Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Christal Grierson"'
Autor:
Charles McSharry, Alun Barton, Colin N. A. Palmer, Jeffrey T.-J. Huang, Douglas K. Miller, Giora Feuerstein, Osama Albarbarawi, Christal Grierson, Christopher J. Weir, Petra Rauchhaus, Martina Messow, Neil C. Thomson, Jeffrey Brady, Somnath Mukhopadhyay, Rekha Chaudhuri, Nicola Stevens
Publikováno v:
Huang, J T-J, Chaudhuri, R, Albarbarawi, O, Barton, A, Grierson, C, Rauchhaus, P, Weir, C J, Messow, M, Stevens, N, McSharry, C, Feuerstein, G, Mukhopadhyay, S, Brady, J, Palmer, C N A, Miller, D & Thomson, N C 2012, ' Clinical validity of plasma and urinary desmosine as biomarkers for chronic obstructive pulmonary disease ', Thorax, vol. 67, no. 6, pp. 502-508 . https://doi.org/10.1136/thoraxjnl-2011-200279
Thorax
Thorax
Background Although an increased concentration of degraded elastin products in patients with chronic obstructive pulmonary disease (CORD) has been reported for many years, its clinical validity and utility remain uncertain due to technical difficulti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc65f2ffeaab05f5e6c035bfbbd9308
https://doi.org/10.1136/thoraxjnl-2011-200279
https://doi.org/10.1136/thoraxjnl-2011-200279
Autor:
Giora Feuerstein, Christal Grierson, Daniel Crowther, Anna M. Tommasi, Bridget Shepherd, Andrew D. Morris, Ewan R. Pearson, Lisa Logie, Antonio J. Ruiz-Alcaraz, Calum Sutherland, Jeffrey Brady, Michael K. Hansen, Christopher Schofield, H. S. Hundal
Publikováno v:
Biochemical Pharmacology. 80:1042-1049
Insulin resistance is a characteristic of type 2 diabetes and is a major independent risk factor for progression to the disease. In particular, insulin resistance associates with increased body fat and almost certainly contributes to the dramatic inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc5a21ec38fc8e65116cdcdaa7128f6
https://doi.org/10.1016/j.bcp.2010.06.011
https://doi.org/10.1016/j.bcp.2010.06.011
Autor:
Omar Hilmi, Christal Grierson, Karl Nocka, Douglas K. Miller, William MacNee, Jeffrey Brady, Neil C. Thomson, Mark Spears, C. Martina Messow, Charles McSharry, Rekha Chaudhuri, John T. Murchison, Michael Sproule, Gino Miele, Martin Connell
Publikováno v:
The European respiratory journal. 44(4)
Asthmatic smokers have poor symptom control and accelerated decline in lung function. A reduced ratio of matrix metalloproteinase (MMP)-9/tissue inhibitors of metalloproteinases (TIMPs) in nonsmokers with asthma has been implicated in airway remodell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b52aeefcd6dba89e5b3409a5f261b4
https://pubmed.ncbi.nlm.nih.gov/24993912
https://pubmed.ncbi.nlm.nih.gov/24993912
Autor:
Douglas K. Miller, Jeffrey T.-J. Huang, Timothy Jagelman, Robert Muirhead, Jeff Brady, Thomas C. Fardon, Jonathan McCormick, Sandra Steele, John H. Winter, Graham Devereux, Shona Fielding, Richard Brooker, Christal Grierson
Publikováno v:
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 13(5)
Background In cystic fibrosis (CF), cross-sectional studies have reported sputum matrix metalloproteinase (MMP)-9 to be elevated and negatively correlated with FEV 1 . This longitudinal study examined the association between MMP-9 and tissue inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564f0b09672819f1e09578cf38b9f85c
https://pubmed.ncbi.nlm.nih.gov/24525080
https://pubmed.ncbi.nlm.nih.gov/24525080
Autor:
Henning Wackerhage, Jeffrey Brady, Anna M. Tommasi, Daniel Crowther, A Joyson, A DeVries, Kenneth C. H. Fearon, Petra Rauchhaus, P Yaworsky, T Dhanani, S Alesci, Carolyn A. Greig, Aivaras Ratkevicius, Christal Grierson, I Selmer, David M. Reid, Thomas William Redpath, Fiona J. Gilbert
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences. 66(6)
Sarcopenia is the loss of muscle size and function during ageing. The aim of this study was to test whether serum concentrations of myostatin and interacting proteins (GASP-1, FLRG, and follistatin) differed between young and elderly sarcopenic men.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162531192b73e6ccf9a54ce252f041bf
https://pubmed.ncbi.nlm.nih.gov/21382886
https://pubmed.ncbi.nlm.nih.gov/21382886
Publikováno v:
Analytical biochemistry. 404(2)
The aim of this study was to combine matrix metalloproteinase-9 (MMP-9) protein (enzyme-linked immunosorbent assay [ELISA]) and MMP-9 activity (fluorescence resonance energy transfer [FRET] assay) data to generate units of specific activity in endoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10336594e31d3a3d175a9c40bb4ab0c3
https://pubmed.ncbi.nlm.nih.gov/20507826
https://pubmed.ncbi.nlm.nih.gov/20507826
Autor:
Gino Miele, Michael Sproule, Joyce Thompson, Giora Feuerstein, Jeffrey Brady, C. Martina Messow, Mark Spears, Douglas K. Miller, Charles McSharry, Martin Connell, William MacNee, Iona Donnelly, Jane Lafferty, Malcolm Shepherd, Stephen McGuinness, Christal Grierson, Karl Nocka, Christopher J. Weir, Neil C. Thomson, Dan Crowther, M Brannigan, John T. Murchison, Lisa Jolly, Rekha Chaudhuri
Publikováno v:
Journal of Allergy and Clinical Immunology. 129:655-663.e8
Background Matrix metalloproteinase (MMP)-12 has been implicated in the pathogenesis of both chronic obstructive pulmonary disease (COPD) and asthma. The influence of disease severity on sputum MMP-12 concentrations and activity is not known. Objecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b25e4ca4c8f159a488f15799a9ca550
https://doi.org/10.1016/j.jaci.2011.12.996
https://doi.org/10.1016/j.jaci.2011.12.996
Autor:
Margaret Fleming, Doug Miller, Jeff Brady, Christal Grierson, Joseph P. Sypek, Peter LaPan, Bin Fu
Publikováno v:
BMC Pulmonary Medicine
BMC Pulmonary Medicine, Vol 10, Iss 1, p 40 (2010)
BMC Pulmonary Medicine, Vol 10, Iss 1, p 40 (2010)
Background Proteolysis of matrix components, in particular elastin, is a major contributing factor to the development of lung diseases such as emphysema and chronic obstructive pulmonary disease (COPD). MMP-12 (macrophage elastase) is a protease know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ade63647260c0fe1bc29f96f1ea20572
http://europepmc.org/articles/PMC2921351
http://europepmc.org/articles/PMC2921351
Autor:
Michael Sproule, Christal Grierson, John T. Murchison, Karl Nocka, William MacNee, Rekha Chaudhuri, C. Martina Messow, Neil C. Thomson, Omar Hilmi, Charles McSharry, Douglas K. Miller, Gino Miele, Martin Connell, Jeffrey Brady, Mark Spears
Publikováno v:
Translational Respiratory Medicine
Chaudhuri, R, Mcsharry, C, Spears, M, Brady, J, Grierson, C, Messow, C, Miele, G, Nocka, K, Macnee, W, Connell, M, Murchison, J T, Sproule, M, Hilmi, O, Miller, D K & Thomson, N C 2013, ' Sputum matrix metalloproteinase-9 is associated with the degree of emphysema on computed tomography in COPD ' vol. 1, no. 1, pp. 11 . DOI: 10.1186/2213-0802-1-11
Chaudhuri, R, Mcsharry, C, Spears, M, Brady, J, Grierson, C, Messow, C, Miele, G, Nocka, K, Macnee, W, Connell, M, Murchison, J T, Sproule, M, Hilmi, O, Miller, D K & Thomson, N C 2013, ' Sputum matrix metalloproteinase-9 is associated with the degree of emphysema on computed tomography in COPD ' vol. 1, no. 1, pp. 11 . DOI: 10.1186/2213-0802-1-11
Background Matrix-metalloproteinase (MMP)-9 has been implicated in the pathogenesis of COPD, although its link to disease severity is unclear. The purpose of the study was to examine the relationship between disease severity assessed by lung function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c12ff9e9561dd2a8dc8b6ad97c1c7d5