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pro vyhledávání: '"Christelle Mugler"'
Autor:
Philippe Chamiot-Clerc, Christelle Mugler, Nathalie Derimay, John Thomas Feutrill, Jacques Le Roux, Frank Halley, Claudine Grepin, Caroline Leriche, David Papin, Laurent Schio
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(2)
A new series of pyrazolo[1,5-a]pyrimidines exemplified by compound 1, has been identified with moderate activity (IC50=165nM), following GSK256066 rescaffolding. Compound 1 optimization at positions 2, 3, 6 and 7 gave compound 10 with high in vitro a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d74d975afb98aee33bc583f80731c51
https://pubmed.ncbi.nlm.nih.gov/26681511
https://pubmed.ncbi.nlm.nih.gov/26681511
