Zobrazeno 1 - 10
of 397
pro vyhledávání: '"Chris Vervaet"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 854 (2024)
Binder selection is a crucial step in continuous twin-screw wet granulation (TSWG), as the material experiences a much shorter residence time (2–40 s) in the granulator barrel compared to batch-wise granulation processes. Polyvinyl alcohol (PVA) 4-
Externí odkaz:
https://doaj.org/article/c0a5bb1bd8d844ee998b0f13ff919faa
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 341 (2024)
Hydroxypropyl methylcellulose (HPMC) is a preferred hydrophilic matrix former for controlled release formulations produced through continuous twin-screw wet granulation. However, a non-homogeneous API distribution over sieve fractions with underdosin
Externí odkaz:
https://doaj.org/article/c172cef54dd244498f61f132bf954ae3
Autor:
Aseel Samaro, Maarten Vergaelen, Martin Purino, Ali Tigrine, Victor R. de la Rosa, Niloofar Moazami Goudarzi, Matthieu N. Boone, Valérie Vanhoorne, Richard Hoogenboom, Chris Vervaet
Publikováno v:
Materials Today Bio, Vol 16, Iss , Pp 100414- (2022)
Sustaining the release of highly dosed APIs from a matrix tablet is challenging. To address this challenge, this study evaluated the performance of thermoplastic poly (2-alkyl-2-oxazoline)s (PAOx) as matrix excipient to produce sustained-release tabl
Externí odkaz:
https://doaj.org/article/3f95825cf65946ae88e09622ff78bc85
Autor:
Zaira Manigrasso, Wannes Goethals, Niloofar M. Goudarzi, Matthieu N. Boone, Aseel Samaro, Chris Vervaet, Wilfried Philips, Jan Aelterman
Publikováno v:
Frontiers in Materials, Vol 9 (2022)
Digital volume correlation (DVC) is a 3D image-based technique for displacement and strain computation. Traditionally, both (digital image correlation) DIC and DVC are methods based on two individual time frames; the estimation of the displacement an
Externí odkaz:
https://doaj.org/article/593f591d24044d78ab1718c65682f8df
Autor:
Tryfon Digkas, Alina Porfire, Jeroen Van Renterghem, Aseel Samaro, Gheorghe Borodi, Chris Vervaet, Andrea Gabriela Crișan, Sonia Iurian, Thomas De Beer, Ioan Tomuta
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1062 (2023)
The present study aimed to develop 3D printed dosage forms, using custom-made filaments loaded with diclofenac sodium (DS). The printed tablets were developed by implementing a quality by design (QbD) approach. Filaments with adequate FDM 3D printing
Externí odkaz:
https://doaj.org/article/79bf6d34b8734f32b2c23a73597116f7
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 538 (2023)
Diazepam (DZP) is a long-acting benzodiazepine to treat anxiety or acute alcohol withdrawal. Although this class of drugs should be taken for a short period of time, many patients take them for longer than recommended, which has been linked to an inc
Externí odkaz:
https://doaj.org/article/3aa614190fdc46e28660ab05cb65dfbe
Autor:
Christoph Portier, Tamas Vigh, Giustino Di Pretoro, Jan Leys, Didier Klingeleers, Thomas De Beer, Chris Vervaet, Valérie Vanhoorne
Publikováno v:
International Journal of Pharmaceutics: X, Vol 3, Iss , Pp 100077- (2021)
Despite significant advances in the research domain of continuous twin screw granulation, limited information is currently available on the impact of raw material properties, especially considering batch-to-batch variability. The importance of raw ma
Externí odkaz:
https://doaj.org/article/7b5b47b81cd84b6d90d660515d4b07d0
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2475 (2022)
Visualization of the dynamic behavior of pharmaceutical dosage forms during the dissolution process offers a better understanding of the drug release mechanism, enabling the design of customized dosage forms. In this study, an X-ray tomography-based
Externí odkaz:
https://doaj.org/article/b37ec8374d5f4c6da2c27f56002961d3
Autor:
Clara Guarch-Pérez, Bahaa Shaqour, Martijn Riool, Bart Verleije, Koen Beyers, Chris Vervaet, Paul Cos, Sebastian A. J. Zaat
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1363 (2022)
Bacterial infections are a serious healthcare complication in orthopedic and trauma surgery worldwide. Compared to systemic, local antibiotic prophylaxis has been shown to provide a higher antibiotic dose and bioavailability at the bone site with min
Externí odkaz:
https://doaj.org/article/0f8403bf84c64581addac0cc0ad3ad34
Autor:
Gust Nuytten, Susan Ríos Revatta, Pieter-Jan Van Bockstal, Ashish Kumar, Joris Lammens, Laurens Leys, Brecht Vanbillemont, Jos Corver, Chris Vervaet, Thomas De Beer
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2076 (2021)
During the spin freezing step of a recently developed continuous spin freeze-drying technology, glass vials are rapidly spun along their longitudinal axis. The aqueous drug formulation subsequently spreads over the inner vial wall, while a cold gas f
Externí odkaz:
https://doaj.org/article/8426039a85ab42959ba7b16b7114420a