Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Christa S, Zerbe"'
Autor:
Ehren Dancy, Pamela Stratton, Dominique C. Pichard, Beatriz E. Marciano, Edward W. Cowen, Alison A. McBride, Koenraad Van Doorslaer, Melissa A. Merideth, Noemi Salmeri, Marybeth S. Hughes, Theo Heller, Mark Parta, Dennis D. Hickstein, Heidi H. Kong, Steven M. Holland, Christa S. Zerbe
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectivePatients with pathogenic variants in the GATA Binding Protein 2 (GATA2), a hematopoietic transcription factor, are at risk for human papillomavirus-related (HPV) anogenital cancer at younger than expected ages. A female cohort with GATA2 hap
Externí odkaz:
https://doaj.org/article/d6962edf636b4e08a6feb288037c400d
Autor:
Yair Mina, Ahnika Kline, Maura Manion, Dima A. Hammoud, Tianxia Wu, Julie Hogan, Irini Sereti, Bryan R. Smith, Christa S. Zerbe, Steven M. Holland, Avindra Nath
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionNontuberculous mycobacteria (NTM) mediated infections are important to consider in cases with neuroinflammatory presentations. We aimed to characterize cases of NTM with neurological manifestations at the National Institutes of Health (NI
Externí odkaz:
https://doaj.org/article/79ef037e09b04c8d920057c2c268713f
Autor:
Hélène Salvator, Aristine Cheng, Lindsey B. Rosen, Peter R. Williamson, John E. Bennett, Anuj. Kashyap, Li Ding, Kyung J. Kwon-Chung, Ho Namkoong, Christa S. Zerbe, Steven M. Holland
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background Anti GM-CSF autoantibodies (aAb) have been related to acquired pulmonary alveolar proteinosis (PAP) and described in cases of severe infections such as cryptococcosis and nocardiosis in previously healthy subjects. Whether there a
Externí odkaz:
https://doaj.org/article/19dbb33ec6054005bbc2d6f1687174c6
Autor:
Breanna J. Beers, Morgan N. Similuk, Rajarshi Ghosh, Bryce A. Seifert, Leila Jamal, Michael Kamen, Michael R. Setzer, Colleen Jodarski, Rylee Duncan, Devin Hunt, Madison Mixer, Wenjia Cao, Weimin Bi, Daniel Veltri, Eric Karlins, Lingwen Zhang, Zhiwen Li, Andrew J. Oler, Kathleen Jevtich, Yunting Yu, Haley Hullfish, Bibiana Bielekova, Pamela Frischmeyer-Guerrerio, An Dang Do, Laryssa A. Huryn, Kenneth N. Olivier, Helen C. Su, Jonathan J. Lyons, Christa S. Zerbe, V. Koneti Rao, Michael D. Keller, Alexandra F. Freeman, Steven M. Holland, Luis M. Franco, Magdalena A. Walkiewicz, Jia Yan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
PurposeThough copy number variants (CNVs) have been suggested to play a significant role in inborn errors of immunity (IEI), the precise nature of this role remains largely unexplored. We sought to determine the diagnostic contribution of CNVs using
Externí odkaz:
https://doaj.org/article/5a9a5d2c1d2843bb9d22ca82e9ec744f
Autor:
Rebecca A. Drummond, Jigar V. Desai, Amy P. Hsu, Vasileios Oikonomou, Donald C. Vinh, Joshua A. Acklin, Michael S. Abers, Magdalena A. Walkiewicz, Sarah L. Anzick, Muthulekha Swamydas, Simon Vautier, Mukil Natarajan, Andrew J. Oler, Daisuke Yamanaka, Katrin D. Mayer-Barber, Yoichiro Iwakura, David Bianchi, Brian Driscoll, Ken Hauck, Ahnika Kline, Nicholas S.P. Viall, Christa S. Zerbe, Elise M.N. Ferré, Monica M. Schmitt, Tom DiMaggio, Stefania Pittaluga, John A. Butman, Adrian M. Zelazny, Yvonne R. Shea, Cesar A. Arias, Cameron Ashbaugh, Maryam Mahmood, Zelalem Temesgen, Alexander G. Theofiles, Masayuki Nigo, Varsha Moudgal, Karen C. Bloch, Sean G. Kelly, M. Suzanne Whitworth, Ganesh Rao, Cindy J. Whitener, Neema Mafi, Juan Gea-Banacloche, Lawrence C. Kenyon, William R. Miller, Katia Boggian, Andrea Gilbert, Matthew Sincock, Alexandra F. Freeman, John E. Bennett, Rodrigo Hasbun, Constantinos M. Mikelis, Kyung J. Kwon-Chung, Yasmine Belkaid, Gordon D. Brown, Jean K. Lim, Douglas B. Kuhns, Steven M. Holland, Michail S. Lionakis
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 22 (2022)
Subcutaneous phaeohyphomycosis typically affects immunocompetent individuals following traumatic inoculation. Severe or disseminated infection can occur in CARD9 deficiency or after transplantation, but the mechanisms protecting against phaeohyphomyc
Externí odkaz:
https://doaj.org/article/71c653dd808145c48e7e7ce5ab2b01ae
Autor:
Amy P. Hsu, Agnieszka Korzeniowska, Cynthia C. Aguilar, Jingwen Gu, Eric Karlins, Andrew J. Oler, Gang Chen, Glennys V. Reynoso, Joie Davis, Alexandria Chaput, Tao Peng, Ling Sun, Justin B. Lack, Derek J. Bays, Ethan R. Stewart, Sarah E. Waldman, Daniel A. Powell, Fariba M. Donovan, Jigar V. Desai, Nima Pouladi, Debra A. Long Priel, Daisuke Yamanaka, Sergio D. Rosenzweig, Julie E. Niemela, Jennifer Stoddard, Alexandra F. Freeman, Christa S. Zerbe, Douglas B. Kuhns, Yves A. Lussier, Kenneth N. Olivier, Richard C. Boucher, Heather D. Hickman, Jeffrey Frelinger, Joshua Fierer, Lisa F. Shubitz, Thomas L. Leto, George R. Thompson III, John N. Galgiani, Michail S. Lionakis, Steven M. Holland
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
Disseminated coccidioidomycosis (DCM) is caused by Coccidioides, pathogenic fungi endemic to the southwestern United States and Mexico. Illness occurs in approximately 30% of those infected, less than 1% of whom develop disseminated disease. To addre
Externí odkaz:
https://doaj.org/article/cebc40ab082748549ea91e23e65f0242
Autor:
Alex Hopke, Allison Scherer, Samantha Kreuzburg, Michael S. Abers, Christa S. Zerbe, Mary C. Dinauer, Michael K. Mansour, Daniel Irimia
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Neutrophils employ several mechanisms to control the growth of fungi, including enzymes, reactive oxygen species, extracellular traps, and formation of “swarms”. Here, Hopke et al. study how the different mechanisms work together, using an in vit
Externí odkaz:
https://doaj.org/article/5f5b9de83fd34c48ac2c106384e5e005
Autor:
Alexander H. Yang, Brigit Sullivan, Christa S. Zerbe, Suk See De Ravin, Andrew M. Blakely, Martha M. Quezado, Beatriz E. Marciano, Jamie Marko, Alexander Ling, David E. Kleiner, John I. Gallin, Harry L. Malech, Steven M. Holland, Theo Heller
Publikováno v:
The Journal of Allergy and Clinical Immunology: In Practice. 11:1401-1416
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c593a85fe3866bae965a8c4f09523c1
https://doi.org/10.1016/j.jaip.2022.12.039
https://doi.org/10.1016/j.jaip.2022.12.039
Autor:
Joseph M. Rocco, Lindsey B. Rosen, Gloria H. Hong, Jennifer Treat, Samantha Kreuzburg, Steven M. Holland, Christa S. Zerbe
Publikováno v:
Journal of Translational Autoimmunity, Vol 4, Iss , Pp 100102- (2021)
Interferon-γ autoantibodies increase the risk of disseminated nontuberculous mycobacterial infections. Addition of rituximab to antibiotics accelerates and improves outcomes, but refractory infections can occur due to persistent production of autoan
Externí odkaz:
https://doaj.org/article/8e9cd10359e84c328ca92f70823d95f4
Autor:
Ofer Zimmerman, Peter Olbrich, Alexandra F. Freeman, Lindsey B. Rosen, Gulbu Uzel, Christa S. Zerbe, Sergio D. Rosenzweig, Hye Sun Kuehn, Kevin L. Holmes, David Stephany, Li Ding, Elizabeth P. Sampaio, Amy P. Hsu, Steven M. Holland
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Signal transducer and activator of transcription (STAT1)1 gain of function (GOF) pathogenic variants have been associated with increased levels of phosphorylated STAT1 and STAT1-dependent cellular responses. Delayed dephosphorylation was proposed as
Externí odkaz:
https://doaj.org/article/7451b57e604e4c9b9b380c85439ac3fb