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of 2
pro vyhledávání: '"Christelle Mougin"'
Targeting CEACAM5-positive solid tumors using NILK-2401, a novel CEACAM5xCD47 κλ bispecific antibody
Autor:
Anja Seckinger, Vanessa Buatois, Valéry Moine, Bruno Daubeuf, Françoise Richard, Laurence Chatel, Alizée Viandier, Nicolas Bosson, Emeline Rousset, Krzysztof Masternak, Susana Salgado-Pires, Claudia Batista, Christelle Mougin, Flora Juan-Bégeot, Yves Poitevin, Dirk Hose
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundBlocking the CD47 “don’t eat me”-signal on tumor cells with monoclonal antibodies or fusion proteins has shown limited clinical activity in hematologic malignancies and solid tumors thus far. Main side effects are associated with non-
Externí odkaz:
https://doaj.org/article/54cec0396f744440a1e37f2a5e4704e8
Autor:
Virginie Trouplin, Alexandre Hamburger, Pierre Legrain, Caroline Groizeleau, Alain Meil, Jean-Michel Gauthier, Jérôme Wojcik, Frédéric Colland, Christelle Mougin, Xavier Jacq
Publikováno v:
Genome Research. 14:1324-1332
Access to the human genome facilitates extensive functional proteomics studies. Here, we present an integrated approach combining large-scale protein interaction mapping, exploration of the interaction network, and cellular functional assays performe