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Autor:
Christa Ellen Nath, Andrew Grigg, Sebastian P. A. Rosser, Jane Estell, Elizabeth Newman, Campbell Tiley, Sundra Ramanathan, Shir Jing Ho, Stephen Larsen, John Gibson, Peter Presgrave, Peter John Shaw, Judith Trotman
Publikováno v:
European Journal of Clinical Pharmacology. 78:1911-1921
Aim To evaluate the accuracy of melphalan test dose pharmacokinetic (PK) predictions of the subsequent high dose (HDM) area under the concentration-versus-time curve (AUC) and to identify sources of prediction error (PE). Methods A prospective multic