Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Christal G. Young"'
Autor:
Jane E. Strasser, Michael G. Meador, Chin-Fun Chu, Christal G. Young, Nigel Bourne, Gregg N. Milligan
Publikováno v:
Journal of Reproductive Immunology. 78:58-67
The ability of antibody (Ab) to modulate HSV pathogenesis is well recognized but the mechanisms by which HSV-specific IgG antibodies protect against genital HSV-2 disease are not well understood. The requirement for Ab interactions with Fcgamma recep
Publikováno v:
Biology of Reproduction. 71:1638-1645
Vaginally applied antimicrobial compounds (microbicides) are being developed as an alternative method for preventing the spread of sexually transmitted diseases. In addition to identifying compounds effective against a spectrum of sexually transmitte
Publikováno v:
Journal of Reproductive Immunology. 61:115-127
Resolution of a HSV-2 infection of the female genital tract has been shown to be T-cell dependent. The T-cell populations and mechanisms involved in clearance of virus from the genital epithelium were examined in this study. T lymphocytes expressing
Autor:
Zhao Yong Hu, Harry Ischiropoulos, Dale Uyeminami, Scott W. Ballinger, Kent E. Pinkerton, Christal G. Young, Cynthia A. Knight-Lozano, David L. Burow
Publikováno v:
Circulation. 105:849-854
Background — A shared feature among cardiovascular disease risk factors is increased oxidative stress. Because mitochondria are susceptible to damage mediated by oxidative stress, we hypothesized that risk factors (secondhand smoke and hypercholest
Autor:
Gregg N. Milligan, Michael G. Meador, Chin-Fun Chu, Talitha L. Martin, Nigel Bourne, Christal G. Young
Publikováno v:
Journal of virology. 79(17)
The tissue sites of long-term herpes simplex virus type 2 (HSV-2)-specific antibody production in mice and guinea pigs were identified. In addition to secondary lymphoid tissue and bone marrow, HSV-specific plasma cells were detected in spinal cords
Publikováno v:
Journal of reproductive immunology. 66(2)
Ideally, a vaginally-applied microbicide would be effective against a broad range of pathogens but would have minimal effects on the female genital tract. The aim of this study was to determine if representative candidate detergent-type and sulfated/
Publikováno v:
Biology of reproduction. 71(5)
Vaginally applied antimicrobial compounds (microbicides) are being developed as an alternative method for preventing the spread of sexually transmitted diseases. In addition to identifying compounds effective against a spectrum of sexually transmitte
Publikováno v:
Virology. 318(2)
Intravaginal (ivag) or intranasal (i.n.) immunization of C57BL/6J (B6) mice with a thymidine kinase-deficient strain (tk-) of herpes simplex virus type 2 (HSV-2) resulted in comparable protection of the genital epithelium and sensory ganglia against
Autor:
Bennett Van Houten, David L. Burow, Chang Ning Yan, Cam Patterson, Carol A. Ballinger, Scott W. Ballinger, Christal G. Young, F. Michael Yakes, Richard Doan, Bruce A. Freeman, Marschall S. Runge
Publikováno v:
Circulation research. 86(9)
Abstract —The mechanisms by which reactive species (RS) participate in the development of atherosclerosis remain incompletely understood. The present study was designed to test the hypothesis that RS produced in the vascular environment cause mitoc