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pro vyhledávání: '"Chrisna J. LeVaillant"'
Autor:
Wissam Chiha, Chrisna J LeVaillant, Carole A Bartlett, Alex W Hewitt, Phillip E Melton, Melinda Fitzgerald, Alan R Harvey
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192348 (2018)
Partial transection (PT) of the optic nerve is an established experimental model of secondary degeneration in the central nervous system. After a dorsal transection, retinal ganglion cells (RGCs) with axons in ventral optic nerve are intact but vulne
Externí odkaz:
https://doaj.org/article/d7ed955f0acd46cc9e5fcb5a1eebd7e0
Autor:
Chrisna J LeVaillant, Anil Sharma, Jill Muhling, Lachlan PG Wheeler, Greg S Cozens, Mats Hellström, Jennifer Rodger, Alan R Harvey
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Use of viral vectors to deliver therapeutic genes to the central nervous system holds promise for the treatment of neurodegenerative diseases and neurotrauma. Adeno-associated viral (AAV) vectors encoding brain-derived neurotrophic factor (BDNF) or c
Externí odkaz:
https://doaj.org/article/b89b177c22e24e439b4649bb0f248556
Autor:
Carole A. Bartlett, Melinda Fitzgerald, Chrisna J. LeVaillant, Phillip E. Melton, Alex W. Hewitt, Alan R. Harvey, Wissam Chiha
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192348 (2018)
PLoS ONE
PLoS ONE
Background Partial transection (PT) of the optic nerve is an established experimental model of secondary degeneration in the central nervous system. After a dorsal transection, retinal ganglion cells (RGCs) with axons in ventral optic nerve are intac
Publikováno v:
BMC Developmental Biology
Background Members of the Semaphorin 3 family (Sema3s) influence the development of the central nervous system, and some are implicated in regulating aspects of visual system development. However, we lack information about the timing of expression of
Autor:
Chrisna J. LeVaillant, Greg Cozens, Alan R. Harvey, Marisa Ryan, Jennifer Rodger, Lachlan P.G. Wheeler, Anne S. Kramer, Colette Moses, Margaret A. Pollett, Anil Sharma
Publikováno v:
eNeuro
Similar to neurons in the peripheral nervous system, immature CNS-derived RGCs become dependent on target-derived neurotrophic support as their axons reach termination sites in the brain. To study the factors that influence this developmental transit