Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Christa L Borgman"'
Autor:
Roland T Ullrich, Thomas Zander, Bernd Neumaier, Mirjam Koker, Takeshi Shimamura, Yannic Waerzeggers, Christa L Borgman, Samir Tawadros, Hongfeng Li, Martin L Sos, Heiko Backes, Geoffrey I Shapiro, Jürgen Wolf, Andreas H Jacobs, Roman K Thomas, Alexandra Winkeler
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3908 (2008)
BACKGROUND: Inhibition of the epidermal growth factor receptor (EGFR) has shown clinical success in patients with advanced non-small cell lung cancer (NSCLC). Somatic mutations of EGFR were found in lung adenocarcinoma that lead to exquisite dependen
Externí odkaz:
https://doaj.org/article/8f3796ed7f8842debdaa3df812da553c
Autor:
Kwok-Kin Wong, Jeffrey E. Settleman, Lucian R. Chirieac, Robert F. Padera, Kathleyn A. Brandstetter, Ultan McDermott, Christa L. Borgman, Danan Li, Kate L. McNamara, Leena Gandhi
Supplementary Table 1 from Sunitinib Prolongs Survival in Genetically Engineered Mouse Models of Multistep Lung Carcinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2044f0bdac7d342dbb28e1b4b1ac28a3
https://doi.org/10.1158/1940-6207.22523724
https://doi.org/10.1158/1940-6207.22523724
Autor:
Kwok-Kin Wong, Jeffrey E. Settleman, Lucian R. Chirieac, Robert F. Padera, Kathleyn A. Brandstetter, Ultan McDermott, Christa L. Borgman, Danan Li, Kate L. McNamara, Leena Gandhi
Perspective on this Article from Sunitinib Prolongs Survival in Genetically Engineered Mouse Models of Multistep Lung Carcinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ac56b2feff32f36c2fc1be54489dad
https://doi.org/10.1158/1940-6207.22523727.v1
https://doi.org/10.1158/1940-6207.22523727.v1
Autor:
Geoffrey I. Shapiro, Kwok-Kin Wong, James Barsoum, Weiwen Ying, Matthew Meyerson, John-Paul Jimenez, Christa L. Borgman, Christopher D. Carey, Papiya Sinha, Yu-Chen Li, Julian Carretero, Danan Li, Liang Chen, Takayo Inoue, Scott J. Rodig, Jim Sang, Kevin P. Foley, Samanthi A. Perera, Takeshi Shimamura
PDF file, 560K, Comparison of ganetespib and 17-AAG efficacy in NSCLC cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a555c0f4d08af5efbb19260faf90ba18
https://doi.org/10.1158/1078-0432.22443386.v1
https://doi.org/10.1158/1078-0432.22443386.v1
Autor:
Geoffrey I. Shapiro, Kwok-Kin Wong, James Barsoum, Weiwen Ying, Matthew Meyerson, John-Paul Jimenez, Christa L. Borgman, Christopher D. Carey, Papiya Sinha, Yu-Chen Li, Julian Carretero, Danan Li, Liang Chen, Takayo Inoue, Scott J. Rodig, Jim Sang, Kevin P. Foley, Samanthi A. Perera, Takeshi Shimamura
Purpose: We describe the anticancer activity of ganetespib, a novel non-geldanamycin heat shock protein 90 (HSP90) inhibitor, in non-small cell lung cancer (NSCLC) models.Experimental Design: The activity of ganetespib was compared with that of the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd2e8a629f9d09a972e94fec0dc5f0c
https://doi.org/10.1158/1078-0432.c.6519806
https://doi.org/10.1158/1078-0432.c.6519806
Autor:
Geoffrey I. Shapiro, Kwok-Kin Wong, James Barsoum, Weiwen Ying, Matthew Meyerson, John-Paul Jimenez, Christa L. Borgman, Christopher D. Carey, Papiya Sinha, Yu-Chen Li, Julian Carretero, Danan Li, Liang Chen, Takayo Inoue, Scott J. Rodig, Jim Sang, Kevin P. Foley, Samanthi A. Perera, Takeshi Shimamura
PDF file, 1349K, Depletion of receptor tyrosine kinases and suppression of downstream signaling in HCC827 cells in response to 17-AAG or ganetespib-mediated HSP90 inhibition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5669f076684b25a070a2a8eace2f44c6
https://doi.org/10.1158/1078-0432.22443410
https://doi.org/10.1158/1078-0432.22443410
Autor:
Geoffrey I. Shapiro, Kwok-Kin Wong, James Barsoum, Weiwen Ying, Matthew Meyerson, John-Paul Jimenez, Christa L. Borgman, Christopher D. Carey, Papiya Sinha, Yu-Chen Li, Julian Carretero, Danan Li, Liang Chen, Takayo Inoue, Scott J. Rodig, Jim Sang, Kevin P. Foley, Samanthi A. Perera, Takeshi Shimamura
PDF file, 365K, Activity of ganetespib in HCC827 xenografts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f55e54fe0f3a4297ec6a21114ff77f
https://doi.org/10.1158/1078-0432.22443404.v1
https://doi.org/10.1158/1078-0432.22443404.v1
Autor:
Geoffrey I. Shapiro, Kwok-Kin Wong, James Barsoum, Weiwen Ying, Matthew Meyerson, John-Paul Jimenez, Christa L. Borgman, Christopher D. Carey, Papiya Sinha, Yu-Chen Li, Julian Carretero, Danan Li, Liang Chen, Takayo Inoue, Scott J. Rodig, Jim Sang, Kevin P. Foley, Samanthi A. Perera, Takeshi Shimamura
PDF file, 776K, Effects of 17-AAG and ganetespib on cell viability and mutant ERBB2 expression in ERBB2-dependent Ba/F3 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f63ea9ba3ce221874113a053ebe8665
https://doi.org/10.1158/1078-0432.22443392
https://doi.org/10.1158/1078-0432.22443392
Autor:
Geoffrey I. Shapiro, Kwok-Kin Wong, James Barsoum, Weiwen Ying, Matthew Meyerson, John-Paul Jimenez, Christa L. Borgman, Christopher D. Carey, Papiya Sinha, Yu-Chen Li, Julian Carretero, Danan Li, Liang Chen, Takayo Inoue, Scott J. Rodig, Jim Sang, Kevin P. Foley, Samanthi A. Perera, Takeshi Shimamura
PDF file, 136K, Median IC50's for NSCLC cell lines (with ganetespib and 17-AAG) with different genotypic subtypes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8fc5d7560e8ebf2280e3283ce0f0da
https://doi.org/10.1158/1078-0432.22443383
https://doi.org/10.1158/1078-0432.22443383
Autor:
Geoffrey I. Shapiro, Kwok-Kin Wong, James Barsoum, Weiwen Ying, Matthew Meyerson, John-Paul Jimenez, Christa L. Borgman, Christopher D. Carey, Papiya Sinha, Yu-Chen Li, Julian Carretero, Danan Li, Liang Chen, Takayo Inoue, Scott J. Rodig, Jim Sang, Kevin P. Foley, Samanthi A. Perera, Takeshi Shimamura
PDF file, 361K, Comparison of EGFR TKI and HSP90 inhibitor efficacy in Ba/F3 cells ectopically expressing different EGFR mutations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1786c91a1f98aabb40c79a7aec6b396d
https://doi.org/10.1158/1078-0432.22443380
https://doi.org/10.1158/1078-0432.22443380