Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Chris van der Poel"'
Autor:
Abdulsatar Jamal, Holly Brettle, Dina A. Jamil, Vivian Tran, Henry Diep, Alexander Bobik, Chris van der Poel, Antony Vinh, Grant R. Drummond, Colleen J. Thomas, Maria Jelinic, Hayder A. Al-Aubaidy
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 637 (2024)
Metabolic syndrome (MetS) is a cluster of metabolic abnormalities affecting ~25% of adults and is linked to chronic diseases such as cardiovascular disease, cancer, and neurodegenerative diseases. Oxidative stress and inflammation are key drivers of
Externí odkaz:
https://doaj.org/article/5a37d69efed34c2c8f7e20e552259daf
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 434 (2023)
The recessive Ryanodine Receptor Type 1 (RyR1) P3527S mutation causes mild muscle weakness in patients and increased resting cytoplasmic [Ca2+] in transformed lymphoblastoid cells. In the present study, we explored the cellular/molecular effects of t
Externí odkaz:
https://doaj.org/article/a7ffc244072f4994b18bff5e5072613e
Publikováno v:
Journal of Developmental Biology, Vol 10, Iss 4, p 49 (2022)
Organophosphate (OP) insecticides are used to eliminate agricultural threats posed by insects, through inhibition of the neurotransmitter acetylcholinesterase (AChE). These potent neurotoxins are extremely efficacious in insect elimination, and as su
Externí odkaz:
https://doaj.org/article/2ee27f5b8dd442c5956592defb730d3a
Autor:
Mujun Sun, Rhys D. Brady, Chris van der Poel, Danielle Apted, Bridgette D. Semple, Jarrod E. Church, Terence J. O'Brien, Stuart J. McDonald, Sandy R. Shultz
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Traumatic brain injury (TBI) often involves multitrauma in which concurrent extracranial injury occurs. We previously demonstrated that a long bone fracture exacerbates neuroinflammation and functional outcomes in mice given a TBI. Whether other form
Externí odkaz:
https://doaj.org/article/e422ccaac818413bb8ab75aa128bf0cb
Publikováno v:
Sports, Vol 6, Iss 4, p 109 (2018)
An increasing number of studies have shown supplementation with the amino acid taurine to have promise in ameliorating dystrophic symptoms in the mdx mouse model of Duchenne Muscular Dystrophy (DMD). Here we build on this limited body of work by inve
Externí odkaz:
https://doaj.org/article/f538e18ae10645668fe04d2ada416ad0
Autor:
Natasha McRae, Leonard Forgan, Bryony McNeill, Alex Addinsall, Daniel McCulloch, Chris Van der Poel, Nicole Stupka
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 12, p 2629 (2017)
In Duchenne muscular dystrophy (DMD), a dysregulated extracellular matrix (ECM) directly exacerbates pathology. Glucocorticoids are beneficial therapeutics in DMD, and have pleiotropic effects on the composition and processing of ECM proteins in othe
Externí odkaz:
https://doaj.org/article/f8e8c98ebd2a426eb18907c83ee12d57
Autor:
Aleksandar Dobric, Ross Vlahos, Kurt Brassington, Claudia Cerni, Stanley M H Chan, S Passey, Chris van der Poel, Huei Jiunn Seow, Ivan Bernardo, Stavros Selemidis, Steven Bozinovski
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Skeletal muscle dysfunction in patients with chronic obstructive pulmonary disease negatively impacts quality of life and survival. Cigarette smoking (CS) is the major risk factor for chronic obstructive pulmonary disease and skeletal muscle dysfunct
Autor:
Chris van der Poel, Caroline J. Taylor, J. H. Fitton, Brett K. Thompson, Ah Y. Park, Sam Karpiniec, Jarrod E Church, Damien N. Stringer, Sally E. McBean
Publikováno v:
Physiological Reports, Vol 9, Iss 3, Pp n/a-n/a (2021)
Physiological Reports
Physiological Reports
Fucoidan is a sulfated polysaccharide found in a range of brown algae species. Growing evidence supports the long‐term supplementation of fucoidan as an ergogenic aid to improve skeletal muscle performance. The aim of this study was to investigate
Autor:
Robyn M. Murphy, Barnaby P. Frankish, Bradley S. Launikonis, Harriet P. Lo, Paul D. Allen, Aldo Meizoso-Huesca, Luke Pearce, Cedric R. Lamboley, Chris van der Poel, Charles Ferguson, Robert G. Parton, Crystal Seng, Christopher John Barclay, Vikas Kaura, Daniel P. Singh, Philip M. Hopkins
Publikováno v:
Science Advances
Description
RyR1 Ca2+ leak causes a cascade of events that shifts Ca2+ to the cytoplasm and mitochondria, supporting force generation.
Muscle contraction depends on tightly regulated Ca2+ release. Aberrant Ca2+ leak through ryanodine recept
RyR1 Ca2+ leak causes a cascade of events that shifts Ca2+ to the cytoplasm and mitochondria, supporting force generation.
Muscle contraction depends on tightly regulated Ca2+ release. Aberrant Ca2+ leak through ryanodine recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f23394ad8035d2256dda06c6eae76be
Autor:
Taryan L Kotsiakos, Taylah R Cook, Zoe M. Smith, Craig R. Wright, Alex B. Addinsall, Chris van der Poel, Nicole Stupka, Sofianos Andrikopoulos
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 318(5)
Selenoprotein S (Seps1) can be protective against oxidative, endoplasmic reticulum (ER), and inflammatory stress. Seps1 global knockout mice are less active, possess compromised fast muscle ex vivo strength, and, depending on context, heightened infl