Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Christelle En Lin Chua"'
Autor:
Neha Dikshit, Pradeep Bist, Shannon N Fenlon, Niyas Kudukkil Pulloor, Christelle En Lin Chua, Marci A Scidmore, Jason A Carlyon, Bor Luen Tang, Swaine L Chen, Bindu Sukumaran
Publikováno v:
PLoS Pathogens, Vol 11, Iss 8, p e1005083 (2015)
Recurrent urinary tract infections (UTIs) caused by uropathogenic E. coli (UPEC) are common and morbid infections with limited therapeutic options. Previous studies have demonstrated that persistent intracellular infection of bladder epithelial cells
Externí odkaz:
https://doaj.org/article/ca5da1de1f3b4d359185dc5ce52b13c0
Autor:
Ryo Nakayama, William F. Blakely, Yu Abe, Kentaro Ariyoshi, Kosuke Kasai, Tomisato Miura, Valerie Swee Ting Goh, Christelle En Lin Chua, Zi Huai Chew, Akifumi Nakata, Yohei Fujishima, Mitsuaki A. Yoshida
Publikováno v:
International journal of radiation biology. 97(2)
In suspected radiation exposures, cytokinesis-block micronucleus (CBMN) assay is used for biodosimetry by detecting micronuclei (MN) in binucleated (BN) cells in whole blood and isolated peripheral blood mononuclear cell (PBMC) cultures. Standardized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed26bc3e5a34fa4a092a4f9d94b34309
https://pubmed.ncbi.nlm.nih.gov/33135957
https://pubmed.ncbi.nlm.nih.gov/33135957
Autor:
Christelle En Lin Chua, Bor Luen Tang
Publikováno v:
Journal of Cellular Physiology. 233:6483-6494
Rab GTPases are key regulators of eukaryotic membrane traffic, and their functions and activities are limited to particular intracellular transport steps and their membrane localization is by and large restricted. Some Rabs do participate in more tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c25fc7b66e1891906d3de19a534cb769
https://doi.org/10.1002/jcp.26503
https://doi.org/10.1002/jcp.26503
Autor:
Bor Luen Tang, Christelle En Lin Chua
Publikováno v:
Journal of molecular neuroscience : MN. 67(2)
Epigenetic influence of brain and neuronal function plays key regulatory roles in health and diseases. The microRNA miR-34a is a tumor suppressor transcript, and its loss has been prominently linked to various human cancers, including malignancies of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101324f25e6c793f585e785dd76c7e6d
https://pubmed.ncbi.nlm.nih.gov/30488149
https://pubmed.ncbi.nlm.nih.gov/30488149
Publikováno v:
FEBS Letters. 588:3186-3194
Rab31 is expressed in both GFAP- and nestin- positive fibres in regions of neurogenic potential in the adult mouse brain. To investigate the role of Rab31 in neural progenitor cells (NPCs), we cultured NPCs and found significant levels of Rab31 expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d463b2d66e610020143466b9de9c74
https://doi.org/10.1016/j.febslet.2014.06.060
https://doi.org/10.1016/j.febslet.2014.06.060
Publikováno v:
Journal of Cellular Physiology. 229:1346-1352
Many malignancies result from deletions or loss-of-function mutations in one or more tumor suppressor genes, the products of which curb unrestrained growth or induce cell death in those with dysregulated proliferative capacities. Most tumor suppresso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72b7ade9e262334009bfb171e04c84c6
https://doi.org/10.1002/jcp.24574
https://doi.org/10.1002/jcp.24574
Publikováno v:
Journal of Cellular Physiology. 227:3722-3730
Dogmatic views of how proteins and other cellular components may traffic within and between eukaryotic cells have been challenged in the past few years. Beyond the classical secretory/exocytic pathway and its established players, other pathways of ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7de129883f78a9f8e11e07187a2ffdd
https://doi.org/10.1002/jcp.24082
https://doi.org/10.1002/jcp.24082
Autor:
Christelle En Lin Chua, Bor Luen Tang
Publikováno v:
Brain Research Reviews. 67:268-281
Neuronal dysfunctions and neurodegeneration are often associated with defects in membrane transport. Synucleinopathies are a diverse group of neurodegenerative disorders that share a common pathological feature — insoluble aggregates composed large
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa20728761829f6a6710d7bfce9ae19
https://doi.org/10.1016/j.brainresrev.2011.03.002
https://doi.org/10.1016/j.brainresrev.2011.03.002
Autor:
Christelle En Lin Chua, Bor Luen Tang
Publikováno v:
Biochemical and Biophysical Research Communications. 391:6-10
Sir2/Sirt1, a mediator of longevity in several animal models, is a member of the sirtuin family of type III histone deacetylases. Its non-histone substrates include a group of regulatory molecules that modulate energy metabolism, such as peroxisome p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61134c8dd81dbe34e052f3beee2ce49e
https://doi.org/10.1016/j.bbrc.2009.11.016
https://doi.org/10.1016/j.bbrc.2009.11.016
Autor:
Bor Luen Tang, Christelle En Lin Chua
Publikováno v:
Molecular Aspects of Medicine. 29:187-200
SIRT1 is the mammalian homologue of yeast silent information regulator (Sir)-2, a member of the sirtuin family of protein deacetylases which have gained much attention as mediators of lifespan extension in several model organisms. Induction of SIRT1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3238d2eb472e1d8682430e518ca663e3
https://doi.org/10.1016/j.mam.2007.02.001
https://doi.org/10.1016/j.mam.2007.02.001