Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Chrispian W. Theron"'
Autor:
Chrispian W. Theron, J. Enrique Salcedo-Sora, Justine M. Grixti, Iben Møller-Hansen, Irina Borodina, Douglas B. Kell
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 938 (2024)
Clozapine is an antipsychotic drug whose accumulation in white cells can sometimes prove toxic; understanding the transporters and alleles responsible is thus highly desirable. We used a strategy in which a yeast (Saccharomyces cerevisiae) CRISPR-Cas
Externí odkaz:
https://doaj.org/article/032f87167c0842f9ba6f31b544fdf257
Publikováno v:
Microbial Biotechnology, Vol 12, Iss 6, Pp 1126-1138 (2019)
Summary Cytochrome P450 monooxygenases (P450) are enzymes with high potential as biocatalysts for industrial applications. Their large‐scale applications are, however, limited by instability and requirement for coproteins and/or expensive cofactors
Externí odkaz:
https://doaj.org/article/aab4e4a285984779b92963b831d9f720
Autor:
Julio Berrios, Chrispian W. Theron, Sébastien Steels, Belén Ponce, Edgar Velastegui, Cristina Bustos, Claudia Altamirano, Patrick Fickers
Publikováno v:
Microorganisms, Vol 10, Iss 7, p 1466 (2022)
Komagataella phaffii (aka Pichia pastoris) is a yeast able to grow in methanol as the sole carbon and energy source. This substrate is converted into formaldehyde, a toxic intermediary that can either be assimilated to biomass or dissimilated to CO2
Externí odkaz:
https://doaj.org/article/61dc359359c9416c829c7020c45c68bc
Publikováno v:
Microorganisms, Vol 7, Iss 8, p 229 (2019)
Non-conventional yeasts are efficient cell factories for the synthesis of value-added compounds such as recombinant proteins, intracellular metabolites, and/or metabolic by-products. Most bioprocess, however, are still designed to use pure, ideal sug
Externí odkaz:
https://doaj.org/article/153fe9e5b65b4de595a66eb4405ac691
Autor:
Lehlohonolo B. Qhanya, Ntsane T. Mthakathi, Charlotte E. Boucher, Samson S. Mashele, Chrispian W. Theron, Khajamohiddin Syed
Publikováno v:
South African Journal of Science, Vol 113, Iss 5/6, Pp 7-7 (2017)
Endocrine disrupting chemicals (EDCs) are synthetic chemicals that alter the function of endocrine systems in animals including humans. EDCs are considered priority pollutants and worldwide research is ongoing to develop bioremediation strategies to
Externí odkaz:
https://doaj.org/article/b4bc3b7eb7a145e5a2f9364a5ec34e78
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
The large-scale production of recombinant proteins (rProt) is becoming increasingly economically important. Among the different hosts used for rProt production, yeasts are gaining popularity. The so-called non-conventional yeasts, such as the methylo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bcccd2b921a9f48b05ff515c4f494ce7
http://link.springer.com/article/10.1038/s41598-020-58683-3
http://link.springer.com/article/10.1038/s41598-020-58683-3
Publikováno v:
Clinical Spectroscopy, Vol 3, Iss, Pp 100014-(2021)
Clinical Spectroscopy
Clinical Spectroscopy
In this study, we used stimulated Raman spectroscopy (SRS) microscopy to collect Raman signatures from live Saccharomyces cerevisiae cells in the spectral range 2804−3060 cm−1 and 830−2000 cm−1 with a spectral resolution of 8 cm−1. To effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb8c00f62f8b4583bb8f34a9f59ae0c
http://www.sciencedirect.com/science/article/pii/S2666054721000090
http://www.sciencedirect.com/science/article/pii/S2666054721000090
Autor:
Patrick Fickers, Christian Rodriguez, Samuel Telek, Sébastien Steels, Renaud Lecler, Julio Berrios, Chrispian W. Theron
Publikováno v:
Yeast. 36:285-296
Pichia pastoris is a very popular yeast for recombinant protein production, mainly due to the strong, methanol-inducible PAOX1 promoter. Methanol induction however poses several drawbacks. One approach to improve processes is to use MutS strains with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07c63abf7bea6c9117bd717c2f01a4e
https://doi.org/10.1002/yea.3388
https://doi.org/10.1002/yea.3388
Publikováno v:
Microbial Biotechnology
Microbial Biotechnology, Vol 12, Iss 6, Pp 1126-1138 (2019)
Microbial Biotechnology, Vol 12, Iss 6, Pp 1126-1138 (2019)
Summary Cytochrome P450 monooxygenases (P450) are enzymes with high potential as biocatalysts for industrial applications. Their large‐scale applications are, however, limited by instability and requirement for coproteins and/or expensive cofactors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969dd5920ec279e398b6aec268c0d490
https://doi.org/10.1111/1751-7915.13321
https://doi.org/10.1111/1751-7915.13321
Publikováno v:
HELIYON
Heliyon, Vol 5, Iss 7, Pp e02014-(2019)
Heliyon
Heliyon, Vol 5, Iss 7, Pp e02014-(2019)
Heliyon
Background Gram-negative bacteria actively secrete outer membrane vesicles into the surrounding environment and these vesicles have been shown to play various physiological and protective roles such as carrying antibiotic-degrading enzymes and acting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce3abd9b6a7d8bd223f7711b1eb73ce
https://pubmed.ncbi.nlm.nih.gov/31312732
https://pubmed.ncbi.nlm.nih.gov/31312732