Genetic regulation of OAS1 nonsense-mediated decay underlies association with risk of severe COVID-19.

Autor: Banday AR; Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Stanifer ML; Department of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, Heidelberg, Germany., Florez-Vargas O; Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Onabajo OO; Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Zahoor MA; Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.; Department of Immunology, University of Toronto, Toronto, ON, Canada., Papenberg BW; Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Ring TJ; Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Lee CH; Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Andreakos E; Laboratory of Immunobiology, Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece., Arons E; Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Barsh G; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA., Biesecker LG; Center for Precision Health Research, National Human Genome Research Institute, Bethesda, MD, USA., Boyle DL; Altman Clinical & Translational Research Institute, University of California San Diego Health Sciences, San Diego, CA, USA., Burnett-Hartman A; Institute for Health Research, Kaiser Permanente Colorado, Aurora, CO, USA., Carrington M; Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA.; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Chang E; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Choe PG; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Chrisholm RL; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Dalgard C; Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Edberg J; Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA., Erdmann N; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA., Feigelson HS; Institute for Health Research, Kaiser Permanente Colorado, Aurora, CO, USA., Firestein GS; Altman Clinical & Translational Research Institute, University of California San Diego Health Sciences, San Diego, CA, USA., Gehring AJ; Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.; Department of Immunology, University of Toronto, Toronto, ON, Canada., Ho M; Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Holland S; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Hutchinson AA; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Im H; Genome Opinion Inc, Seoul, Republic of Korea., Ison MG; Divisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Kim HB; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea., Kreitman RJ; Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Korf BR; Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA., Mirabello L; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Pacheco JA; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Peluso MJ; Division of HIV, Infectious Diseases and Global Medicine, University of California, San Francisco, CA, USA., Rader DJ; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Redden DT; Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA., Ritchie MD; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Rosenbloom B; Center for Precision Health Research, National Human Genome Research Institute, Bethesda, MD, USA., Sant Anna HP; Laboratory of Genetic Susceptibility, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Savage S; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Siouti E; Laboratory of Immunobiology, Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece., Triantafyllia V; Laboratory of Immunobiology, Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens., Vargas JM; Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Verma A; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Vij V; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Wesemann DR; Department of Medicine, Division of Allergy and Immunology, Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Yeager M; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Yu X; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Zhang Y; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Boulant S; Division of Cellular Polarity and Viral Infection, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Infectious Diseases, Virology, University Hospital Heidelberg, Heidelberg, Germany., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Feld JJ; Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.; Department of Immunology, University of Toronto, Toronto, ON, Canada., Prokunina-Olsson L; Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2021 Jul 13. Date of Electronic Publication: 2021 Jul 13.