Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Chris Vigna"'
Autor:
Val A. Fajardo, Eric Bombardier, Elliott McMillan, Khanh Tran, Brennan J. Wadsworth, Daniel Gamu, Andrew Hopf, Chris Vigna, Ian C. Smith, Catherine Bellissimo, Robin N. Michel, Mark A. Tarnopolsky, Joe Quadrilatero, A. Russell Tupling
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 8, Pp 999-1009 (2015)
Centronuclear myopathy (CNM) is a congenital myopathy that is histopathologically characterized by centrally located nuclei, central aggregation of oxidative activity, and type I fiber predominance and hypotrophy. Here, we obtained commercially avail
Externí odkaz:
https://doaj.org/article/5c1b60ecd4ac4318a37bb7998cf58ece
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68924 (2013)
The main purpose of this study was to directly quantify the relative contribution of Ca²⁺ cycling to resting metabolic rate in mouse fast (extensor digitorum longus, EDL) and slow (soleus) twitch skeletal muscle. Resting oxygen consumption of isol
Externí odkaz:
https://doaj.org/article/cb7e86b6c12b44b1b1fb96ff15dfc23e
Autor:
Val A Fajardo, Eric Bombardier, Chris Vigna, Tahira Devji, Darin Bloemberg, Daniel Gamu, Anthony O Gramolini, Joe Quadrilatero, A Russell Tupling
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84304 (2013)
Sarcolipin (SLN) and phospholamban (PLN) inhibit the activity of sarco(endo)plasmic reticulum Ca(2+)-ATPases (SERCAs) by reducing their apparent affinity for Ca(2+). A ternary complex between SLN, PLN, and SERCAs results in super-inhibition of SERCA
Externí odkaz:
https://doaj.org/article/0efab317743743239fda5a28558b9a38
Publikováno v:
Applied ergonomics. 101
To determine the state of the literature on assessing heat-stress using physiological parameters. To provide recommendations to the nuclear industry regarding worker heat-stress management practices.A scoping review identified relevant articles. A se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1d3f4c58c6ffdfdaf3e564f0337cfe
https://pubmed.ncbi.nlm.nih.gov/35139444
https://pubmed.ncbi.nlm.nih.gov/35139444
Autor:
Andrew Hopf, Catherine Bellissimo, A. Russell Tupling, Ian C. Smith, Elliott M. McMillan, Mark A. Tarnopolsky, Khanh Tran, Val A. Fajardo, Brennan J. Wadsworth, Eric Bombardier, Robin N. Michel, Daniel Gamu, Joe Quadrilatero, Chris Vigna
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 8, Pp 999-1009 (2015)
Disease Models & Mechanisms
Disease Models & Mechanisms
Centronuclear myopathy (CNM) is a congenital myopathy that is histopathologically characterized by centrally located nuclei, central aggregation of oxidative activity, and type I fiber predominance and hypotrophy. Here, we obtained commercially avail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2fea16f6f874f58cc16ccf8f22e39d5
http://dmm.biologists.org/content/8/8/999
http://dmm.biologists.org/content/8/8/999
Autor:
Graham P. Holloway, Patrick Schrauwen, A.R. Tupling, Eric A.F. Herbst, Sabina Paglialunga, Alison C. Ludzki, Joris Hoeks, J. S. V. Lally, Swati S. Jain, Arend Bonen, Chris Vigna
Publikováno v:
Diabetes, 63(6), 1907-1913. American Diabetes Association
Calcium/calmodulin dependent protein kinase (CaMK) activation induces mitochondrial biogenesis in response to increasing cytosolic calcium concentrations. Calcium leak from the ryanodine receptor is regulated by reactive oxygen species (ROS), which a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e513b3a47066ef46a936026fd39d94cf
https://cris.maastrichtuniversity.nl/en/publications/07f064a0-39c2-4927-b4b8-747d997b2363
https://cris.maastrichtuniversity.nl/en/publications/07f064a0-39c2-4927-b4b8-747d997b2363
Autor:
Eric Bombardier, Naresh C. Bal, Ian C. Smith, A. Russell Tupling, Daniel Gamu, Val A. Fajardo, Ryan A. Sayer, Muthu Periasamy, Subash C. Gupta, Chris Vigna
Publikováno v:
The FASEB Journal. 27:3871-3878
Sarcolipin (SLN) regulates muscle-based nonshivering thermogenesis and is up-regulated with high-fat feeding (HFF). To investigate whether other muscle-based thermogenic systems compensate for a lack of Sln and to firmly establish SLN as a mediator o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13ddd89e7784aa088fe1843ac46422c
https://doi.org/10.1096/fj.13-230631
https://doi.org/10.1096/fj.13-230631
Autor:
M. Anthony Verity, Perry B. Shieh, A. Russell Tupling, Tamara B. Horwich, Chris Vigna, Holly R. Middlekauff, Michele A. Hamilton, Gregg C. Fonarow
Publikováno v:
Journal of Cardiac Failure. 18:724-733
Background In the failing human heart, abnormalities of Ca 2+ cycling have been described, but there is scant knowledge about Ca 2+ handling in the skeletal muscle of humans with heart failure (HF). We tested the hypothesis that in humans with HF, Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8e2d81a29e93d210bbe8642fcb1c94
https://doi.org/10.1016/j.cardfail.2012.07.005
https://doi.org/10.1016/j.cardfail.2012.07.005
Publikováno v:
Journal of Applied Physiology. 113:246-254
The purpose of this investigation was to determine the effects of acute physiological GSH administration on endothelium-mediated reduction in coronary vascular resistance (CVR) using isolated perfused Sprague-Dawley rat hearts. A dose-response curve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f111e71c8d20bc9ff0e93f952a49144
https://doi.org/10.1152/japplphysiol.00589.2011
https://doi.org/10.1152/japplphysiol.00589.2011
Publikováno v:
Experimental Gerontology. 46:803-810
The senescent heart has decreased systolic and diastolic functions, both of which could be related to alterations in cardiac sarcoplasmic reticulum (SR) calcium (Ca(2+)) handling. The purpose of this study was to determine if SR protein content and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5427a7db7e7a1d87a3d285ac7b35b067
https://doi.org/10.1016/j.exger.2011.06.005
https://doi.org/10.1016/j.exger.2011.06.005