Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christa L. Gray"'
Autor:
Christopher E. Henderson, Daniel Eric Sherman, Frederic J. de Sauvage, Alain Garces, Richard Vejsada, Robert D. Klein, Malú G. Tansey, Kelli S. Simburger, Kristian Todd Poulsen, Patricia A. Lampe, Robert O. Heuckeroth, Christa L. Gray, Eugene M. Johnson, Paul T. Kotzbauer, Judith P. Golden, Ann C. Kato, Li-Chong Wang, Melanie L. Leitner, Jeffrey Milbrandt, Merry Nishimura, Barbara Moffat, Heidi S. Phillips, Richard Vandlen, Robert H. Baloh, Timothy J. Fahrner, Jamie A. Davies, Mary Hynes
Publikováno v:
Neuron. 20(2):245-253
A novel neurotrophic factor named Persephin that is approximately 40% identical to glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) has been identified using degenerate PCR. Persephin, like GDNF and NTN, promotes the survival of
Autor:
James P. Sheridan, Kevin P. Baker, Scot A. Marsters, Audrey Goddard, Paul J. Godowski, Daryl T. Baldwin, Austin L. Gurney, Christa L. Gray, William I. Wood, Maya Skubatch, Robert M. Pitti, Avi Ashkenazi, Lakshmi Ramakrishnan
Publikováno v:
Science. 277:818-821
TRAIL (also called Apo2L) belongs to the tumor necrosis factor family, activates rapid apoptosis in tumor cells, and binds to the death-signaling receptor DR4. Two additional TRAIL receptors were identified. The receptor designated death receptor 5 (
Publikováno v:
Journal of Biological Chemistry. 272:14029-14032
The mammalian tumor necrosis factor receptor (TNFR) family consists of 10 cell-surface proteins that regulate development and homeostasis of the immune system. Based on an expressed sequence tag, we have cloned a cDNA encoding a novel member of the h
Autor:
Mark W. Moore, Donna M. Stone, Mark Armanini, Franz Hefti, James J.S. Treanor, Alun M. Davies, Richard A. Pollock, Laurie J. Goodman, Christopher E. Henderson, Masahide Takahashi, Arnon Rosenthal, Kristian Todd Poulsen, Naoya Asai, Christa L. Gray, Heidi S. Phillips, Richard Vandlen, Frederic J. de Sauvage, Audry Goddard, Claus D. Beck, Anna Buj-Bello
Publikováno v:
ResearcherID
Nature
Nature, 1996, 382 (6586), pp.80-83. ⟨10.1038/382080A0⟩
Nature, Nature Publishing Group, 1996, 382 (6586), pp.80-83. ⟨10.1038/382080A0⟩
Nature
Nature, 1996, 382 (6586), pp.80-83. ⟨10.1038/382080A0⟩
Nature, Nature Publishing Group, 1996, 382 (6586), pp.80-83. ⟨10.1038/382080A0⟩
Glial-cell-line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons, and is essential for the development of kidneys and the enteric nervous system. Despite the potential clinical and physiological import
Autor:
Audrey Goddard, Kenneth D. Bauer, Christopher J. Donahue, Christa L. Gray, Robert M. Pitti, James P. Sheridan, Scot A. Marsters, Avi Ashkenazi
Publikováno v:
Current Biology. (12):1669-1676
Background Two receptors that contain the so-called ‘death domain' have been described to date: tumor necrosis factor receptor 1 (TNFR1) and Fas/Apo-1 (CD95); both belong to the TNFR gene family. The death domain of TNFR1 mediates the activation of