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pro vyhledávání: '"Christa A, Blomquist"'
Autor:
Thomas C, Atack, Donald D, Raymond, Christa A, Blomquist, Charisse Flerida, Pasaje, Patrick R, McCarren, Jamie, Moroco, Henock B, Befekadu, Foxy P, Robinson, Debjani, Pal, Lisl Y, Esherick, Alessandra, Ianari, Jacquin C, Niles, William R, Sellers
Publikováno v:
ACS Medicinal Chemistry Letters
FK506-binding protein 35, FKBP35, has been implicated as an essential malarial enzyme. Rapamycin and FK506 exhibit antiplasmodium activity in cultured parasites. However, due to the highly conserved nature of the binding pockets of FKBPs and the immu