Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christelle Castell"'
Autor:
Ludovic Lacroix, Sophie F Post, Alexander Valent, Antoine E Melkane, Philippe Vielh, Coumaran Egile, Christelle Castell, Christelle Larois, Sandrine Micallef, Patrick Saulnier, Hélène Goulaouic, Anne-Marie Lefebvre, Stéphane Temam
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84319 (2014)
BACKGROUND: Identification of MET genetic alteration, mutation, or amplification in oropharyngeal squamous cell carcinoma (OPSCC) could lead to development of MET selective kinase inhibitors. The aim of this study was to assess the frequency and prog
Externí odkaz:
https://doaj.org/article/b3da9354083645a99603348b3c2733dc
Autor:
Hélène Goulaouic, Loreley Calvet, Conception Nemecek, Anne-Marie Lefebvre, Christelle Castell, Elisa Francesconi, Céline Lefranc, Sandrine Valence, Jean-Paul Nicolas, Tsiala Bénard, Fabrice Bonche, Jessica Mestadier, Véronique Do-Vale, Françoise Bégassat, Christine Delaisi, Mireille Kenigsberg, Coumaran Egile
Supplemental Tables S1-S3. Table S1 describes the antiproliferative activity of SAR125844 on a panel of cell lines and the known genetic alterations of MET and other oncogenes or tumor suppressor genes for these cell lines. Table S2 describes the ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eaf802bc9cf0f49d0972cbab5e7ce22
https://doi.org/10.1158/1535-7163.22503330
https://doi.org/10.1158/1535-7163.22503330
Autor:
Bohdan Wasylyk, Marie-Christine Multon, Laurent Debussche, Christelle Castell, Hong Zheng, Christine Wasylyk
Supplementary Figure 5 from Inhibition of the Ras-Net (Elk-3) Pathway by a Novel Pyrazole that Affects Microtubules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb971af000721e600fa919c79316a93d
https://doi.org/10.1158/0008-5472.22373939.v1
https://doi.org/10.1158/0008-5472.22373939.v1
Autor:
Bohdan Wasylyk, Marie-Christine Multon, Laurent Debussche, Christelle Castell, Hong Zheng, Christine Wasylyk
Supplementary Figure 1 from Inhibition of the Ras-Net (Elk-3) Pathway by a Novel Pyrazole that Affects Microtubules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1114cef4a27bce9ccab0943d10995512
https://doi.org/10.1158/0008-5472.22373951.v1
https://doi.org/10.1158/0008-5472.22373951.v1
Autor:
Bohdan Wasylyk, Marie-Christine Multon, Laurent Debussche, Christelle Castell, Hong Zheng, Christine Wasylyk
Net (Elk-3/SAP-2/Erp) is a transcription factor that is phosphorylated and activated by the Ras–extracellular signal-regulated kinase (Erk) signaling pathway and is involved in wound healing, angiogenesis, and tumor growth. In a cell-based screen f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47bd0f56d38704d1b03e5e6cdc248424
https://doi.org/10.1158/0008-5472.c.6497264
https://doi.org/10.1158/0008-5472.c.6497264
Autor:
Bohdan Wasylyk, Marie-Christine Multon, Laurent Debussche, Christelle Castell, Hong Zheng, Christine Wasylyk
Supplementary Figure 4 from Inhibition of the Ras-Net (Elk-3) Pathway by a Novel Pyrazole that Affects Microtubules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530faf4820b920afb9b54d61657ef190
https://doi.org/10.1158/0008-5472.22373942
https://doi.org/10.1158/0008-5472.22373942
Autor:
Bohdan Wasylyk, Marie-Christine Multon, Laurent Debussche, Christelle Castell, Hong Zheng, Christine Wasylyk
Supplementary Methods and Materials, Figure Legends 1-5, Tables 1-6 from Inhibition of the Ras-Net (Elk-3) Pathway by a Novel Pyrazole that Affects Microtubules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f422a516073fee1aaded67eced36b96
https://doi.org/10.1158/0008-5472.22373936
https://doi.org/10.1158/0008-5472.22373936
Autor:
Bohdan Wasylyk, Marie-Christine Multon, Laurent Debussche, Christelle Castell, Hong Zheng, Christine Wasylyk
Supplementary Figure 3 from Inhibition of the Ras-Net (Elk-3) Pathway by a Novel Pyrazole that Affects Microtubules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0c612192f5ff7efe72df6b4518bdcc
https://doi.org/10.1158/0008-5472.22373945.v1
https://doi.org/10.1158/0008-5472.22373945.v1
Autor:
Geoffrey I. Shapiro, Michel Dubar, Scott Kopetz, Sandrine Micallef, Jason J. Luke, Dejan Juric, Anna Spreafico, Philippe L. Bedard, Sylvaine Cartot-Cotton, Bin Wu, Keith T. Flaherty, Florent Mazuir, Brigitte Demers, Christelle Castell, Corinne Gomez, Michael A. Davies
Publikováno v:
Cancer. 124:315-324
Background Phosphoinositide 3-kinase (PI3K) β is the dominant isoform for PI3K activity in many phosphatase and tensin homolog (PTEN)-deficient tumor models. This was a first-in-human study to determine the maximum tolerated dose, safety, pharmacoki
Autor:
Jessica Mestadier, Sandrine Valence, Elisa Francesconi, Conception Nemecek, Mireille Kenigsberg, Celine Lefranc, Véronique Do-Vale, Tsiala Benard, Françoise Bégassat, Fabrice Bonche, Hélène Goulaouic, Loreley Calvet, Jean-Paul Nicolas, Coumaran Egile, Christelle Castell, Christine Delaisi, Anne-Marie Lefebvre
Publikováno v:
Molecular Cancer Therapeutics. 14:384-394
Activation of the MET/HGF pathway is common in human cancer and is thought to promote tumor initiation, metastasis, angiogenesis, and resistance to diverse therapies. We report here the pharmacologic characterization of the triazolopyridazine derivat