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pro vyhledávání: '"Chris Vandervert"'
Autor:
Jennifer S. Smith, Michael A. Pleiss, Caroline Garrido, Ying-Zi Xu, Frank Stappenbeck, Elizabeth Messersmith, Frederique Bard, Bhushan Samant, Linda Mutter, Semko Christopher M, Brent Welch, Brian P. Stupi, Chris Vandervert, Mark Dreyer, Zhenmei Liao, Mike Krimm, Brian Wipke, Ian Gallager, Ted Yednock, Michael S. Dappen, Andrei W. Konradi, Lilibeth Dofiles
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:3070-3074
A series of (S)-2-(2-(diethylamino)-5-(N-alkyl-N-sulfonamido)pyrimidin-4-ylamino)-3-(4-(carbamoyloxy)phenyl)propanoic acid is discovered as orally available VLA-4 antagonists. Representative compounds 11b and 11p showed efficacy in multiple in vivo a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f333c01a36b2c1dca73c9d1c52f995
https://doi.org/10.1016/j.bmcl.2013.03.010
https://doi.org/10.1016/j.bmcl.2013.03.010
