Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Christa K. McIntyre"'
Autor:
Rimenez R. Souza, Mark B. Powers, Robert L. Rennaker, Christa K. McIntyre, Seth A. Hays, Michael P. Kilgard
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Studies have indicated that vagus nerve stimulation (VNS) enhances extinction learning in rodent models. Here, we investigated if pairing VNS with the conditioned stimulus is required for the enhancing effects of VNS. Adult Sprague–Dawley
Externí odkaz:
https://doaj.org/article/1e71fe4a81a644da98fbcfb9991124d2
Autor:
Lucas Canto-de-Souza, Peyton G. Demetrovich, Samantha Plas, Rimenez R. Souza, Joseph Epperson, Krista L. Wahlstrom, Ricardo Luiz Nunes-de-Souza, Ryan T. LaLumiere, Cleopatra Silva Planeta, Christa K. McIntyre
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
Post-traumatic stress disorder (PTSD) is associated with decreased activity in the prefrontal cortex. PTSD-like pathophysiology and behaviors have been observed in rodents exposed to a single prolonged stress (SPS) procedure. When animals are left al
Externí odkaz:
https://doaj.org/article/efb2e4bdf8fe405695565c178761cc6a
Publikováno v:
Journal of psychiatry and brain science. 7(4)
Anxiety disorders affect a large percentage of individuals who have an autism spectrum disorder (ASD). In children with ASD, excessive anxiety is also linked to gastrointestinal problems, self-injurious behaviors, and depressive symptoms. Exposure-ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a28cb13839e28b11b21a8165f1bc2010
https://pubmed.ncbi.nlm.nih.gov/36303861
https://pubmed.ncbi.nlm.nih.gov/36303861
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
The endurance of memories of emotionally arousing events serves the adaptive role of minimizing future exposure to danger and reinforcing rewarding behaviors. However, following a traumatic event, a subset of individuals suffers from persistent patho
Externí odkaz:
https://doaj.org/article/1933a9e8d91148a99f3c18a8c3dbfd99
Autor:
Jarid Goodman, Christa K. McIntyre
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
High levels of emotional arousal can impair spatial memory mediated by the hippocampus, and enhance stimulus-response (S-R) habit memory mediated by the dorsolateral striatum (DLS). The present study was conducted to determine whether these memory sy
Externí odkaz:
https://doaj.org/article/bb07a4d199d840f2b90168e083dccacf
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
Vagus nerve stimulation (VNS) enhances the consolidation of extinction of conditioned fear. High frequency stimulation of the infralimbic cortex (IL) produces long-term potentiation in the basolateral amygdala (BLA) in rats given VNS-paired extinctio
Externí odkaz:
https://doaj.org/article/647f4a6492ae476ea1e70e706e038179
Autor:
Christa K. McIntyre, Nicole M. Robertson, Ezek Mathew, Rimenez R. Souza, Michel N. Tabet, Robert L. Rennaker, Seth A. Hays, Michael P. Kilgard
Publikováno v:
Journal of Affective Disorders. 265:552-557
Background Chronic vagus nerve stimulation (VNS) attenuates anxiety in rats and humans. However, it is unclear whether VNS can promote acute anxiolytic effects. Here we examined short-term anxiolytic effects of VNS using single or multiple trains in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473719d12085b2540c61ea4714273f6c
https://doi.org/10.1016/j.jad.2019.11.090
https://doi.org/10.1016/j.jad.2019.11.090
Autor:
Kathleen K. Callahan, Rimenez R. Souza, Lindsey J. Noble, Ashleigh Chuah, Christa K. McIntyre
Publikováno v:
Learn Mem
Vagus nerve stimulation (VNS) enhances extinction of conditioned fear in rats. Previous findings support the hypothesis that VNS effects on extinction are due to enhanced consolidation of extinction memories through promotion of plasticity in extinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af46025eab2c002753babd385484b483
https://doi.org/10.1101/lm.048447.118
https://doi.org/10.1101/lm.048447.118
Autor:
Lindsey J. Noble, Venkat B. Meruva, Christa K. McIntyre, Robert L. Rennaker, Seth A. Hays, Michael P. Kilgard
Publikováno v:
Brain Stimulation, Vol 12, Iss 1, Pp 9-18 (2019)
Background Exposure-based therapies are used to treat a variety of trauma- and anxiety-related disorders by generating successful extinction following cue exposure during treatment. The development of adjuvant strategies that accelerate extinction le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b0976b90841feb7e3051c8256cc011d
http://www.sciencedirect.com/science/article/pii/S1935861X18303152
http://www.sciencedirect.com/science/article/pii/S1935861X18303152
Publikováno v:
Neurobiol Learn Mem
The basolateral complex of the amygdala (BLA) is critically involved in modulation of memory by stress hormones. Noradrenergic activation of the BLA enhances memory consolidation and plays a necessary role in the enhancing or impairing effects of str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52eace3b0214d145e87a43c35f15734d
https://pubmed.ncbi.nlm.nih.gov/34648950
https://pubmed.ncbi.nlm.nih.gov/34648950