Výsledky vyhledávání - "Christa Dias"

Abstract 5128: Characterization of tumor immune microenvironment in response to PD-L1 therapy initiated at different time points post inoculation in syngeneic mouse models

Autor: Christa Dias, Susan Wu, Geeta G. Sharma, Robert Mihalek, Matthew Gale, Wendy Grant, Nidia Hernandez, Ann Fiore

Publikováno v: Cancer Research. 76:5128-5128

The tumor microenvironment is an important aspect of cancer biology that contributes to tumor initiation, progression and responses to therapy. Cells and molecules of the immune system are fundamental components of the tumor microenvironment which ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5af98ba7952b43528687c81ef27f9848
https://doi.org/10.1158/1538-7445.am2016-5128

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Abstract B23: Chemoproteomic profiling of native kinases during the treatment of cells with kinase inhibitors

Autor: Geeta G. Sharma, Subha Vogeti, Christa Dias, Arwin Aban, Wendy Grant, Shuzhen Wu, Tyzoon K. Nomanbhoy, Jiangyue Wu, Alemayehu Senait, Heidi E. Brown

Publikováno v: Cancer Research. 76:B23-B23

Kinases are an important class of targets for a number of therapeutic indications, and currently, kinase inhibitors constitute a significant fraction of recently approved drugs, particularly for cancer. Using a probe-based chemoproteomics platform, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d68a3e7cc89a3c5cd1a41cf342d63196
https://doi.org/10.1158/1538-7445.fbcr15-b23

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Abstract 3092: In-situ Kinome wide profiling of Palbociclib treated COLO-205 human tumor xenograft samples

Autor: Christa Dias, Tyzoon K. Nomanbhoy, Shuzhen Wu, Geeta G. Sharma, Subha Vogeti, Arwin Aban, Wendy Grant, Jiangyue Wu

Publikováno v: Cancer Research. 75:3092-3092

Palbociclib (PD0332991) is a cyclin dependent kinase 4 and 6 inhibitor being developed for treatment of breast cancer. In order to evaluate the kinome-wide impacts of Palbociclib in an in-vivo setting, nude mice inoculated with COLO-205 (human colon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2d96a78f07dbc41fa7a249e0c4da0bc8
https://doi.org/10.1158/1538-7445.am2015-3092

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