaves PAR1, PAR3, and PAR4 to induce activation of platelets and vascular cells, while PAR2 is prefer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b51bf31e41457f8b5ea7b63610e0c52
https://doi.org/10.1021/bi0003341
https://doi.org/10.1021/bi0003341
Autor:
Ghassem Rastegar-Lari, Dominique Meyer, Christelle Perrault, Paulette Legendre, José A. López, Dominique Baruch, Nadine Ajzenberg
Publikováno v:
Blood. 94:4186-4194
The conformation of the A1 domain of von Willebrand factor (vWF) is a critical determinant of its interaction with the glycoprotein (GP) Ib/V/IX complex. To better define the regulatory mechanisms of vWF A1 domain binding to the GPIb/V/IX complex, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc29f967da3bc4bd26ff6919ce50192c
https://doi.org/10.1182/blood.v94.12.4186
https://doi.org/10.1182/blood.v94.12.4186
Autor:
Médina Mekrache, Dominique Baruch, Josiane Warszawski, Christelle Perrault, Nelly Kieffer, Chantal Melchior, Damien Schoevaert
Publikováno v:
Cell Adhesion and Communication. 6:335-348
The beta3 cytoplasmic domain of the alpha v beta3 integrin is essential for intracellular signals required for cytoskeletal rearrangements. Expression of beta3Ser752Pro mutation in heterologous cells profoundly affects cell spreading and beta3 locali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fe54063e0e619178fd4f12bd00eb26
https://doi.org/10.3109/15419069809010792
https://doi.org/10.3109/15419069809010792