Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Christelle Marminon"'
Autor:
Boglárka Papp, Marc Le Borgne, Florent Perret, Christelle Marminon, Liza Józsa, Ágota Pető, Dóra Kósa, Lajos Nagy, Sándor Kéki, Zoltán Ujhelyi, Ádám Pallér, István Budai, Ildikó Bácskay, Pálma Fehér
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2701 (2023)
The aim of this study was to formulate and characterize CK2 inhibitor-loaded alginate microbeads via the polymerization method. Different excipients were used in the formulation to improve the penetration of an active agent and to stabilize our prepa
Externí odkaz:
https://doaj.org/article/e21b1301af1e4f0b92f5cff9c9f4e2cb
Autor:
Diogo Henrique Kita, Nathalie Guragossian, Ingrid Fatima Zattoni, Vivian Rotuno Moure, Fabiane Gomes de Moraes Rego, Sabrina Lusvarghi, Thomas Moulenat, Billel Belhani, Geraldo Picheth, Sofiane Bouacida, Zouhair Bouaziz, Christelle Marminon, Malika Berredjem, Joachim Jose, Marcos Brown Gonçalves, Suresh V. Ambudkar, Glaucio Valdameri, Marc Le Borgne
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The ATP-binding cassette transporter ABCG2 mediates the efflux of several chemotherapeutic drugs, contributing to the development of multidrug resistance (MDR) in many cancers. The most promising strategy to overcome ABCG2-mediated MDR is th
Externí odkaz:
https://doaj.org/article/9507ff384b6a431cbbe3c2b6d3bf058b
Autor:
Dirk Lindenblatt, Anna Nickelsen, Violetta M. Applegate, Jennifer Hochscherf, Benedict Witulski, Zouhair Bouaziz, Christelle Marminon, Maria Bretner, Marc Le Borgne, Joachim Jose, Karsten Niefind
Publikováno v:
ACS Omega, Vol 4, Iss 3, Pp 5471-5478 (2019)
Externí odkaz:
https://doaj.org/article/6c5bcdc4d49e447faba4e5a030c89f66
Autor:
Sylwia Bloch, Bożena Nejman-Faleńczyk, Karolina Pierzynowska, Ewa Piotrowska, Alicja Węgrzyn, Christelle Marminon, Zouhair Bouaziz, Pascal Nebois, Joachim Jose, Marc Le Borgne, Luciano Saso, Grzegorz Węgrzyn
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 639-650 (2018)
Oxidative stress may be the major cause of induction of Shiga toxin-converting (Stx) prophages from chromosomes of Shiga toxin-producing Escherichia coli (STEC) in human intestine. Thus, we aimed to test a series of novel antioxidant compounds for th
Externí odkaz:
https://doaj.org/article/b2be2db2912e4af19840c620534de956
Autor:
Ehab El-Awaad, Robin Birus, Christelle Marminon, Zouhair Bouaziz, Laurens Ballentin, Dagmar Aichele, Marc Le Borgne, Joachim Jose
Publikováno v:
Pharmaceuticals, Vol 14, Iss 6, p 542 (2021)
Protein kinase CK2 is involved in regulating cellular processes, such as cell cycle, proliferation, migration, and apoptosis, making it an attractive anticancer target. We previously described a prenyloxy-substituted indeno[1,2-b]indole (5-isopropyl-
Externí odkaz:
https://doaj.org/article/ab7f35e8a13441e3bcc8e494b0f4033a
Autor:
Samer Haidar, Christelle Marminon, Dagmar Aichele, Abdelhamid Nacereddine, Wael Zeinyeh, Abdeslem Bouzina, Malika Berredjem, Laurent Ettouati, Zouhair Bouaziz, Marc Le Borgne, Joachim Jose
Publikováno v:
Molecules, Vol 25, Iss 1, p 97 (2019)
Casein kinase II (CK2) is an intensively studied enzyme, involved in different diseases, cancer in particular. Different scaffolds were used to develop inhibitors of this enzyme. Here, we report on the synthesis and biological evaluation of twenty ph
Externí odkaz:
https://doaj.org/article/cead735122584236b050184220a83eb4
Autor:
Abdeslem Bouzina, Khaoula Bechlem, Hajira Berredjem, Billel Belhani, Imène Becheker, Jacques Lebreton, Marc Le Borgne, Zouhair Bouaziz, Christelle Marminon, Malika Berredjem
Publikováno v:
Molecules, Vol 23, Iss 7, p 1682 (2018)
Several new sulfamidocarbonyloxyphosphonates were prepared in two steps, namely carbamoylation and sulfamoylation, by using chlorosulfonyl isocyanate (CSI), α-hydroxyphosphonates, and various amino derivatives and related (primary or secondary amine
Externí odkaz:
https://doaj.org/article/2954759c583843d891452d527cd7d0b2
Autor:
Abdelhamid Nacereddine, Andre Bollacke, Eszter Róka, Christelle Marminon, Zouhair Bouaziz, Ferenc Fenyvesi, Ildikó Katalin Bácskay, Joachim Jose, Florent Perret, Marc Le Borgne
Publikováno v:
Pharmaceuticals, Vol 11, Iss 1, p 10 (2018)
Since the approval of imatinib in 2001, kinase inhibitors have revolutionized cancer therapies. Inside this family of phosphotransferases, casein kinase 2 (CK2) is of great interest and numerous scaffolds have been investigated to design CK2 inhibito
Externí odkaz:
https://doaj.org/article/6a035e87689e4152973bb3407ecd5675
Autor:
Jennifer Hochscherf, Dirk Lindenblatt, Benedict Witulski, Robin Birus, Dagmar Aichele, Christelle Marminon, Zouhair Bouaziz, Marc Le Borgne, Joachim Jose, Karsten Niefind
Publikováno v:
Pharmaceuticals, Vol 10, Iss 4, p 98 (2017)
Protein kinase CK2, a member of the eukaryotic protein kinase superfamily, is associated with cancer and other human pathologies and thus an attractive drug target. The indeno[1,2-b]indole scaffold is a novel lead structure to develop ATP-competitive
Externí odkaz:
https://doaj.org/article/24ad668a92c94b90ade934644a046d63
Autor:
Samer Haidar, Zouhair Bouaziz, Christelle Marminon, Tuomo Laitinen, Antti Poso, Marc Le Borgne, Joachim Jose
Publikováno v:
Pharmaceuticals, Vol 10, Iss 1, p 8 (2017)
Protein kinase CK2, initially designated as casein kinase 2, is an ubiquitously expressed serine/threonine kinase. This enzyme, implicated in many cellular processes, is highly expressed and active in many tumor cells. A large number of compounds has
Externí odkaz:
https://doaj.org/article/301b4dbe12284dfb8a4330a98c981b1f