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of 3
pro vyhledávání: '"Christel Nanz"'
Autor:
Hans Rommelspacher, Harald Borbe, Uwe Wollert, Walter E. Müller, Klaus J. Fehske, Christel Nanz
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 314:97-100
The interaction of several beta-carbolines with specific [3H]-flunitrazepam binding to benzodiazepine receptors in rat brain membranes was investigated. Out of the investigated compounds, harmane and norharmane were the most potent inhibitors of spec
Autor:
Hans Rommelspacher, Walter E. Müller, Uwe Wollert, Klaus J. Fehske, Christel Nanz, Harald Borbe
Publikováno v:
European journal of pharmacology. 70(3)
Harmane and other related β-carbolines are putative endogenous ligands of the benzodiazepine receptor. Since the compounds are potent convulsants they may have agonist activities at the benzodiazepine receptor while the benzodiazepines may be antago
Autor:
Harald Borbe, Klaus J. Fehske, Walter E. Müller, Hans Rommelspacher, Christel Nanz, Uwe Wollert
Publikováno v:
Pharmacology, biochemistry, and behavior. 14(5)
β-Carbolines have been recently proposed as candidates for the unknown endogenous ligand of the benzodiazepine receptor. Out of the β-carboline derivatives already found in the mammalian CNS, harmane is clearly the most potent inhibitor of benzodia