Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Chrissy M Leopold Wager"'
Autor:
Chrissy M Leopold Wager, Jordan R Bonifacio, Jan Simper, Adrian A Naoun, Eusondia Arnett, Larry S Schlesinger
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011297 (2023)
Macrophages are a first line of defense against pathogens. However, certain invading microbes modify macrophage responses to promote their own survival and growth. Mycobacterium tuberculosis (M.tb) is a human-adapted intracellular pathogen that explo
Externí odkaz:
https://doaj.org/article/86c951c3530c4adb9cc0e3e348070ab8
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007585 (2019)
Nuclear receptors (NRs) are ligand-activated transcription factors that are expressed in a variety of cells, including macrophages. For decades, NRs have been therapeutic targets because their activity can be pharmacologically modulated by specific l
Externí odkaz:
https://doaj.org/article/a9dac933679a464ab9c3ab55c977fba1
Autor:
Chrissy M Leopold Wager, Camaron R Hole, Althea Campuzano, Natalia Castro-Lopez, Hong Cai, Marley C Caballero Van Dyke, Karen L Wozniak, Yufeng Wang, Floyd L Wormley
Publikováno v:
PLoS Pathogens, Vol 14, Iss 10, p e1007358 (2018)
Development of vaccines against opportunistic infections is difficult as patients most at risk of developing disease are deficient in aspects of the adaptive immune system. Here, we utilized an experimental immunization strategy to induce innate memo
Externí odkaz:
https://doaj.org/article/9b8f5e1d82764f04b5dcd73c9a68a8b2
Autor:
Althea Campuzano, Natalia Castro-Lopez, Karen L Wozniak, Chrissy M Leopold Wager, Floyd L Wormley
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169347 (2017)
C-type lectin receptors (CLRs) are diverse, trans-membrane proteins that function as pattern recognition receptors (PRRs) which are necessary for orchestrating immune responses against pathogens. CLRs have been shown to play a major role in recogniti
Externí odkaz:
https://doaj.org/article/180d81c69f9d431ca7bacb379b35e34a
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening disease. These fungi commonly enter their host via inhalation into the lungs where they encounter resident phagocytes, including macrophages and dendritic cells, w
Externí odkaz:
https://doaj.org/article/a5cc983409cb4043a2aafecfac78dfdb
Publikováno v:
PLoS Pathogens, Vol 11, Iss 6, p e1004843 (2015)
Externí odkaz:
https://doaj.org/article/ab80b89e4dbc4cf38f5c02fd57b97233
Autor:
Ashok K Chaturvedi, Rumanasma S Hameed, Karen L Wozniak, Camaron R Hole, Chrissy M Leopold Wager, Susan T Weintraub, Jose L Lopez-Ribot, Floyd L Wormley
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104316 (2014)
Cryptococcus gattii is a fungal pathogen that can cause life-threatening respiratory and disseminated infections in immune-competent and immune-suppressed individuals. Currently, there are no standardized vaccines against cryptococcosis in humans, un
Externí odkaz:
https://doaj.org/article/006476fc0c804585ae736406f4ea1112
Autor:
Michal A. Olszewski, Floyd L. Wormley, Chrissy M. Leopold Wager, Althea Campuzano, Amanda J. Martinez, Chiung-Yu Hung, Natalia Castro-Lopez, Anutosh Ganguly
Publikováno v:
mBio, Vol 11, Iss 1, p e03005-19 (2020)
mBio
mBio, Vol 11, Iss 1 (2020)
mBio
mBio, Vol 11, Iss 1 (2020)
Cryptococcus neoformans is a fungal pathogen that is found throughout the environment and can cause life-threatening infections of the lung and central nervous system in severely immunocompromised individuals. Caspase recruitment domain-containing pr
Autor:
Floyd L. Wormley, Hong Cai, Chrissy M. Leopold Wager, Althea Campuzano, Yufeng Wang, Natalia Castro-Lopez, Karen L. Wozniak, Camaron R. Hole
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
Dendritic cells (DCs), a vital component of the innate immune system, are considered to lack antigen specificity and be devoid of immunological memory. Strategies that can induce memory-like responses from innate cells can be utilized to elicit prote
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 15, Iss 3, p e1007585 (2019)
PLoS Pathogens, Vol 15, Iss 3, p e1007585 (2019)
Nuclear receptors (NRs) are ligand-activated transcription factors that are expressed in a variety of cells, including macrophages. For decades, NRs have been therapeutic targets because their activity can be pharmacologically modulated by specific l