Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christabelle S M Goh"'
Publikováno v:
Differentiation. 98:14-24
Xenograft models to study skin physiology have been popular for scientific use since the 1970s, with various developments and improvements to the techniques over the decades. Xenograft models are particularly useful and sought after due to the lack o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130e07e040c38a3138aa160487108562
https://doi.org/10.1016/j.diff.2017.09.004
https://doi.org/10.1016/j.diff.2017.09.004
Autor:
Hansjörg Baurecht, Young-Ae Lee, John Burn, W.H. Irwin McLean, Marek Gierlinski, Heather J. Cordell, Sean P. Saunders, Geoffrey J. Barton, SJ Meggitt, Roger Tavendale, Christabelle S M Goh, Vishnu Madhok, Padraic G. Fallon, Allan Balmain, Colin N. A. Palmer, Christian Cole, Sara J. Brown, Alan R. Prescott, Somnath Mukhopadhyay, Alan D. Irvine, Catherine H. Smith, Rebecca M. Porter, Frank Sullivan, Nick J. Reynolds, Linda E. Campbell, Georg Schneider, Christian Gieger, Stephan Weidinger, Aileen Sandilands, M Allen, Caroline L Relton, Jonathan Barker, Michael Kabesch, Stephen W Turner
Publikováno v:
The Journal of allergy and clinical immunology, vol 132, iss 5
J. Allergy Clin. Immunol. 132, 1121-1129 (2013)
The Journal of Allergy and Clinical Immunology
J. Allergy Clin. Immunol. 132, 1121-1129 (2013)
The Journal of Allergy and Clinical Immunology
BACKGROUND: Atopic dermatitis (AD) is a major inflammatory condition of the skin caused by inherited skin barrier deficiency,with mutations in the filaggrin gene predisposing to development of AD. Support for barrier deficiency initiating AD came fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3a4ae4fd7973bb69cb5dd627dee277
Autor:
Reuven Bergman, Ofer Isakov, Akemi Ishida-Yamamoto, Christabelle S M Goh, Andrea Gat, Neil J. Wilson, Michael A. Simpson, Ofer Sarig, Liat Samuelov, Jennifer L. Koetsier, Noam Shomron, Eli Sprecher, W.H. Irwin McLean, Mia Horowitz, Alan D. Irvine, Robert M. Harmon, Sarit Peleg, Debora Rapaport, Kathleen J. Green, John A. McGrath, O. Eytan, Frances J.D. Smith, Ronen Spiegel, Elizabeth Pohler, Shamir Geller, Ilan Goldberg
Publikováno v:
Nature Genetics. 45:1244-1248
The relative contribution of immunological dysregulation and impaired epithelial barrier function to allergic diseases is still a matter of debate. Here we describe a new syndrome featuring severe dermatitis, multiple allergies and metabolic wasting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e489c9caa3ddf7e8d9f4e5bf591014
https://doi.org/10.1038/ng.2739
https://doi.org/10.1038/ng.2739
Autor:
Aileen Sandilands, Elizabeth Pohler, Fatema Thawer-Esmail, Linda E. Campbell, Akiharu Kubo, Jun Kudoh, Colin S. Munro, Alan D. Irvine, W.H. Irwin McLean, Sara J. Brown, Neil J. Wilson, Christabelle S M Goh, Masayuki Amagai, Takeshi Matsui, Kenichi Miyamoto
Publikováno v:
The Journal of investigative dermatology
To the Editor A key event during epidermal differentiation is the proteolytic breakdown of profilaggrin into “free” filaggrin monomers. A recent study has shown that the skin specific retroviral-like aspartic protease (SASPase) plays a key role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de54daaff150df2bfef576c673c26622
https://doi.org/10.1038/jid.2011.479
https://doi.org/10.1038/jid.2011.479
Autor:
Hiroshi Shimizu, Toshifumi Nomura, Neil J. Wilson, Moez Gribaa, Sébastien Teissier, Alan D. Irvine, Alan Evans, W.H. Irwin McLean, Sara J. Brown, Mohamed Denguezli, Ali Saad, Mohammad Shboul, Ons Mamaï, Christian Cole, Geoffrey J. Barton, M. Zamiri, John A. McGrath, Colin S. Munro, Jennifer Hirst, Patricia J.C. Dopping-Hepenstal, Frances J.D. Smith, Lobna Boussofara, Mitsuhiro Suehiro, Elizabeth Pohler, David Goudie, Benvon Moran, Bruno Reversade, H. M. Horn, Aileen Sandilands, Christabelle S M Goh, Izumi Konohana, Masashi Akiyama
Publikováno v:
Nature genetics
Nature genetics, 44(11), 1272-1276. Nature Publishing Group
Nature genetics, 44(11), 1272-1276. Nature Publishing Group
Palmoplantar keratodermas (PPKs) are a group of disorders that are diagnostically and therapeutically problematic in dermatogenetics(1-3). Punctate PPKs are characterized by circumscribed hyperkeratotic lesions on the palms and soles with considerabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a0e0e3b892675d1146fd9e86bd1469
https://doi.org/10.1038/ng.2444
https://doi.org/10.1038/ng.2444
Autor:
Huijia Chen, Linda E. Campbell, Mark B Y Tang, H. P. Van Bever, Sara J. Brown, Rebecca L. Haines, A. Balakrishnan, Yoke Chin Giam, Karin Kroboth, Christabelle S M Goh, Heather J. Cordell, Whi McLean, Aileen Sandilands, Alan D. Irvine, Ellen Birgitte Lane, D L M Goh, John E.A. Common
Publikováno v:
British Journal of Dermatology. 165:106-114
Summary Background Null mutations in the filaggrin gene (FLG) cause ichthyosis vulgaris (IV) and predispose to atopic dermatitis (AD). Cohort studies in Europe and Japan have reported an FLG mutation carrier frequency of between 14% and 56%, but the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e48e85300d568163fe9fcd3ad3e046f
https://doi.org/10.1111/j.1365-2133.2011.10331.x
https://doi.org/10.1111/j.1365-2133.2011.10331.x
Autor:
Anita Balakrishnan, Christabelle S M Goh, Audrey W.H. Tan, Rebecca L. Haines, John E.A. Common, Mark B.Y. Tang, E. Birgitte Lane, Huijia Chen, H.H. Tan, Sara J. Brown, Colin S. Munro
Publikováno v:
Journal of Investigative Dermatology. 131(6):1378-1380
TO THE EDITOR Acne vulgaris is a very common skin disorder, affecting to some degree 88–94% of Singaporean adolescents (Tan et al., 2007; Yosipovitch et al., 2007). Genetic predisposition is a significant risk factor, as illustrated by familial and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7faac3a8ea8736429e4b1567f0ac8d9f