Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Christelle Nonne"'
Autor:
Aaron R. J. Hutton, Melissa Kirkby, Tom Van Bogaert, Peter Casteels, Christelle Nonne, Veronique De Brabandere, Ortwin Van deVyver, Lalit K. Vora, Ismaiel A. Tekko, Helen O. McCarthy, Ryan F. Donnelly
Publikováno v:
Macromolecular Materials and Engineering, Vol 309, Iss 6, Pp n/a-n/a (2024)
Abstract Nanobody molecules, derived from heavy‐chain only antibodies in camelids, represent the next generation of biotherapeutics. In addition to low immunogenicity, high stability, and potency, their single‐domain format facilitates the constr
Externí odkaz:
https://doaj.org/article/ce0e799c4203426481c78b9c8f5d0d90
Autor:
S. Blanchet‐Réthoré, Johannes Voegel, Manon Roquet, Emmanuel Vial, Audrey Bogouch, Bruno Mehul, Béatrice Bertino, Didier Zugaj, Philippe Reynier, Laurent Petit, David Piwnica, Christelle Nonne, Bastien Gamboa, V. Bourdès, Anne-Sophie Dugaret, Séverine Thibaut de Ménonville
Publikováno v:
Experimental dermatology. 27(12)
Background Rosacea is a chronic inflammatory skin disease. Characteristic vascular changes in rosacea skin include enlarged, dilated vessels of the upper dermis and blood flow increase. Brimonidine is approved for symptomatic relief of the erythema o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79fb750d75468819412da2dd4932dc1
https://pubmed.ncbi.nlm.nih.gov/30290018
https://pubmed.ncbi.nlm.nih.gov/30290018
Autor:
Bernard Ruty, Emmanuel Vial, Christelle Nonne, Douglas B. Learn, Guy Bouvier, Gérard Feraille
Publikováno v:
Photochemistry and Photobiology. 91:1479-1487
Brimonidine at 0.18%, 1% and 2% concentrations applied topically in hairless mice significantly decreased tumor burden and incidences of erythema, flaking, wrinkling and skin thickening induced by UVR. The unbiased median week to tumor ≥1 mm was in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c421abbd65ab22bd756488f3dc10184
https://doi.org/10.1111/php.12528
https://doi.org/10.1111/php.12528
Autor:
Monique Freund, Catherine Léon, Anita Eckly, Christelle Nonne, Boris Aleil, Christian Gachet, Béatrice Hechler, Jean-Pierre Cazenave, Catherine Ravanat, Josiane Weber, François Lanza, Sonia Severin, Radek C. Skoda, Ralph Tiedt, Marie Jourdain, Marie-Pierre Gratacap
Publikováno v:
Blood. 110:3183-3191
Mutations in the MYH9 gene encoding the nonmuscle myosin heavy chain IIA result in bleeding disorders characterized by a macrothrombocytopenia. To understand the role of myosin in normal platelet functions and in pathology, we generated mice with dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696c768c26b79578e5de889e548726b4
https://doi.org/10.1182/blood-2007-03-080184
https://doi.org/10.1182/blood-2007-03-080184
Autor:
Christelle Nonne, Boris Aleil, Jean-Pierre Cazenave, Christian Gachet, François Lanza, Béatrice Hechler
Publikováno v:
Therapies. 61:389-394
Resume La transposition entre modeles experimentaux et clinique en matiere d’atherothrombose sera illustree par deux exemples : d’une part, les etapes de la decouverte de medicament comme la ticlopidine et le clopidogrel, l’identification de le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f80f7cb78285a298fc6f5cc271d22883
https://doi.org/10.2515/therapie:2006067
https://doi.org/10.2515/therapie:2006067
Autor:
Kenneth A. Jacobson, Marco Cattaneo, Eun Joo Roh, Béatrice Hechler, Christelle Nonne, François Lanza, Christian Gachet, Jean-Pierre Cazenave
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 316:556-563
The platelet P2Y(1) ADP receptor is an attractive target for new antiplatelet drugs. However, because of the lack of strong and stable antagonists, only a few studies have suggested that pharmacological inhibition of the P2Y(1) receptor could efficie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5261eaa12b093a235775b54d22e99b
https://doi.org/10.1124/jpet.105.094037
https://doi.org/10.1124/jpet.105.094037
Autor:
Christian Gachet, François Lanza, Christelle Nonne, Pierre Mangin, Béatrice Hechler, Nadège Lenain, Jean-Pierre Cazenave
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 25:1293-1298
Objective— Platelet activation occurs in response to adhesion receptors for von Willebrand factor (GPIb-V-IX) and collagen (GPVI and α 2 β 1 integrin) acting upstream of phospholipase C (PLC) γ2. However, PLCβ transduces signals from Gαq prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d6bceaa62bfb33fffecdce02b46e5a
https://doi.org/10.1161/01.atv.0000163184.02484.69
https://doi.org/10.1161/01.atv.0000163184.02484.69
Autor:
Celia Quevedo, Carlos Callol, Pascual Ferrara, Françoise Bono, Denis Loyaux, Arantza Muriana, Jean-Claude Guillemot, Christelle Nonne, Jean-Pascal Herault, François Autelitano, Jean-Marc Herbert, María Cristina Diez, Donogh O'Brien, Pierre Fons, Gilles Favre, Nicolas Delcourt
The formation of new vessels in the tumor, termed angiogenesis, is essential for primary tumor growth and facilitates tumor invasion and metastasis. Hypoxia has been described as one trigger of angiogenesis. Indeed, hypoxia, which is characterized by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6654eb02e2c5919980c175ec325343f2
https://europepmc.org/articles/PMC4319010/
https://europepmc.org/articles/PMC4319010/
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 6(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e34f9fb46352b24adea353801732aba
https://pubmed.ncbi.nlm.nih.gov/17988230
https://pubmed.ncbi.nlm.nih.gov/17988230
Autor:
Christian, Gachet, Béatrice, Hechler, Christelle, Nonne, Jean-Pierre, Cazenave, François, Lanza, Boris, Aleil
Publikováno v:
Therapie. 61(5)
The transposition of experimental models to clinical situations in the atherothrombosis field will be illustrated by two examples: in one hand, the steps of the discovery of drugs such as ticlopidine and clopidogrel, the identification of their molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ee204d594a286dbbc2290b34d9e4894
https://pubmed.ncbi.nlm.nih.gov/17243267
https://pubmed.ncbi.nlm.nih.gov/17243267