Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Christel Navarro"'
Autor:
Nicholas M. Durham, Ruth Franks, Christel Navarro, Kelly McGlinchey, Hong Jin, Nicola Rath, Robert W. Wilkinson, James Harper, Andrew Leinster, Rebecca Leyland, Xing Cheng, Simon J. Dovedi, Kathy Mulgrew, Lee Brown, Jon Travers, Jens-Oliver Koopmann, Shannon Burke, Danielle Carroll, Jim Eyles
Publikováno v:
Molecular Cancer Therapeutics. 20:1723-1734
A recombinant Newcastle Disease Virus (NDV), encoding either a human (NDVhuGM-CSF, MEDI5395) or murine (NDVmuGM-CSF) GM-CSF transgene, combined broad oncolytic activity with the ability to significantly modulate genes related to immune functionality
Autor:
Christel Navarro, Apostolia Maria Tsimberidou, Cecile Bougeret, Elsa Borghi, Dominique Bridon, Helene Sicard
Publikováno v:
Cancer Research. 83:4477-4477
Background: Ribosomal protein S6 kinase (S6K) is a key regulator of estrogen receptor (ER) function, and its high expression is associated with poor clinical outcomes in breast cancer (BC). Recent data have demonstrated that S6K is involved in resist
Autor:
Eric Theveneau, Ah-Lai Law, Lauren Dodgson, Roberto Mayor, Daimark Bennett, Anne Vehlow, Graham Dunn, Christel Navarro, Maria Kotini, Matthias Krause, Magdalene Michael, Upamali Perera, Cristian Bodo, Eleanor Taylor, Daniel Soong
Publikováno v:
Law, A-L, Vehlow, A, Kotini, M, Dodgson, L, Soong, D, Theveneau, E, Bodo, C, Taylor, E, Navarro, C, Perera, U, Michael, M, Dunn, G, Bennett, D, Mayor, R & Krause, M 2013, ' Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo ', Journal of Cell Biology, vol. 203, no. 4, N/A, pp. 673-689 . https://doi.org/10.1083/jcb.201304051
The Journal of Cell Biology
The Journal of Cell Biology
Lpd is an essential, evolutionary conserved regulator of the Scar/WAVE complex during cell migration in vivo.
Cell migration is essential for development, but its deregulation causes metastasis. The Scar/WAVE complex is absolutely required for l
Cell migration is essential for development, but its deregulation causes metastasis. The Scar/WAVE complex is absolutely required for l
Publikováno v:
Current Biology. 20:783-791
Summary Background Tight regulation of cell motility is essential for many physiological processes, such as formation of a functional nervous system and wound healing. Drosophila Abl negatively regulates the actin cytoskeleton effector protein Ena du
Autor:
Christine Sempéré, Jean-Paul Borg, Sylvette Chasserot-Golaz, Claire Nourry, Nicolas Vitale, Jean-Marc Strub, Alain Van Dorsselaer, Jean-Luc Dupont, Richard T. Premont, Yohanns Bellaïche, Stéphane Audebert, Patrick Lécine, Christel Navarro
Publikováno v:
Current Biology. 14(11):987-995
Drosophila Scribble is implicated in the development of normal synapse structure and epithelial tissues, but it remains unclear how it plays a role and which process it controls [1–3]. The mammalian homolog of Scribble, hScrib, has a primary struct
Autor:
James Harper, Shannon Burke, Hong Jin, Ruth Franks, Danielle Carroll, Xing Cheng, Christel Navarro, Robert J. Wilkinson, Jon Travers
Publikováno v:
Cancer Research. 77:4562-4562
Newcastle Disease Virus (NDV) is an avian paramyxovirus, which has significant oncolytic activity against mammalian cancers. It is multi-modal in its anti-tumour activity and offers a tumour selective, self-propagating therapeutic with oncolytic acti
Autor:
Cheng Xing, Weijia Wang, Qi Xu, Robert W. Wilkinson, Shannon Burke, Danielle Carroll, Hong Jin, Ruth Franks, Jon Travers, James Harper, Christel Navarro
Publikováno v:
Cancer Research. 76:2234-2234
Oncolytic viruses are live, replication-competent viruses that infect and/or replicate selectively in tumour cells leading to the destruction of the infected cell. Cell death occurs as a natural consequence of the viral life cycle and newly produced
Autor:
Rivka A. Rachel, Sylvie Marchetto, Sébastien Nola, Jean-Paul Borg, Mireille Montcouquiol, Claire Nourry, Sandrine Etienne-Manneville, Michael Sebbagh, Naël Osmani, Christel Navarro, Stéphane Audebert, Marie-Josée Santoni, Nathalie Sans
Publikováno v:
Human molecular genetics. 17(22)
Genetic studies have highlighted the key role of Scrib in the development of Metazoans. Deficiency in Scrib impairs many aspects of cell polarity and cell movement although the mechanisms involved remain unclear. In mammals, Scrib belongs to a protei
Autor:
Hong Jin, Xing Cheng, James Harper, Robert W. Wilkinson, Ruth Franks, Shannon Burke, Danielle Carroll, Jon Travers, Christel Navarro
Publikováno v:
Cancer Research. 75:5334-5334
Oncolytic viruses are live, replication-competent viruses that infect and/or replicate selectively in tumour cells leading to the destruction of the infected cell. Cell lysis occurs as a natural consequence of the viral life cycle and released virion
Publikováno v:
Oncogene. 24(41)
The E6 proteins of the high-risk Human papillomaviruses (HPV) types have a well-documented ability to target certain cellular proteins for ubiquitin-mediated degradation via the proteasome. Previous studies have shown that E6 proteins interact differ